Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dakshina M. Jandhyala"'
Autor:
Dakshina M. Jandhyala, John Wong, Nicholas J. Mantis, Bruce E. Magun, John M. Leong, Cheleste M. Thorpe
Publikováno v:
Toxins, Vol 8, Iss 9, p 259 (2016)
Ricin activates the proinflammatory ribotoxic stress response through the mitogen activated protein 3 kinase (MAP3K) ZAK, resulting in activation of mitogen activated protein kinases (MAPKs) p38 and JNK1/2. We had a novel zak−/− mouse generated t
Externí odkaz:
https://doaj.org/article/4bf3f246dcae4e1a930a42abf4b73acb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Shiga toxin-producing Escherichia coli (STEC) can cause central nervous system (CNS) damage resulting in paralysis, seizures, and coma. The key STEC virulence factors associated with systemic illness resulting in CNS impairment are Shiga toxins (Stx)
Externí odkaz:
https://doaj.org/article/7578da6768a0429f9bd820939d7ac129
Autor:
Fumiko eObata, Priyanka B Subrahmanyam, Aimee E Vozenilek, Lauren M Hippler, Tynae eJeffers, Methinee eTongsuk, Irina eTiper, Progyaparamita eSaha, Dakshina M Jandhyala, Glynis L Kolling, Olga eLatinovic, Tonya J Webb
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Shiga toxin-producing Escherichia coli (STEC) is a leading cause of childhood renal disease He-molytic Uremic Syndrome (HUS). The involvement of renal cytokines and chemokines is sus-pected to play a critical role in disease progression. In current a
Externí odkaz:
https://doaj.org/article/08584b3abfe54eed9bef6a31c44fd8e5
Autor:
Jennifer J. Schimmel, Arlin B. Rogers, Amrita Ahluwalia, John M. Leong, Dakshina M. Jandhyala, Cheleste M. Thorpe
Publikováno v:
Infection and Immunity. 86
Infection with enterohemorrhagic Escherichia coli (EHEC) can result in severe disease, including hemorrhagic colitis and the hemolytic uremic syndrome. Shiga toxins (Stx) are the key EHEC virulence determinant contributing to severe disease. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98d6f040b6eb7a1c5f4b3e301184cb8
https://doi.org/10.1128/iai.00753-17
https://doi.org/10.1128/iai.00753-17
Autor:
Cheleste M. Thorpe, Jing Zhou, David L. Kaplan, Dakshina M. Jandhyala, Erica P. Kimmerling, Wassim El-Jouni, John M. Leong, Teresa M. DesRochers
Publikováno v:
Infection and Immunity. 83:28-38
Shiga toxins (Stx) are a family of cytotoxic proteins that can cause hemolytic-uremic syndrome (HUS), a thrombotic microangiopathy, following infections by Shiga toxin-producing Escherichia coli (STEC). Renal failure is a key feature of HUS and a maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5533435b8a5b4e34444ec98cb59f514
https://doi.org/10.1128/iai.02143-14
https://doi.org/10.1128/iai.02143-14
Autor:
John M. Leong, Vijay K. Vanguri, Beth A. McCormick, Erik J. Boll, YuShuan Lai, Dakshina M. Jandhyala
Publikováno v:
Infectious Disease Clinics of North America. 27:631-649
Pathogenic Escherichia coli are genetically diverse and encompass a broad variety of pathotypes, such as enteroaggregative E. coli (EAEC) or enterohemorrhagic E. coli (EHEC), which cause distinct clinical syndromes. The historically large 2011 German
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c0c5ade9657344146efbc7d16bdaac6
https://doi.org/10.1016/j.idc.2013.05.002
https://doi.org/10.1016/j.idc.2013.05.002
Autor:
Nicholas J. Mantis, John M. Leong, Dakshina M. Jandhyala, John B. Wong, Bruce E Magun, Cheleste M. Thorpe
Publikováno v:
Toxins, Vol 8, Iss 9, p 259 (2016)
Toxins
Toxins
Ricin activates the proinflammatory ribotoxic stress response through the mitogen activated protein 3 kinase (MAP3K) ZAK, resulting in activation of mitogen activated protein kinases (MAPKs) p38 and JNK1/2. We had a novel zak-/- mouse generated to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3cc8c6080c0f7a7790ccb06b0f802c
http://www.mdpi.com/2072-6651/8/9/259
http://www.mdpi.com/2072-6651/8/9/259
Autor:
James C. Paton, Jennifer J. Wolfson, Adrienne W. Paton, Kerrie L. May, Cheleste M. Thorpe, Dakshina M. Jandhyala
Publikováno v:
Cellular Microbiology. 10:1775-1786
Summary Subtilase cytotoxin (SubAB) is the prototype of a new family of AB5 cytotoxins produced by Shiga toxigenic Escherichia coli. Its cytotoxic activity is due to its capacity to enter cells and specifically cleave the essential endoplasmic reticu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbdb4037702a72d467d623368585b34
https://doi.org/10.1111/j.1462-5822.2008.01164.x
https://doi.org/10.1111/j.1462-5822.2008.01164.x
Autor:
Rachael C. Rigden, Brigitte Gicquel, Nicolas Lopez-Villalobos, Chris Dupont, Norihiro Maeda, Dianna Crosbie-Caird, Dakshina M. Jandhyala, Alan Murray
Publikováno v:
Journal of Medical Microbiology. 55:1735-1740
An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins. N-terminal polyhistidine-tagged P22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616c3fd16fda577340fcbe1a35315642
https://doi.org/10.1099/jmm.0.46785-0
https://doi.org/10.1099/jmm.0.46785-0
Publikováno v:
Applied Microbiology and Biotechnology. 68:327-335
Recombinant forms of three cyanide-degrading nitrilases, CynD from Bacillus pumilus C1, CynD from Pseudomonas stutzeri, and CHT from Gloeocercospora sorghi, were prepared after their genes were cloned with C-terminal hexahistidine purification tags a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08841f3acc4558edce6a4870f4090ee
https://doi.org/10.1007/s00253-005-1903-8
https://doi.org/10.1007/s00253-005-1903-8