Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Dakota B. Zinani"'
1
Akademický článek
SCH23390 and a humanized anti-cocaine mAb decrease the latency to cocaine-induced reinstatement of lever pressing behavior in rats that self-administer cocaine
Autor: Dakota B. Zinani, Jhanvi N. Desai, Andrew B. Norman
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract In rats that self-administer cocaine, the latency to the reinstatement of lever pressing behavior induced by a single dose of cocaine is due to the time taken for cocaine levels to fall to the satiety threshold. The D1 dopamine receptor anta
Externí odkaz: https://doaj.org/article/de1a3376fc14486db11a0d4898f9b30a
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2
Akademický článek
The cocaine compulsion zone theory explains the reinstatement of lever pressing behavior in rats in response to a single cocaine dose
Autor: Dakota B. Zinani, Jhanvi N. Desai, Andrew B. Norman
Publikováno v: Heliyon, Vol 9, Iss 7, Pp e17988- (2023)
A single non-contingent dose of cocaine reinstates extinguished lever pressing behavior in rats trained to self-administer cocaine. This represents a model of relapse in cocaine use disorder and the number of lever presses has been the standard measu
Externí odkaz: https://doaj.org/article/b5a0d9e4b135485186615f36c049b241
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3
Akademický článek
Effects of a recombinant humanized anti‐cocaine monoclonal antibody on the metabolism and distribution of cocaine in vitro and in mice
Autor: Mackenzie E. Turner, Hanna N. Wetzel, Dakota B. Zinani, Christopher A. Crutchfield, Andrew B. Norman
Publikováno v: Pharmacology Research & Perspectives, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract The anti‐cocaine monoclonal antibody, h2E2, is a candidate for treating cocaine‐use disorder. h2E2 binds to and sequesters cocaine in the plasma compartment, effectively decreasing cocaine concentrations in the brains of rats and mice. D
Externí odkaz: https://doaj.org/article/dee88af421da49db8c47c107362dd31d
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7
The compulsion zone explains the self-administration of cocaine, RTI-55 and bupropion in rats
Autor: Dakota B. Zinani, Hanna N. Wetzel, Andrew B. Norman
Publikováno v: Brain Research. 1774:147707
Rats that reliably self-administered cocaine also reliably self-administered the cocaine analog RTI-55 and bupropion. The inter-injection intervals of these dopamine transporter (DAT) inhibitors were regular at a given unit dose and increased as a fu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb01af2e85f48060c28b34654e15f1c5
https://doi.org/10.1016/j.brainres.2021.147707
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