Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dakota L. Grote"'
Autor:
Tapiwa Chiura, Amanda J. Mitchell, Dakota L. Grote, Niloufar Khojandi, Ryan M. Teague, Piotr J. Mak
Publikováno v:
Journal of Inorganic Biochemistry. 244:112238
Autor:
Chanté Muller, Dakota L. Grote, R.L. Walter, James R. Horn, James L. Gorman, Timothy J. Hagen, Gina Ranieri, Joy M. Blain, Heike Hofstetter, Gashaw M. Goshu, Sydney M. Watkins
Publikováno v:
Bioorg Med Chem Lett
The enzyme 2-methylerythritol 2,4-cyclodiphosphate synthase, IspF, is essential for the biosynthesis of isoprenoids in most bacteria, some eukaryotic parasites, and the plastids of plant cells. The development of inhibitors that target IspF may lead
Autor:
Dakota L. Grote, James R. Horn, Debarati Ghose, R. Meganathan, Sydney M. Watkins, Joy M. Blain, Timothy J. Hagen, Chi Hao Luan, Michael Clare
Publikováno v:
Bioorg Med Chem Lett
Enzymes in the methylerythritol phosphate pathway make attractive targets for antibacterial activity due to their importance in isoprenoid biosynthesis and the absence of the pathway in mammals. The fifth enzyme in the pathway, 2-C-methyl-d-erythrito