Zobrazeno 1 - 10
of 1 686
pro vyhledávání: '"Dale, I"'
Autor:
Catarina F. Almeida, Benjamin S. Gully, Claerwen M. Jones, Lukasz Kedzierski, Sachith D. Gunasinghe, Michael T. Rice, Richard Berry, Nicholas A. Gherardin, Trang T. Nguyen, Yee-Foong Mok, Josephine F. Reijneveld, D. Branch Moody, Ildiko Van Rhijn, Nicole L. La Gruta, Adam P. Uldrich, Jamie Rossjohn, Dale I. Godfrey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract αβ T cell receptors (αβTCRs) co-recognise antigens when bound to Major Histocompatibility Complex (MHC) or MHC class I-like molecules. Additionally, some αβTCRs can bind non-MHC molecules, but how much intact antigen reactivities are a
Externí odkaz:
https://doaj.org/article/a4fb52352ddb44ba9d2176f3352758f0
Autor:
Li, Mogeng, de Silva, Charitha M., Chung, Daniel, Pullin, Dale I., Marusic, Ivan, Hutchins, Nicholas
Publikováno v:
Journal of Fluid Mechanics, 923, A18 (2021)
This study presents an experimental dataset documenting the evolution of a turbulent boundary layer downstream of a rough-to-smooth surface transition. To investigate the effect of upstream flow conditions, two groups of experiments are conducted. Fo
Externí odkaz:
http://arxiv.org/abs/2308.02890
Autor:
Julio Carrera Montoya, Simon Collett, Daniel Fernandez Ruiz, Linda Earnest, Melissa A. Edeling, Ashley Huey Yiing Yap, Chinn Yi Wong, James P. Cooney, Kathryn C. Davidson, Jason Roberts, Steven Rockman, Bang M. Tran, Julie L. McAuley, Georgia Deliyannis, Samantha L. Grimley, Damian F. J. Purcell, Shafagh A. Waters, Dale I. Godfrey, Dhiraj Hans, Marc Pellegrini, Jason M. Mackenzie, Elizabeth Vincan, William R. Heath, Joseph Torresi
Publikováno v:
Organoids, Vol 3, Iss 1, Pp 18-31 (2024)
Existing mRNA COVID-19 vaccines have shown efficacy in reducing severe cases and fatalities. However, their effectiveness against infection caused by emerging SARS-CoV-2 variants has waned considerably, necessitating the development of variant vaccin
Externí odkaz:
https://doaj.org/article/cf1701857c3e4eef8731f1d72ff37ded
Autor:
Anna H. Mooney, Sarah L. Draper, Olivia K. Burn, Regan J. Anderson, Benjamin J. Compton, Chingwen Tang, Kathryn J. Farrand, Pietro Di Lucia, Micol Ravà, Valeria Fumagalli, Leonardo Giustini, Elisa Bono, Dale I. Godfrey, William R. Heath, Weiming Yuan, Francis V. Chisari, Luca G. Guidotti, Matteo Iannacone, John Sidney, Alessandro Sette, Shivali A. Gulab, Gavin F. Painter, Ian F. Hermans
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101038- (2024)
Background & Aims: Liver diseases resulting from chronic HBV infection are a significant cause of morbidity and mortality. Vaccines that elicit T-cell responses capable of controlling the virus represent a treatment strategy with potential for long-t
Externí odkaz:
https://doaj.org/article/ee2629abc47b4a819f89b5234ea4bfff
Autor:
Mooney, Anna H., Draper, Sarah L., Burn, Olivia K., Anderson, Regan J., Compton, Benjamin J., Tang, Chingwen, Farrand, Kathryn J., Di Lucia, Pietro, Ravà, Micol, Fumagalli, Valeria, Giustini, Leonardo, Bono, Elisa, Godfrey, Dale I., Heath, William R., Yuan, Weiming, Chisari, Francis V., Guidotti, Luca G., Iannacone, Matteo, Sidney, John, Sette, Alessandro, Gulab, Shivali A., Painter, Gavin F., Hermans, Ian F.
Publikováno v:
In JHEP Reports May 2024 6(5)
Autor:
Tanja D de Gruijl, Roeland Lameris, Jamie Rossjohn, Myrthe Veth, David Lutje Hulsik, Adam Shahine, Bart Westerman, Dale I Godfrey, Patricia Brouwer, Hans J van der Vliet
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background CD1d is a monomorphic major histocompatibility complex class I-like molecule that presents lipid antigens to distinct T-cell subsets and can be expressed by various malignancies. Antibody-mediated targeting of CD1d on multiple myeloma cell
Externí odkaz:
https://doaj.org/article/44eecee2a3e44705a7cd0649a4af661d
Autor:
Terry M. Nolan, Georgia Deliyannis, Maryanne Griffith, Sabine Braat, Lilith F. Allen, Jennifer Audsley, Amy W. Chung, Marcin Ciula, Nicholas A. Gherardin, Michelle L. Giles, Tom P. Gordon, Samantha L. Grimley, Lana Horng, David C. Jackson, Jennifer A. Juno, Katherine Kedzierska, Stephen J. Kent, Sharon R. Lewin, Mason Littlejohn, Hayley A. McQuilten, Francesca L. Mordant, Thi H.O. Nguyen, Vanessa Pac Soo, Briony Price, Damian F.J. Purcell, Pradhipa Ramanathan, Samuel J. Redmond, Steven Rockman, Zheng Ruan, Joseph Sasadeusz, Julie A. Simpson, Kanta Subbarao, Stewart A. Fabb, Thomas J. Payne, Asuka Takanashi, Chee Wah Tan, Joseph Torresi, Jing Jing Wang, Lin-Fa Wang, Hareth Al-Wassiti, Chinn Yi Wong, Sophie Zaloumis, Colin W. Pouton, Dale I. Godfrey
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104878- (2023)
Summary: Background: SARS-CoV-2 booster vaccination should ideally enhance protection against variants and minimise immune imprinting. This Phase I trial evaluated two vaccines targeting SARS-CoV-2 beta-variant receptor-binding domain (RBD): a recomb
Externí odkaz:
https://doaj.org/article/759603e2b16e4eff9551a0f453f831d4
Autor:
Nolan, Terry M., Deliyannis, Georgia, Griffith, Maryanne, Braat, Sabine, Allen, Lilith F., Audsley, Jennifer, Chung, Amy W., Ciula, Marcin, Gherardin, Nicholas A., Giles, Michelle L., Gordon, Tom P., Grimley, Samantha L., Horng, Lana, Jackson, David C., Juno, Jennifer A., Kedzierska, Katherine, Kent, Stephen J., Lewin, Sharon R., Littlejohn, Mason, McQuilten, Hayley A., Mordant, Francesca L., Nguyen, Thi H.O., Soo, Vanessa Pac, Price, Briony, Purcell, Damian F.J., Ramanathan, Pradhipa, Redmond, Samuel J., Rockman, Steven, Ruan, Zheng, Sasadeusz, Joseph, Simpson, Julie A., Subbarao, Kanta, Fabb, Stewart A., Payne, Thomas J., Takanashi, Asuka, Tan, Chee Wah, Torresi, Joseph, Wang, Jing Jing, Wang, Lin-Fa, Al-Wassiti, Hareth, Wong, Chinn Yi, Zaloumis, Sophie, Pouton, Colin W., Godfrey, Dale I.
Publikováno v:
In eBioMedicine December 2023 98
Autor:
Florian Wiede, Benjamin J. Shields, Sock Hui Chew Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L. Tremblay, Sarah M. Russell, Dale I. Godfrey, Tony Tiganis
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Externí odkaz:
https://doaj.org/article/4909791187f149db9c3967eac3a5b7b2
We present wall-resolved large-eddy simulations (LES) of the incompressible Navier-Stokes equations together with empirical modeling for {turbulent} Taylor-Couette {(TC)} flow where the inner cylinder is rotating with angular velocity $\Omega_i$ and
Externí odkaz:
http://arxiv.org/abs/1908.06577