Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Daisy Yuill"'
Publikováno v:
Bioanalysis. 13(21)
As the number of therapeutic modalities expand, and the field of scientific research evolves toward finding treatment solutions for complex and rare disease, an ability to demonstrate efficacy through biomarker end points in clinical development stud
Autor:
Andrea Martín-Nalda, Maria Juarez, Pere Soler-Palacín, Francesca Conti, Eric Helmer, Caterina Cancrini, Geoffrey I Johnston, Marina Cavazzana, Dionne Cain, Nieves Diaz, Marina Garcia-Prat, Despina Moshous, Maria Elena Maccari, Payne Andrew Charles, Felipe Suarez, Michaela Semeraro, Sven Kracker, Mónica Martínez-Gallo, Daisy Yuill, Silvia Di Cesare, Stephan Ehl, Maximilian Heeg, Joanne Mann, Alessandra Simonetti, Veronica Santilli
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, pp.ji2000326. ⟨10.4049/jimmunol.2000326⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, pp.ji2000326. ⟨10.4049/jimmunol.2000326⟩
Mutations in two genes can result in activated PI3Kδ syndrome (APDS), a rare immunodeficiency disease with limited therapeutic options. Seletalisib, a potent, selective PI3Kδ inhibitor, was evaluated in patients with APDS1 and APDS2. In the phase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc73e827abe52aed5e58c98afe06cda8
https://hal.archives-ouvertes.fr/hal-03009789/document
https://hal.archives-ouvertes.fr/hal-03009789/document