Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dakota F. Brockway"'
Autor:
Dakota F. Brockway, Keith R. Griffith, Chloe M. Aloimonos, Thomas T. Clarity, J. Brody Moyer, Grace C. Smith, Nigel C. Dao, Md Shakhawat Hossain, Patrick J. Drew, Joshua A. Gordon, David A. Kupferschmidt, Nicole A. Crowley
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112976- (2023)
Summary: We sought to characterize the unique role of somatostatin (SST) in the prelimbic (PL) cortex in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to characterize the pharmacological mechanism of SST signaling and
Externí odkaz:
https://doaj.org/article/6d6c0587838643a4b9fa5f7bc88a9bac
Autor:
Malini Suresh Nair, Nigel C. Dao, Daniela Lopez Melean, Keith R. Griffith, W. David Starnes, J. Brody Moyer, Avery R. Sicher, Dakota F. Brockway, Kathleen D. Meeks, Nicole A. Crowley
Publikováno v:
Brain Research Bulletin, Vol 186, Iss , Pp 38-46 (2022)
Alcohol use disorder (AUD) is characterized by alcohol use coupled with chronic relapse and involves brain regions including the bed nucleus of the stria terminalis (BNST). Here, we explore whether a subpopulation of BNST neurons, somatostatin (SST)
Externí odkaz:
https://doaj.org/article/c4aa9d521b2741089088b22458199128
Autor:
Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Recent advancements in technology have enabled researchers to probe the brain with the greater region, cell, and receptor specificity. These developments have allowed for a more thorough understanding of how regulation of the neurophysiology within a
Externí odkaz:
https://doaj.org/article/2c2df92fa07f4cb89010d3171ae52247
Autor:
Nigel C. Dao, Malini Suresh Nair, Sarah N. Magee, J. Brody Moyer, Veronica Sendao, Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Forced abstinence (FA) from alcohol has been shown to produce a variety of anxiety- and depression-like symptoms in animal models. Somatostatin (SST) neurons, a subtype of GABAergic neurons found throughout the brain, are a novel neural target with p
Externí odkaz:
https://doaj.org/article/1cbcd53b708d43639d7355019f7205b7
Autor:
Avery R. Sicher, William D. Starnes, Keith R. Griffith, Nigel C. Dao, Grace C. Smith, Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Neuropharmacology. 234:109561
Adolescent drug consumption has increased risks to the individual compared to consumption in adulthood, due to the likelihood of long-term and permanent behavioral and neurological adaptations. However, little is known about how adolescent alcohol co
Publikováno v:
Neuropsychopharmacology. 46:1906-1917
Somatostatin (SST) neurons have been implicated in a variety of neuropsychiatric disorders such as depression and anxiety, but their role in substance use disorders, including alcohol use disorder (AUD), is not fully characterized. Here, we found tha
Autor:
Dakota F Brockway, Keith R Griffith, Chloe M Aloimonos, Thomas Clarity, Jacob Brody Moyer, Grace C Smith, Nigel C Dao, Md Shakhawat Hossain, Patrick J. Drew, Joshua A Gordon, David A Kupferschmidt, Nicole A Crowley
Somatostatin (SST) neurons in the prelimbic (PL) cortex mediate a variety of behavioral states. However, little is known about the actions of somatostatin peptide signaling in shaping cortical functioning and behavior. Here, we sought to characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056bb1cee0cf62588c9431b26c1fdcb1
https://doi.org/10.1101/2022.07.18.499817
https://doi.org/10.1101/2022.07.18.499817
Somatostatin neurons have been implicated in a variety of neuropsychiatric disorders such as depression and anxiety, but their role in substance abuse disorders, including alcohol use disorder (AUD), is not fully characterized. Here we found that rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e371ed376b4002e9863a7417e450b0
https://doi.org/10.1101/2020.11.27.400465
https://doi.org/10.1101/2020.11.27.400465
Publikováno v:
Neuroscience. 419
Somatostatin is a neuropeptide thought to play a role in a variety of neuropsychiatric disorders, and is important for healthy aging and behavioral resiliency. Physiological conditions underlying somatostatin peptidergic release are not well-defined.
Publikováno v:
Cancer Research. 80:2972-2972
Glioblastoma multiforme is one of the most common and malignant tumors of the central nervous system, remaining incurable with a median survival time of only 15 months. Over the past 50 years there has been little change in this overall survival rate