Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daisy D. Colón-López"'
Autor:
Emilee E. Colón-Lorenzo, Daisy D. Colón-López, Joel Vega-Rodríguez, Alice Dupin, David A. Fidock, Abel Baerga-Ortiz, José G. Ortiz, Jürgen Bosch, Adelfa E. Serrano
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Plasmodium falciparum parasites are increasingly drug-resistant, requiring the search for novel antimalarials with distinct modes of action. Enzymes in the glutathione pathway, including glutathione S-transferase (GST), show promise as novel antimala
Externí odkaz:
https://doaj.org/article/25976881602d408ca0f8df033ab758a2
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Cytotoxicity profiles of NSC305787 and the hits from MMV400 library on K12 and K7M2 mouse osteosarcoma cells as generated by xCELLigence RTCA during 48 hr incubation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04143dade111430c5aaf300c3e22ef72
https://doi.org/10.1158/1535-7163.22506195
https://doi.org/10.1158/1535-7163.22506195
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c859a020cb1806491369aaea5fd3e3
https://doi.org/10.1158/1535-7163.22506183
https://doi.org/10.1158/1535-7163.22506183
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Chemical structures of the small molecule inhibitor of ezrin, NSC305787, and quinoline-containing antimalarial agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11957f09142357dc01816be1cfd9a3f
https://doi.org/10.1158/1535-7163.22506204.v1
https://doi.org/10.1158/1535-7163.22506204.v1
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Representative images of embryos treated with NSC305787 and the hit compounds from MMV400 library are presented with different degrees of phenotypic abnormalities at later stages of embryonic development from 1 to 5 dpf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8885f8923f5ad2b6ce99d9db0fdcf8
https://doi.org/10.1158/1535-7163.22506189.v1
https://doi.org/10.1158/1535-7163.22506189.v1
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Representative steady-state affinity curve of primary hits from MMV400 library for binding to ezrin as measured by SPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be158ffe0f29057fd054cba647dd292
https://doi.org/10.1158/1535-7163.22506201
https://doi.org/10.1158/1535-7163.22506201
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Initial screening of primary hits for reduced cell motility phenotypes in zebrafish embryonic developmental assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147ab6aa6c4834b1ff50dc7b80c44774
https://doi.org/10.1158/1535-7163.22506180.v1
https://doi.org/10.1158/1535-7163.22506180.v1
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Effect of NSC305787 and the hits from MMV400 library on ezrin T567 phoshorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492a07fceade2aedf0fa44056475af5b
https://doi.org/10.1158/1535-7163.22506186
https://doi.org/10.1158/1535-7163.22506186
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Ezrin is a member of the ERM (ezrin, radixin, moesin) family of proteins and functions as a linker between the plasma membrane and the actin cytoskeleton. Ezrin is a key driver of tumor progression and metastatic spread of osteosarcoma. We discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143ab00b8e7cf2334caa67d928d228c6
https://doi.org/10.1158/1535-7163.c.6538317.v1
https://doi.org/10.1158/1535-7163.c.6538317.v1
Autor:
Aykut Üren, Jürgen Bosch, Jeffrey A. Toretsky, Eric Glasgow, Mikell Paige, Matthew Swift, Tsion Z. Minas, Yasemin Saygideger Kont, Jenny Han, Daisy D. Colón-López, Sung-Hyeok Hong, Haydar Çelik
Representative real time migration curves for K12 and K7M2 cells in response to vehicle (DMSO) or compound treatment as determined by electrical impedance expressed as cell index during 21 hr incubation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da61081ea162e35b84af0c7820e6a29b
https://doi.org/10.1158/1535-7163.22506192
https://doi.org/10.1158/1535-7163.22506192