Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Dale, Dorsett"'
Autor:
Ray Kreienkamp, Simona Graziano, Nuria Coll-Bonfill, Gonzalo Bedia-Diaz, Emily Cybulla, Alessandro Vindigni, Dale Dorsett, Nard Kubben, Luis Francisco Zirnberger Batista, Susana Gonzalo
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2006-2015 (2018)
Summary: Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disease caused by a truncated lamin A protein (progerin) that drives cellular and organismal decline. HGPS patient-derived fibroblasts accumulate genomic instability, but its u
Externí odkaz:
https://doaj.org/article/8fbed131594d490c940628cc3115aad2
Autor:
Chris Oliver, Laura Groves, Blake D. Hansen, Masoud Salehi, Shaydah Kheradmand, Cheri S. Carrico, Patti Caudill, Mark Mattingly, Dale Dorsett, Stephenson Chea, Vijay Pratap Singh, Ian D. Krantz, Sylvia Huisman, Matthew A. Deardorff, Antonie D. Kline
Publikováno v:
American Journal of Medical Genetics Part A. 188:1005-1014
Cornelia de Lange syndrome (CdLS) is a spectrum disorder due to variants in genes of the cohesin protein complex. The following abstracts are from the Cornelia de Lange Syndrome Scientific and Educational Symposium held virtually in October 2020. Asp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fba88a08a5cca0354f8fa3e280291fb
https://doi.org/10.1002/ajmg.a.62591
https://doi.org/10.1002/ajmg.a.62591
Autor:
Jelena Stajic, Di Jiang, Caroline Ash, Matthias Georg von Herrath, Beverly A. Purnell, Dan A. Erkes, H. Jesse Smith, Stella M. Hurtley, Pamela J. Hines, Marc S. Lavine, Ian S. Osborne, Sacha Vignieri, Michael A. Funk, Annalisa M. VanHook, Caitlin Czajka, Dale Dorsett
Publikováno v:
Science. 376:1281-1283
Highlights from the Science family of journals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce65e94d27b1934b2e35509c12fa65a7
https://doi.org/10.1126/science.add4298
https://doi.org/10.1126/science.add4298
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007225 (2018)
The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division. Cohesin also participates in DNA repair and gene transcription. The Nipped-B-Mau2 protein com
Externí odkaz:
https://doaj.org/article/6769836d2c324b8bac3210c497ca0e7f
Autor:
Amanda Swain, Ziva Misulovin, Michelle Pherson, Maria Gause, Kathie Mihindukulasuriya, Ryan A Rickels, Ali Shilatifard, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006331 (2016)
The cohesin protein complex mediates sister chromatid cohesion and participates in transcriptional control of genes that regulate growth and development. Substantial reduction of cohesin activity alters transcription of many genes without disrupting
Externí odkaz:
https://doaj.org/article/12378e1de09c460384bc504f26134fa3
Autor:
Bianca Lopez, Philip Yeagle, Pamela J. Hines, Jelena Stajic, Michael A. Funk, Marc S. Lavine, Leslie K. Ferrarelli, Valda Vinson, Gemma Alderton, Yevgeniya Nusinovich, Stella M. Hurtley, Phil Szuromi, Brent Grocholski, Seth Thomas Scanlon, Ifor Williams, Mattia Maroso, Dale Dorsett
Publikováno v:
Science. 377:829-830
Highlights from the Science family of journals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08bd09b7375a90b38b227a0bc6f15e60
https://doi.org/10.1126/science.ade4238
https://doi.org/10.1126/science.ade4238
Autor:
Yaning Wu, Maria Gause, Dongbin Xu, Ziva Misulovin, Cheri A Schaaf, Ramya C Mosarla, Elizabeth Mannino, Megan Shannon, Emily Jones, Mi Shi, Wen-Feng Chen, Olivia L Katz, Amita Sehgal, Thomas A Jongens, Ian D Krantz, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005655 (2015)
Individuals with Cornelia de Lange Syndrome (CdLS) display diverse developmental deficits, including slow growth, multiple limb and organ abnormalities, and intellectual disabilities. Severely-affected individuals most often have dominant loss-of-fun
Externí odkaz:
https://doaj.org/article/8f9fec2959ca49adb0fe3c3b042b0b61
Autor:
Beverly A. Purnell, Seth Thomas Scanlon, Ian S. Osborne, Jelena Stajic, Peter Stern, Valda Vinson, Pamela J. Hines, Wei Wong, Laura M. Zahn, Dale Dorsett, Andrew M. Sugden, Ifor Williams, Marc S. Lavine, Caroline Ash, Melissa Norton, Michael A. Funk
Publikováno v:
Science. 370:1177-1179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e101fe2d5700e39a40f93d03263ef901
https://doi.org/10.1126/science.2020.370.6521.twis
https://doi.org/10.1126/science.2020.370.6521.twis
Autor:
Keith T. Smith, Ian S. Osborne, Stella M. Hurtley, Pamela J. Hines, Laura M. Zahn, Leslie K. Ferrarelli, Mattia Maroso, Brent Grocholski, Gemma Alderton, Claire Olingy, Marc S. Lavine, Caroline Ash, Michael A. Funk, Peter Stern, Dale Dorsett
Publikováno v:
Science. 370:805-807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6e06c463acffa136595880cdeafa16
https://doi.org/10.1126/science.2020.370.6518.twis
https://doi.org/10.1126/science.2020.370.6518.twis
Autor:
Dale Dorsett
Publikováno v:
Trends Genet
The cohesin protein complex mediates sister chromatid cohesion to ensure accurate chromosome segregation, and also influences gene transcription in higher eukaryotes. Modest deficits in cohesin function that do not alter chromosome segregation cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37cd407d719a0aed53f384bce55a370
https://doi.org/10.1016/j.tig.2019.04.002
https://doi.org/10.1016/j.tig.2019.04.002