Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial

Autor: Gorrie, George, Morrison, Ian, Duncan, Callum, Carod Artal, Javier, Williams, Timothy, Srinivasan, Venkataramanan, Radunovic, Aleksandar, Pinto, Ashwin, Hamdalla, Hisham, Roberts, Rhys, Garcia- Reitboeck, Pablo, Harrower, Timothy, Mamutse, Godwin, Crawley, Francesca, Galton, Clare, Dawson, Kenneth, Forbes, Raeburn, Hillier, Charles, McDermott, Christopher, Forbes, Deborah, Bozkurt, Hatice, Stavrou, Maria, Kearns, Patrick, Breen, David, Kurucu King, Hatice, Elliot, Elizabeth, Beswick, Emily, Williamson, Jill, Cucurachi, Paolo, McLennan, Lucy, Pal, Suvankar ^{a, b, c, d, g, i, *}, Chataway, Jeremy ^{g, h, i, l}, Swingler, Robert ^j, Macleod, Malcolm R ^{c, i}, Carragher, Neil O ^f, Hardingham, Giles ^d, Selvaraj, Bhuvaneish Thangaraj ^{a, b, c, d}, Smith, Colin ^{a, c}, Wong, Charis ^{a, b, c, g}, Newton, Judith ^{a, b, c, i}, Lyle, Dawn ^{a, b, c}, Stenson, Amy ^{a, b, c, i}, Dakin, Rachel S ^{a, b, c}, Ihenacho, Amarachi ^{a, b, c}, Colville, Shuna ^{a, b, c}, Mehta, Arpan R ^{a, b, c, i, n}, Stallard, Nigel ^k, Carpenter, James R ^{g, i}, Parker, Richard A ^{e, i}, Keerie, Catriona ^e, Weir, Christopher J ^{e, g, i}, Virgo, Bruce ^m, Morris, Stevie ^m, Waters, Nicola ^m, Gray, Beverley ^m, MacDonald, Donald ^m, MacDonald, Euan ^{m, †}, Parmar, Mahesh K B ^{g, i}, Chandran, Siddharthan ^{a, b, c, d, g, i}

Publikováno v: In The Lancet Neurology November 2024 23(11):1097-1107

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Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector

Autor: Dakin, Rachel S., Parker, Alan L., Delles, Christian, Nicklin, Stuart A., Baker, Andrew H.

Publikováno v: Human Gene Therapy

Neointima formation and vascular remodeling through vascular smooth muscle cell migration and proliferation can limit the long-term success of coronary interventions, for example, in coronary artery bypass grafting (CABG). Ex vivo gene therapy has th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::583406c703dc12a3e6ef0d5b58acc246
https://eprints.gla.ac.uk/103867/7/103867.pdf

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