Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daisy Manish Shah"'
Autor:
Satyawan Jadhav, Sanjay Deshmukh, Siddharth Mhatre, Abhay Kulkarni, Shital Tondlekar, Samitabh Chakraborti, Nagarajan Muthukaman, Macchindra Tambe, Dnyandeo Pisal, Vikram Mansingh Bhosale, Neelam Sarode, Daisy Manish Shah, Mahamad Yunnus A. Mahat, Girish S. Gudi, Neelima Khairatkar-Joshi, Laxmikant Atmaram Gharat
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:3766-3773
Endogenous nitrosothiols (SNOs) including S-nitrosoglutathione (GSNO) serve as reservoir for bioavailable nitric oxide (NO) and mediate NO-based signaling, inflammatory status and smooth muscle function in the lung. GSNOR inhibition increases pulmona
Autor:
Rambabu Pattem, Rajni R. Thakur, Srinivas Kummari, Neelima Khairatkar-Joshi, Ratika S. Sapalya, Satyawan Jadhav, Abraham Thomas, Praveen Kumar Gupta, Vijay Eknath Rathi, Ajit Shankar Mindhe, V. S. Prasadarao Lingam, Srinivas Gullapalli, Yogesh B. Shingote, Malini Bajpai, Girish S. Gudi, Daisy Manish Shah, Dnyaneshwar Harishchandra Dahale
Publikováno v:
Journal of medicinal chemistry. 58(20)
We report the design and synthesis of novel 5,6-diarylated pyridin-2(1H)-one derivatives as pharmacophoric PDE10A inhibitors. This highly potent molecular scaffold was developed from an inactive diarylpyridine-2-amine derivative 3b by extensive and s
Autor:
Sachin Sundarlal Chaudhari, Abraham Thomas, Daisy Manish Shah, Satyawan Jadhav, Malini Bajpai, Srinivasa Honnegowda, Neelima Khairatkar-Joshi, Sanjib Das, Abhay Kulkarni, Girish S. Gudi, Indrani Sarkar
Publikováno v:
5.1 Airway Pharmacology and Treatment.
Background: Antibody mediated IL-17 blockade is remarkably successful in autoimmune disease treatment. Recent studies implicate IL-17 in airway diseases. Increased IL-17 immuno-reactivity and Th17 cells in lung tissue and IL-17 level in bronchoalveol
Autor:
Abraham Thomas, Daisy Manish Shah, V. S. Prasadarao Lingam, Neelima Khairatkar-Joshi, Indranil Mukhopadhyay
Publikováno v:
Pharmaceutical patent analyst. 4(3)
The transient receptor potential canonical (TRPC) channels have gained interest as potential therapeutic targets for respiratory diseases, neurological disorders, cardiovascular disorders, pain, cancer and several other pathological conditions. The T