Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dajana Lichtenstein"'
Autor:
Ahmed S.M. Ali, Dongwei Wu, Alexandra Bannach-Brown, Diyal Dhamrait, Johanna Berg, Beatrice Tolksdorf, Dajana Lichtenstein, Corinna Dressler, Albert Braeuning, Jens Kurreck, Maren Hülsemann
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 100991- (2024)
Background: Effective communication is crucial for broad acceptance and applicability of alternative methods in 3R biomedical research and preclinical testing. 3D bioprinting is used to construct intricate biological structures towards functional liv
Externí odkaz:
https://doaj.org/article/05f4e10abd16459a862236c8c2292b50
Autor:
Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, Kristin Schubert, Ola Spjuth, Evelyn Stinckens, Kathrin Thedieck, Rik van den Boom, Lucia Vergauwen, Martin von Bergen, Neele Wewer, Daniel Zalko
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Externí odkaz:
https://doaj.org/article/c83d238d04114c37b33e13818a71f8db
Autor:
Mawien Karaca, Kristin Fritsche, Dajana Lichtenstein, Özlem Vural, Katrin Kreuzer, Jimmy Alarcan, Albert Braeuning, Philip Marx-Stoelting, Tewes Tralau
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102500- (2023)
Summary: Here, we present an in vitro test battery to analyze chemicals for their potential to induce liver triglyceride accumulation, a hallmark of liver steatosis. We describe steps for using HepG2 and HepaRG human hepatoma cells in conjunction wit
Externí odkaz:
https://doaj.org/article/c3abcaf3af90457daa1ba47d60a00cb4
Autor:
Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, Kristin Schubert, Ola Spjuth, Evelyn Stinckens, Kathrin Thedieck, Rik van den Boom, Lucia Vergauwen, Martin von Bergen, Neele Wewer, Daniel Zalko
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
In past times, the analysis of endocrine disrupting properties of chemicals has mainly been focused on (anti-)estrogenic or (anti-)androgenic properties, as well as on aspects of steroidogenesis and the modulation of thyroid signaling. More recently,
Externí odkaz:
https://doaj.org/article/7ee7a592f1ad4eba98f91899309c0cf9
Autor:
Linda Böhmert, Laura König, Holger Sieg, Dajana Lichtenstein, Niklas Paul, Albert Braeuning, Andreas Voigt, Alfonso Lampen
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-20 (2018)
Abstract Background Even though a continuously high number of in vitro studies on nanoparticles are being published, the issue of correct dose matter is often not sufficiently taken into account. Due to their size, the diffusion of nanoparticles is s
Externí odkaz:
https://doaj.org/article/199c307025e943aa80a657cc48da451e
Autor:
Jimmy Alarcan, Dajana Lichtenstein, R. Rahmani, Kyriaki Machera, Albert Braeuning, Alfonso Lampen, Petros Batakis, Anastasia Spyropoulou, Georges de Sousa, Efrosini S. Katsanou
Publikováno v:
Archives of Toxicology
Within the EuroMix project, we have previously developed an adverse outcome pathway (AOP)-based in vitro assay toolbox to investigate the combined effects of liver steatosis-inducing compounds in human HepaRG hepatocarcinoma cells. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae02a1d5ed4eac89595faf01f241b37
https://doi.org/10.1007/s00204-021-03182-1
https://doi.org/10.1007/s00204-021-03182-1
Publikováno v:
Archives of Toxicology
The liver is constantly exposed to mixtures of hepatotoxic compounds, such as food contaminants and pesticides. Dose addition is regularly assumed for mixtures in risk assessment, which however might not be sufficiently protective in case of synergis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b541e49e2c61fc4be42189f339df562
https://doi.org/10.1007/s00204-021-02997-2
https://doi.org/10.1007/s00204-021-02997-2
Autor:
Jimmy Alarcan, Albert Braeuning, Claudia Luckert, Alfonso Lampen, Philip Marx-Stoelting, Heike Sprenger, Dajana Lichtenstein, Julia Waizenegger
Publikováno v:
Archives of Toxicology
Co-occurrence of pesticide residues in food commodities raises a potential safety issue as their mixture effects on human health are largely unknown. In a previous study, we reported the toxicological effects (pathology and histopathology) of imazali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e0504d2419bd1c295b874359dbd12a
http://europepmc.org/articles/PMC7904562
http://europepmc.org/articles/PMC7904562
Autor:
Yamina El Hamdaoui, Fang Zheng, Nikolas Fritz, Lian Ye, Mai Anh Tran, Kevin Schwickert, Tanja Schirmeister, Albert Braeuning, Dajana Lichtenstein, Ute A. Hellmich, Dorothee Weikert, Markus Heinrich, Giulia Treccani, Michael K. E. Schäfer, Gabriel Nowak, Bernd Nürnberg, Christian Alzheimer, Christian P. Müller, Kristina Friedland
St. John’s wort is an herb, long used in folk medicine for the treatment of mild depression. Its antidepressant constituent, hyperforin, has properties such as chemical instability and induction of drug-drug interactions that preclude its use for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8bc642bc19d371657714dc5545fd48
https://ruj.uj.edu.pl/xmlui/handle/item/304115
https://ruj.uj.edu.pl/xmlui/handle/item/304115
Autor:
Alfonso Lampen, Dajana Lichtenstein, Julia Cara-Carmona, Valerie Stock, Rafael Block, Albert Braeuning, Laura Kim Pack, Holger Sieg, Colin J. Henderson, Elisa Lisicki, Elke Zabinsky, Linda Böhmert, Regina Selb, Linn Voss
Publikováno v:
Archives of Toxicology. 93:1817-1833
Evidence exists that humans are exposed to plastic microparticles via diet. Data on intestinal particle uptake and health-related effects resulting from microplastic exposure are scarce. Aim of the study was to analyze the uptake and effects of micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afc75bd4bab740c4288cb39d8e7dafc
https://doi.org/10.1007/s00204-019-02478-7
https://doi.org/10.1007/s00204-019-02478-7