Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Daisy Sproviero"'
Autor:
Sander Barnhoorn, Chiara Milanese, Tracy Li, Lieke Dons, Mehrnaz Ghazvini, Martina Sette, Stefania Farina, Daisy Sproviero, Cesar Payan-Gomez, Pier G. Mastroberardino
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-11 (2024)
Abstract The etiopathology of Parkinson’s disease has been associated with mitochondrial defects at genetic, laboratory, epidemiological, and clinical levels. These converging lines of evidence suggest that mitochondrial defects are systemic and ca
Externí odkaz:
https://doaj.org/article/62672389eaaa4e0ba7de59e89c029fb3
Autor:
Daisy Sproviero, Stella Gagliardi, Susanna Zucca, Maddalena Arigoni, Marta Giannini, Maria Garofalo, Valentina Fantini, Orietta Pansarasa, Micol Avenali, Matteo Cotta Ramusino, Luca Diamanti, Brigida Minafra, Giulia Perini, Roberta Zangaglia, Alfredo Costa, Mauro Ceroni, Raffaele A. Calogero, Cristina Cereda
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectivesThere is a lack of effective biomarkers for neurodegenerative diseases (NDs) such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia. Extracellular vesicle (EV) RNA cargo
Externí odkaz:
https://doaj.org/article/f8553c4ef248406a902687b6a84b128f
Autor:
Maria Garofalo, Stella Gagliardi, Susanna Zucca, Cecilia Pandini, Francesca Dragoni, Daisy Sproviero, Orietta Pansarasa, Tino Emanuele Poloni, Valentina Medici, Annalisa Davin, Silvia Damiana Visonà, Matteo Moretti, Antonio Guaita, Mauro Ceroni, Livio Tronconi, Cristina Cereda
Publikováno v:
Data in Brief, Vol 38, Iss , Pp 107432- (2021)
Since the association of SARS-Cov-2 infection with Nervous System (NS) manifestations, we performed RNA-sequencing analysis in Frontal Cortex of COVID-19 positive or negative individuals and affected or not by Dementia individuals. We examined gene e
Externí odkaz:
https://doaj.org/article/8b4f5c83d9e34ba9ab3b3d0696616b8e
Autor:
Jessica Garau, Silvia Masnada, Francesca Dragoni, Daisy Sproviero, Federico Fogolari, Stella Gagliardi, Giana Izzo, Costanza Varesio, Simona Orcesi, Pierangelo Veggiotti, Gian Vincenzo Zuccotti, Orietta Pansarasa, Davide Tonduti, Cristina Cereda
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aicardi–Goutières Syndrome (AGS) is a rare disorder characterized by neurological and immunological signs. In this study we have described a child with a phenotype consistent with AGS carrying a novel compound heterozygous mutation in RNASEH2B gen
Externí odkaz:
https://doaj.org/article/bfb8e9e1e61240c6ac4979c64f0ecdd5
Autor:
Marta Giannini, Aleix Bayona-Feliu, Daisy Sproviero, Sonia I Barroso, Cristina Cereda, Andrés Aguilera
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009260 (2020)
TDP-43 is a DNA and RNA binding protein involved in RNA processing and with structural resemblance to heterogeneous ribonucleoproteins (hnRNPs), whose depletion sensitizes neurons to double strand DNA breaks (DSBs). Amyotrophic Lateral Sclerosis (ALS
Externí odkaz:
https://doaj.org/article/d695da3ae0b64c96911d89211d59eced
Autor:
Elena Casarotto, Daisy Sproviero, Eleonora Corridori, Maria Cristina Gagliani, Marta Cozzi, Marta Chierichetti, Riccardo Cristofani, Veronica Ferrari, Mariarita Galbiati, Francesco Mina, Margherita Piccolella, Paola Rusmini, Barbara Tedesco, Stella Gagliardi, Katia Cortese, Cristina Cereda, Angelo Poletti, Valeria Crippa
Publikováno v:
Cells, Vol 11, Iss 3, p 516 (2022)
Extracellular vesicles (EVs) play a central role in neurodegenerative diseases (NDs) since they may either spread the pathology or contribute to the intracellular protein quality control (PQC) system for the cellular clearance of NDs-associated prote
Externí odkaz:
https://doaj.org/article/f0766de65e1645b5997619601be9973c
Autor:
Maria Garofalo, Cecilia Pandini, Matteo Bordoni, Emanuela Jacchetti, Luca Diamanti, Stephana Carelli, Manuela Teresa Raimondi, Daisy Sproviero, Valeria Crippa, Serena Carra, Angelo Poletti, Orietta Pansarasa, Stella Gagliardi, Cristina Cereda
Publikováno v:
Cells, Vol 11, Iss 2, p 293 (2022)
Superoxide dismutase 1 (SOD1) is one of the causative genes associated with amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder. SOD1 aggregation contributes to ALS pathogenesis. A fraction of the protein is localized in the nucleus (nS
Externí odkaz:
https://doaj.org/article/1437d520abca4bdd934e90a5bd0542ca
Autor:
Daisy Sproviero, Sabrina La Salvia, Federico Colombo, Susanna Zucca, Orietta Pansarasa, Luca Diamanti, Alfredo Costa, Luca Lova, Marta Giannini, Stella Gagliardi, Eliana Lauranzano, Michela Matteoli, Mauro Ceroni, Andrea Malaspina, Cristina Cereda
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The lack of biomarkers in Amyotrophic Lateral Sclerosis (ALS) makes it difficult to determine the stage of the disease in patients and, therefore, it delays therapeutic trials. Microvesicles (MVs) are possible biomarkers implicated in physiological a
Externí odkaz:
https://doaj.org/article/7f2193b7619e4891b18e753a21d724ed
Autor:
Daisy Sproviero, Sabrina La Salvia, Marta Giannini, Valeria Crippa, Stella Gagliardi, Stefano Bernuzzi, Luca Diamanti, Mauro Ceroni, Orietta Pansarasa, Angelo Poletti, Cristina Cereda
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Amyotrophic lateral sclerosis (ALS) is a progressive adult-onset neurodegenerative disease, that affects cortical, bulbar and spinal motor neurons, and it is considered a proteinopathy, in which pathological proteins (SOD1, TDP-43, and FUS) may accum
Externí odkaz:
https://doaj.org/article/379cbefa84374363b4d69f114851a77b
Autor:
Orietta Pansarasa, Matteo Bordoni, Lorenzo Drufuca, Luca Diamanti, Daisy Sproviero, Rosa Trotti, Stefano Bernuzzi, Sabrina La Salvia, Stella Gagliardi, Mauro Ceroni, Cristina Cereda
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 3 (2018)
In the past, amyotrophic lateral sclerosis (ALS) has been considered a ‘neurocentric’ disease; however, new evidence suggests that it should instead be looked at from a ‘multisystemic’ or ‘non-neurocentric’ point of view. From 2006, we fo
Externí odkaz:
https://doaj.org/article/aa3dd1600bc747b4aff35dea120a91ac