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pro vyhledávání: '"Daiwei Shen"'
Publikováno v:
Human Genetics. 97:720-722
The human RGR gene encodes an opsin protein (retinal G protein-coupled receptor), which is expressed in Müller cells and the retinal pigment epithelium and is thought to play a role in the visual process. To investigate a possible linkage of the RGR
Autor:
Pu Chen, L. Rife, Wenshan Hao, Thomas E. Ogden, Jeannie Chen, Gretchen B. Van Boemel, Daiwei Shen, Lanyin Wu, Henry K.W. Fong, Mao Yang, Xiao Peng Wang
Publikováno v:
Nature genetics. 28(3)
During visual excitation, rhodopsin undergoes photoactivation and bleaches to opsin and all-trans-retinal1,2. To regenerate rhodopsin and maintain normal visual sensitivity, the all-trans isomer must be metabolized and reisomerized to produce the chr
Publikováno v:
Experimental eye research. 60(4)
An opsin-related gene encodes a putative RPE-retinal G-protein-coupled receptor (RGR) that is most homologous to the visual pigments and invertebrate retinochrome. A splice variant of human RGR mRNA can be demonstrated by the sequence of isolated cDN
Publikováno v:
Biochemistry. 33(44)
The ligand-binding property of a cytoplasmic membrane-bound protein from bovine retinal pigment epithelium (RPE) has been demonstrated. The putative RPE-retinal G protein coupled receptor (RGR) covalently binds both all-trans- and 11-cis-retinal afte