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pro vyhledávání: '"Dakota B. Ward"'
Radiocontrast Agent Diatrizoic Acid Induces Mitophagy and Oxidative Stress via Calcium Dysregulation
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4074 (2019)
Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital associated kidney damage. Potential mechanisms of CI-AKI may involve diminished renal hemodynamics, inflammatory responses, and direct cytotoxicity. The hypothes
Externí odkaz:
https://doaj.org/article/dba490767f474dd6a0cdaf88dbda7877
Autor:
Monica A. Valentovic, Dakota B. Ward
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:160-171
The administration of intravenous iodinated radiocontrast media (RCM) to visualize internal structures during diagnostic procedures has increased exponentially since their first use in 1928. A serious side effect of RCM exposure is contrast-induced a
Autor:
Dakota B. Ward, Monica A. Valentovic, Dianne K. Anestis, Gary O. Rankin, John G. Ball, Debbie Preston, Christopher Racine, Travis Ferguson
Publikováno v:
Toxicology. :47-55
Among the mono- and dichloroanilines, 3,5-Dichloroaniline (3,5-DCA) is the most potent nephrotoxicant in vivo and in vitro. However, the role of renal biotransformation in 3,5-DCA induced nephrotoxicity is unknown. The current study was designed to d
Autor:
Travis Ferguson, Dakota B. Ward, Christopher Racine, Gary O. Rankin, Dianne K. Anestis, Deborah L. Preston
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20900-20912 (2014)
Volume 15
Issue 11
Pages 20900-20912
International Journal of Molecular Sciences, Vol 15, Iss 11, Pp 20900-20912 (2014)
Volume 15
Issue 11
Pages 20900-20912
Chloroanilines are widely used in the manufacture of drugs, pesticides and industrial intermediates. Among the trichloroanilines, 3,4,5-trichloroaniline (TCA) is the most potent nephrotoxicant in vivo. The purpose of this study was to examine the nep