Upregulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain

Autor: Agostini, Francesco, Pereyra, Leonardo, Dale, Justin, Yambire, King Faisal, Maglioni, Silvia, Schiavi, Alfonso, Ventura, Natascia, Milosevic, Ira, Raimundo, Nuno

Publikováno v: In Journal of Biological Chemistry July 2024 300(7)

Predictive Models for Long Term Survival of AML Patients Treated with Venetoclax and Azacitidine or 7+3 Based on Post Treatment Events and Responses: Retrospective Cohort Study.

Autor: Islam N; RefinedScience, Aurora, CO, United States., Reuben JS; RefinedScience, Aurora, CO, United States., Dale J; RefinedScience, Aurora, CO, United States., Coates JW; RefinedScience, Aurora, CO, United States., Sapiah K; RefinedScience, Aurora, CO, United States., Markson FR; RefinedScience, Aurora, CO, United States., Jordan CT; Division of Hematology, University of Colorado Anschutz, Aurora, CO, United States., Smith C; Department of Medicine, University of Colorado Anschutz, Aurora, CO, United States.

Publikováno v: JMIR cancer [JMIR Cancer] 2024 Aug 21; Vol. 10, pp. e54740. Date of Electronic Publication: 2024 Aug 21.

Machine Learning-Based Exploratory Clinical Decision Support for Newly Diagnosed Patients With Acute Myeloid Leukemia Treated With 7 + 3 Type Chemotherapy or Venetoclax/Azacitidine.

Autor: Islam N; Optum Labs, Minnetonka, MN., Reuben JS; UCHealth, Aurora, CO., Dale J; Department of Medicine, University of Colorado, Aurora, CO., Gutman J; Department of Medicine, University of Colorado, Aurora, CO., McMahon CM; Department of Medicine, University of Colorado, Aurora, CO., Amaya M; Department of Medicine, University of Colorado, Aurora, CO., Goodman B; Optum Labs, Minnetonka, MN., Toninato J; Optum Labs, Minnetonka, MN., Gasparetto M; Department of Medicine, University of Colorado, Aurora, CO., Stevens B; Department of Medicine, University of Colorado, Aurora, CO., Pei S; Department of Medicine, University of Colorado, Aurora, CO., Gillen A; Department of Medicine, University of Colorado, Aurora, CO., Staggs S; Department of Medicine, University of Colorado, Aurora, CO., Engel K; Department of Medicine, University of Colorado, Aurora, CO., Davis S; Department of Medicine, University of Colorado, Aurora, CO., Hull M; Health Data Compass, Colorado Center for Personalized Medicine, University of Colorado, Aurora, CO., Burke E; UCHealth, Aurora, CO., Larchick L; UCHealth, Aurora, CO., Zane R; UCHealth Care Innovations and Department of Emergency Medicine, University of Colorado, Aurora, CO., Weller G; Optum Labs, Minnetonka, MN., Jordan C; Department of Medicine, University of Colorado, Aurora, CO., Smith C; Department of Medicine, University of Colorado, Aurora, CO.

Publikováno v: JCO clinical cancer informatics [JCO Clin Cancer Inform] 2022 Sep; Vol. 6, pp. e2200030.

Application of HL7/LOINC Document Ontology to a University-Affiliated Integrated Health System Research Clinical Data Repository.

Autor: Wang Y; Institute for Health Informatics., Pakhomov S; Institute for Health Informatics ; College of Pharmacy., Dale JL; Academic Health Center - Information Systems., Chen ES; Center for Clinical & Translational Science ; Department of Medicine ; Department of Computer Science, University of Vermont, Burlington, VT., Melton GB; Institute for Health Informatics ; Department of Surgery, University of Minnesota, Minneapolis, MN.

Publikováno v: AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science [AMIA Jt Summits Transl Sci Proc] 2014 Apr 07; Vol. 2014, pp. 230-4. Date of Electronic Publication: 2014 Apr 07 (Print Publication: 2014).