Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Daisuke Nishizaki"'
Autor:
Yu Fujiwara, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mary K. Nesline, Jeffrey M. Conroy, Paul DePietro, Sarabjot Pabla, Scott M. Lippman, Razelle Kurzrock
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109632- (2024)
Summary: Indoleamine 2,3-dioxygenase 1 (IDO1), which catabolizes tryptophan, is a potential target to unlock the immunosuppressive tumor microenvironment. Correlations between IDO1 and immune checkpoint inhibitor (ICI) efficacy remain unclear. Herein
Externí odkaz:
https://doaj.org/article/9df1b09acc8f49f69d386a55f32c1121
Autor:
Nithya Krishnamurthy, Daisuke Nishizaki, Scott M. Lippman, Hirotaka Miyashita, Mary K. Nesline, Sarabjot Pabla, Jeffrey M. Conroy, Paul DePietro, Shumei Kato, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: CTLA-4 impedes the immune system’s antitumor response. There are two Food and Drug Administration-approved anti-CTLA-4 agents – ipilimumab and tremelimumab – both used together with anti-PD-1/PD-L1 agents. Objective: To assess the p
Externí odkaz:
https://doaj.org/article/302a5bad7fa94428a127ac93ea60fd33
Autor:
Jungah Lim, Razelle Kurzrock, Daisuke Nishizaki, Hirotaka Miyashita, Jacob J. Adashek, Suzanna Lee, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Scott M. Lippman, Shumei Kato
Publikováno v:
Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Background T‐cell immunoglobulin and mucin domain‐containing protein 3 (TIM‐3), an immune checkpoint receptor, dampens immune function. TIM‐3 antagonists have entered the clinic. Methods We analyzed TIM‐3 transcriptomic expression
Externí odkaz:
https://doaj.org/article/faba3e63388e469f81fc01e32dc0a947
Autor:
Jacob J. Adashek, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Pradip De, Suzanna Lee, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Scott Lippman, Razelle Kurzrock
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13155-13166 (2023)
Abstract Background Lymphocyte activation gene 3 (LAG‐3) or CD223 is a transmembrane protein that serves as an immune checkpoint which attenuates T‐cell activation. Many clinical trials of LAG‐3 inhibitors have had modest effects, but recent da
Externí odkaz:
https://doaj.org/article/cfe72fc33e194e9395740e5950d4b95c
Autor:
Aditya Shreenivas, Daisuke Nishizaki, Suzanna Lee, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Shumei Kato, Razelle Kurzrock
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4742 (2024)
ADORA2A (adenosine A2a receptor) and ADORA2B propagate immunoregulatory signals, including restricting both innate and adaptive immunity, though recent data also suggest a tumor suppressor effect in certain settings. We evaluated the RNA expression f
Externí odkaz:
https://doaj.org/article/d26f166fe9ee486db3018a55976a13a9
Autor:
Razelle Kurzrock, Sarabjot Pabla, Shumei Kato, Nithya Krishnamurthy, Paul DePietro, Mary K Nesline, Jeffrey M Conroy, Daisuke Nishizaki, Scott M Lippman, Hirotaka Miyashita
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/8be7f0786b434fde8b030d0afedc722a
Autor:
Daisuke Nishizaki, Nobuaki Hoshino, Koya Hida, Yoshitaka Nishikawa, Takahiro Horimatsu, Sachiko Minamiguchi, Katsuyuki Sakanaka, Yoshiharu Sakai
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 4, Iss 4, Pp 174-180 (2020)
Objective: Additional surgery is considered for patients at high risk for lymph node metastasis (LNM) after local resection for early rectal cancer. Several factors are considered as indications for additional surgery, although there are currently no
Externí odkaz:
https://doaj.org/article/18738a4d9209411ca2d0f0f282547d53
Autor:
Takuya Takami, Yoshiro Itatani, Rintaro Shibuya, Yoshiyuki Kiyasu, Keiko Kasahara, Daisuke Nishizaki, Ryosuke Okamura, Tomoaki Okada, Tatsuto Nishigori, Nobuaki Hoshino, Shigeo Hisamori, Shigeru Tsunoda, Koya Hida, Kenji Kawada, Kazutaka Obama
Publikováno v:
Asian Journal of Endoscopic Surgery. 16:86-89
Autor:
Daisuke Nishizaki, Yusuke Fujita, Takashi Sakamoto, Akihiro Ueda, Hiroto Kawakami, Masahiro Yamada, Kae Okoshi, Koya Hida, Kazutaka Obama
Publikováno v:
Supportive Care in Cancer. 31
Autor:
Jacob J. Adashek, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Pradip De, Suzanna Lee, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Scott Lippman, Razelle Kurzrock
Publikováno v:
Cancer Medicine.