Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dakka, Jumana"'
Autor:
Dakka, Jumana, Farkas-Pall, Kristof, Turilli, Matteo, Wright, David W, Coveney, Peter V, Jha, Shantenu
The efficacy of drug treatments depends on how tightly small molecules bind to their target proteins. The rapid and accurate quantification of the strength of these interactions (as measured by binding affinity) is a grand challenge of computational
Externí odkaz:
http://arxiv.org/abs/1801.01174
Autor:
Dakka, Jumana, Turilli, Matteo, Wright, David W, Zasada, Stefan J, Balasubramanian, Vivek, Wan, Shunzhou, Coveney, Peter V, Jha, Shantenu
Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily se
Externí odkaz:
http://arxiv.org/abs/1712.09168
Autor:
Dakka, Jumana, Bashivan, Pouya, Gheiratmand, Mina, Rish, Irina, Jha, Shantenu, Greiner, Russell
Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning studies use h
Externí odkaz:
http://arxiv.org/abs/1712.00512
Autor:
Roy, Bijoyita, Friesen, Westley J., Tomizawa, Yuki, Leszyk, John D., Zhuo, Jin, Johnson, Briana, Dakka, Jumana, Trotta, Christopher R., Xue, Xiaojiao, Mutyam, Venkateshwar, Keeling, Kim M., Mobley, James A., Rowe, Steven M., Bedwell, David M., Welch, Ellen M., Jacobson, Allan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Nov 01. 113(44), 12508-12513.
Externí odkaz:
https://www.jstor.org/stable/26472308
Autor:
Dakka, Jumana1 jumana.dakka@rutgers.edu, Turilli, Matteo1 matteo.turilli@rutgers.edu, Wright, David W.2 dave.wright@ucl.ac.uk, Zasada, Stefan J.2 stefan.zasada@ucl.ac.uk, Balasubramanian, Vivek1 vivek.balasubramanian@rutgers.edu, Wan, Shunzhou2 shunzhou.wan@ucl.ac.uk, Coveney, Peter V.2 p.v.coveney@ucl.ac.uk, Jha, Shantenu1,3,4 shantenu.jha@rutgers.edu
Publikováno v:
BMC Bioinformatics. 12/21/2018 Supplement 18, Vol. 19 Issue 18, p33-45. 13p. 1 Color Photograph, 3 Diagrams, 1 Chart, 2 Graphs.
Autor:
Dakka, Jumana
Free energy calculations that use molecular dynamics (MD) simulations are emerg- ing as an important tool for studying important problems like computational drug de- sign. Recent evidence suggests that free energy calculations, specifically binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91dfbcf0c0bf6dc173231c66a894ec27
Autor:
Phan, Timothy S., Dakka, Jumana, Syed, Amer Ahmed, Vasim, Izzah, Oldland, Harry G., Kewan, Uzma, Akers, Scott R., Chirinos, Julio A.
Publikováno v:
In Journal of the American College of Cardiology 21 March 2017 69(11) Supplement:1729-1729
Autor:
Dakka, Jumana, Phan, Timothy S., Vasim, Izzah, Varakantam, Swapna, Kewan, Uzma, Tariq, Ali, Oldland, Harry G., Syed, Amer Ahmed, Hashmath, Zeba, Akers, Scott R., Chirinos, Julio A.
Publikováno v:
In Artery Research December 2016 16:96-97
Autor:
'Dakka, Jumana
Publikováno v:
Farkas-Pall, Kristof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::1ce9e18aa03b4f4b9d4afce240514f4a
Autor:
Dakka, Jumana, Turilli, Matteo, Wright, David W., Zasada, Stefan J., Balasubramanian, Vivek, Wan, Shunzhou, Coveney, Peter V., Jha, Shantenu
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S18, Pp 33-45 (2018)
BMC Bioinformatics
BMC Bioinformatics
Background Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e641cb83165573d8c06da64cb3c29bbe