Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daisuke Yoshidome"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Glutamate is an essential biological compound produced for various therapeutic and nutritional applications. The current glutamate production process requires a large amount of ammonium, which is generated through the energy-consuming and CO
Externí odkaz:
https://doaj.org/article/a6ba53176a8e49489e9cd355e37db320
Glutamate is an essential biological compound produced for various practical uses. However, the current glutamate production process requires a large amount of ammonium produced through the most energy-consuming and CO2-emitting Haber–Bosch process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ed40b85957d7c7316fc50429d3abfe
https://doi.org/10.21203/rs.3.rs-2844389/v1
https://doi.org/10.21203/rs.3.rs-2844389/v1
Autor:
Yoshiyuki Manabe, Masato Tsutsui, Kohtaro Hirao, Risako Kobayashi, Hiroshi Inaba, Kazunori Matsuura, Daisuke Yoshidome, Kazuya Kabayama, Koichi Fukase
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(61)
We have synthesized B-antigen-displaying dendrimers (16-mers) with different sizes and evaluated their affinity to their IgM antibody in order to investigate which design features lead to effective multivalency. Unexpectedly, the smallest dendrimer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86f6e7e18cb9a5b5a99d65d93abd4ba
https://pubmed.ncbi.nlm.nih.gov/35880726
https://pubmed.ncbi.nlm.nih.gov/35880726
Publikováno v:
ACS Catalysis. 8:3123-3128
We developed a palladium-catalyzed C–H transformation that enabled the synthesis of ketones from aldehydes and (hetero)aryl halides. The use of picolinamide ligands was key to achieving the transformation. Heteroaryl ketones, as well as diaryl keto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e64a60221c9fbdc96dd735a9c58604
https://doi.org/10.1021/acscatal.8b00440
https://doi.org/10.1021/acscatal.8b00440
Autor:
Daisuke Yoshidome, Yukari Fujimoto, Koichi Fukase, Shinsuke Inuki, Emi Kashiwabara, Zenyu Shiokawa
Publikováno v:
ChemMedChem. 11:2682-2689
Indoleamine 2,3-dioxygenase 1 (IDO1) has emerged as a key target for cancer therapy, as IDO1 plays a critical role in the capacity of tumor cells to evade the immune system. The pyrrolopiperazinone alkaloid longamide B and its derivatives were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21252a0b0ec7ba3b6b6de5559d8f996c
https://doi.org/10.1002/cmdc.201600446
https://doi.org/10.1002/cmdc.201600446
Autor:
Junichiro Kishi, Shinsuke Inuki, Natsumi Hirata, Yukari Fujimoto, Emi Kashiwabara, Daisuke Yoshidome, Osamu Ichihara
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(8)
Abstract CD1d is a non-polymorphic antigen-presenting glycoprotein that recognizes glycolipids as ligands. Ligands bind to the hydrophobic grooves of CD1d, and the resulting ligand-CD1d complexes activate natural killer T (NKT) cells by means of T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecb9f291a6d31f17d497d68523cec97
https://pubmed.ncbi.nlm.nih.gov/30824201
https://pubmed.ncbi.nlm.nih.gov/30824201
Autor:
Koichi Fukase, Yukari Fujimoto, Osamu Ichihara, Natsumi Hirata, Shunsuke Kita, Shinsuke Inuki, Katsumi Maenaka, Daisuke Yoshidome, Toshihiko Aiba
Publikováno v:
ResearcherID
The CD1d protein is a nonpolymorphic MHC class I-like protein that controls the activation of natural killer T (NKT) cells through the presentation of self- and foreign-lipid ligands, glycolipids, or phospholipids, leading to the secretion of various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2cca81dd5c9ba125dc2957e557c0e1
https://doi.org/10.1021/acschembio.6b00674
https://doi.org/10.1021/acschembio.6b00674
Autor:
Hyunwook Kwak, Thomas J. L. Mustard, Tsuguo Morisato, Alexander Goldberg, Daisuke Yoshidome, Mathew D. Halls, Jacob Gavartin
Publikováno v:
Journal of the Korean Ceramic Society. 53:317-324
Continued miniaturization and increasingly exact requirements for thin film deposition in the semiconductor industry is driving the search for new effective, efficient, selective precursors and processes. The requirements of defect-free, conformal fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2dda1cf27863140c3f95f085e7b0df4
https://doi.org/10.4191/kcers.2016.53.3.317
https://doi.org/10.4191/kcers.2016.53.3.317
Autor:
Nozomu Nagashima, Akihisa Osakabe, Motomu Kanai, Daiki Kato, Yoshifumi Amamoto, Yasuhiro Arimura, Shigehiro A. Kawashima, Daisuke Yoshidome, Hiroki Suto, Yuki Aoi, Hitoshi Kurumizaka, Kenzo Yamatsugu
Publikováno v:
Journal of the American Chemical Society. 139(22)
Posttranslational modifications (PTMs) of histones play an important role in the complex regulatory mechanisms governing gene transcription, and their dysregulation can cause diseases such as cancer. The lack of methods for site-selectively modifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b367ae9a0f82265158a5f282d1895a0
https://pubmed.ncbi.nlm.nih.gov/28534629
https://pubmed.ncbi.nlm.nih.gov/28534629
Autor:
Shinji Takamatsu, Koichi Fukase, Eiji Miyoshi, Yohei Takakura, Yoshihiro Kamada, Daisuke Yoshidome, Satomi Kasahara, Yoshiyuki Manabe, Xiaoxiao Yang
Publikováno v:
Bioorganicmedicinal chemistry. 25(11)
We developed α1,6-fucosyltransferase (FUT8) inhibitors through a diversity-oriented synthesis. The coupling reaction between the fucose unit containing alkyne and the guanine unit containing sulfonyl azide under various conditions afforded a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a4624416330a098965dffa332b8a46
https://pubmed.ncbi.nlm.nih.gov/28284868
https://pubmed.ncbi.nlm.nih.gov/28284868