Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dakota Ma"'
Autor:
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Gengfu Xiao, Zihe Rao, Lu Lu, Leike Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Respiratory disease caused by coronavirus infection remains a global health crisis. Although several SARS-CoV-2-specific vaccines and direct-acting antivirals are available, their efficacy on emerging coronaviruses in the future, including S
Externí odkaz:
https://doaj.org/article/ed0f8030dd354143aa36edeafd04c36b
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT While endocytic and secretory pathways are well-studied cellular processes in the model yeast Saccharomyces cerevisiae, they remain understudied in the opportunistic fungal pathogen Candida albicans. We previously found that null mutants of
Externí odkaz:
https://doaj.org/article/e7f3e7a223ba4c7eb2365736afd9866d
Publikováno v:
Journal of Fungi, Vol 9, Iss 11, p 1097 (2023)
The endocytic and secretory pathways of the fungal pathogen Candida albicans are fundamental to various key cellular processes such as cell growth, cell wall integrity, protein secretion, hyphal formation, and pathogenesis. Our previous studies focus
Externí odkaz:
https://doaj.org/article/2df6eb0e2cd242a4943735e835827b85
Publikováno v:
Journal of Fungi, Vol 6, Iss 1, p 26 (2020)
Candida albicans is a fungus that is a commensal organism and a member of the normal human microbiota. It has the ability to transition into an opportunistic invasive pathogen. Attributes that support pathogenesis include secretion of virulence-assoc
Externí odkaz:
https://doaj.org/article/81d73ed56a4f4b22a6c9ffc88a02ac9e
Autor:
Xiong Xie, Yu-Gui Zheng, Huan Chen, Jian Li, Rong-Hua Luo, Liang Chen, Chang-Bo Zheng, Shurui Zhang, Panfeng Peng, Dakota Ma, Liu-Meng Yang, Yong-Tang Zheng, Hong Liu, Jiang Wang
Publikováno v:
Journal of medicinal chemistry. 65(24)
Blocking the entry of an HIV-1 targeting CCR5 coreceptor has emerged as an attractive strategy to develop HIV therapeutics. Maraviroc is the only CCR5 antagonist approved by FDA; however, serious side effects limited its clinical use. Herein, 21 nove
Autor:
Sahil Mamtani, Reva Dixit, Dakota Ma, Samuel A Lee, Christiane Rollenhagen, Susan K. Eszterhas
Publikováno v:
Journal of Fungi
Journal of Fungi, Vol 6, Iss 1, p 26 (2020)
Journal of Fungi, Vol 6, Iss 1, p 26 (2020)
Candida albicans is a fungus that is a commensal organism and a member of the normal human microbiota. It has the ability to transition into an opportunistic invasive pathogen. Attributes that support pathogenesis include secretion of virulence-assoc
Autor:
Shuangjie Shu, Dehua Yang, Dakota Ma, Ming-Wei Wang, Yang Feng, Xiaoqing Cai, Bin Wang, Jia Li, Hong Liu, Jiang Wang, Antao Dai
Publikováno v:
Bioorganicmedicinal chemistry. 26(8)
A novel series of 4-methyl substituted pyrazole derivatives were designed, synthesized and biologically evaluated as potent glucagon receptor (GCGR) antagonists. In this study, compounds 9q, 9r, 19d and 19e showed high GCGR binding (IC50 = 0.09 μM,
Autor:
Dakota Ma, Xiaoqing Cai, Yang Feng, Huihui Li, Ming-Wei Wang, Jia Li, Hong Liu, Shuangjie Shu, Jiang Wang, Antao Dai, Dehua Yang
Publikováno v:
Chemical biologydrug design. 92(1)
A novel series of thiophene-containing biaryl amide glucagon receptor (GCGR) antagonists were designed and synthesized. Two compounds of this series, 14f and 14h, exhibited good GCGR binding (IC50 = 6.1 and 4.4 μm, respectively) and cAMP functional
Autor:
Rollenhagen, Christiane, Mamtani, Sahil, Dakota Ma, Dixit, Reva, Eszterhas, Susan, Lee, Samuel A.
Publikováno v:
Journal of Fungi; Mar2020, Vol. 6 Issue 1, p1-37, 37p
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Use of face coverings has been shown to reduce transmission of SARS-CoV-2. Despite encouragements from the CDC and other public health entities, resistance to usage of masks remains, forcing government entities to create mandates to compel use. The s
Externí odkaz:
https://doaj.org/article/8d19cda4d7d24bd8bd7c69b6445ebccd