Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Daisy Lam"'
Autor:
Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett
Publikováno v:
eLife, Vol 12 (2023)
Resolving fundamental molecular and functional processes underlying human synaptic development is crucial for understanding normal brain function as well as dysfunction in disease. Based upon increasing evidence of species-divergent features of brain
Externí odkaz:
https://doaj.org/article/1b1cfc36dbc340f8813d1636391740e6
Autor:
Darren M. C. Poon, Daisy Lam, Kenneth C. W. Wong, Cheuk-Man Chu, Michael Cheung, Frankie Mo, Joyce Suen, Chi-Fai Ng, Anthony T. C. Chan
Publikováno v:
Current Oncology, Vol 29, Iss 1, Pp 27-37 (2021)
Background: Stereotactic body radiotherapy (SBRT) has potential radiobiologic and economic advantages over conventional fractionated radiotherapy (CFRT) in localized prostate cancer (PC). This study aimed to compare the effects of these two distinct
Externí odkaz:
https://doaj.org/article/6689fd78bb3846d0977c867fc9c43239
Autor:
Darren M.C. Poon, Kuen Chan, Siu H. Lee, Tim W. Chan, Henry Sze, Eric K.C. Lee, Daisy Lam, Michelle F.T. Chan
Publikováno v:
Prostate International, Vol 6, Iss 1, Pp 24-30 (2018)
Background: This study aimed to compare the efficacy of abiraterone acetate (AA) versus docetaxel (T) as first-line treatment in chemo-naïve metastatic castration-resistant prostate cancer (mCRPC) patients with or without the ineligible factors of t
Externí odkaz:
https://doaj.org/article/edf841c8b6844c12b76d3bd3b64b9b71
Autor:
Dane Z. Hazelbaker, Amanda Beccard, Anne M. Bara, Nicole Dabkowski, Angelica Messana, Patrizia Mazzucato, Daisy Lam, Danielle Manning, Kevin Eggan, Lindy E. Barrett
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1315-1327 (2017)
Scaling of CRISPR-Cas9 technology in human pluripotent stem cells (hPSCs) represents an important step for modeling complex disease and developing drug screens in human cells. However, variables affecting the scaling efficiency of gene editing in hPS
Externí odkaz:
https://doaj.org/article/f8ca353ae99841db9505bd59d3848669
Autor:
Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008f9d606fa95833af908250dbc7cb32
https://doi.org/10.7554/elife.80168.sa2
https://doi.org/10.7554/elife.80168.sa2
Autor:
Sandy SK Ho, Sophie SF Hon, Esther Hung, Janet FY Lee, Frankie Mo, Macy Tong, Cathy So, Simon Chu, Dennis CK Ng, Daisy Lam, Carmen Cho, Tony WC Mak, Simon SM Ng, Kaori Futaba, Joyce Suen, KF To, Anthony WH Chan, William WK Yeung, Brigette BY Ma
Publikováno v:
Hong Kong medical journal = Xianggang yi xue za zhi. 28(3)
Neoadjuvant chemoradiotherapy is a standard treatment for locally advanced rectal cancer, for which pathological complete response is typically used as a surrogate survival endpoint. Neoadjuvant rectal score is a new biomarker that has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328634480b889bb4f46ba28928ee8109
https://pubmed.ncbi.nlm.nih.gov/35667869
https://pubmed.ncbi.nlm.nih.gov/35667869
Autor:
Alexander Liquori, Ian Slaymaker, Daisy Lam, Giuseppe Ciaramella, Dieter Lam, Adam J. Hartigan, David A. Born, Jeremy Decker, Fei Ann Ran, S. Haihua Chu, Lo-I Cheng, Holly A. Rees, Jeffrey Marshall, Michael S. Packer, Bob Gantzer, Nicole M. Gaudelli, Jenny Olins, Luis A. Barrera, Yi Yu
Publikováno v:
The CRISPR Journal. 4:169-177
Base editors are fusions of a deaminase and CRISPR-Cas ribonucleoprotein that allow programmable installment of transition mutations without double-strand DNA break intermediates. The breadth of potential base editing targets is frequently limited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a2df0d40b5dcfb8fde74d08414d7f2
https://doi.org/10.1089/crispr.2020.0144
https://doi.org/10.1089/crispr.2020.0144
Autor:
Martin H. Berryer, Gizem Rizki, Sara G. Susco, Daisy Lam, Angelica Messana, Darina Trendafilova, Anna Nathanson, Kyle W. Karhohs, Beth A. Cimini, Kathleen Pfaff, Anne E. Carpenter, Lee L. Rubin, Lindy E. Barrett
Resolving fundamental molecular and functional processes underlying human synaptic development is crucial for understanding normal brain function as well as dysfunction in disease. Based upon increasing evidence of species divergent features of brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a2378a0e9ee63b9ba7faa201e3b84e
https://doi.org/10.1101/2022.05.17.492322
https://doi.org/10.1101/2022.05.17.492322
Autor:
Sara G. Susco, Sulagna Ghosh, Patrizia Mazzucato, Gabriella Angelini, Amanda Beccard, Victor Barrera, Martin H. Berryer, Angelica Messana, Daisy Lam, Dane Z. Hazelbaker, Lindy E. Barrett
Publikováno v:
Cell reports. 40(10)
Down syndrome (DS), driven by an extra copy of chromosome 21 (HSA21), and fragile X syndrome (FXS), driven by loss of the RNA-binding protein FMRP, are two common genetic causes of intellectual disability and autism. Based upon the number of DS-impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af20a2fab4b2e2a86d2c4d1296c9c414
https://pubmed.ncbi.nlm.nih.gov/36070702
https://pubmed.ncbi.nlm.nih.gov/36070702
Autor:
Dane Z. Hazelbaker, Kevin Eggan, Daisy Lam, Lindy E. Barrett, Gabriella Angelini, Angelica Messana, Amanda Beccard, Patrizia Mazzucato
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
CRISPR-Cas9-mediated gene interference (CRISPRi) and activation (CRISPRa) approaches hold promise for functional gene studies and genome-wide screens in human pluripotent stem cells (hPSCs). However, in contrast to CRISPR-Cas9 nuclease approaches, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defdd3c777398d6464822a3fa31b5965
https://doi.org/10.1038/s41598-020-57500-1
https://doi.org/10.1038/s41598-020-57500-1