Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Daisuke Matsumaru"'
Autor:
Tetsuya Oishi, Daisuke Matsumaru, Nao Ota, Hiroshi Kitamura, Tianxiang Zhang, Yohei Honkura, Yukio Katori, Hozumi Motohashi
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 6, Iss 1, Pp 1-15 (2020)
Abstract Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pa
Externí odkaz:
https://doaj.org/article/90942eff5eaa478aa91b20376ff615a1
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers
Autor:
Keito Okazaki, Hayato Anzawa, Zun Liu, Nao Ota, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Takuma Suzuki, Fumiki Katsuoka, Shu Tadaka, Ikuko Motoike, Mika Watanabe, Kazuki Hayasaka, Akira Sakurada, Yoshinori Okada, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Aberrant activation of NRF2 in cancer cells contributes to tumorigenicity and therapeutic resistance. Here, the authors show that NRF2 cooperates with CEBPB and remodels enhancers to confer tumor-initiating activity on NRF2- activated non-small cell
Externí odkaz:
https://doaj.org/article/e2fd0ce97bcb4b3aabb6a909e9e673dd
Autor:
Takahiro Onoki, Yoshihiro Izumi, Masatomo Takahashi, Shohei Murakami, Daisuke Matsumaru, Nao Ohta, Sisca Meida Wati, Nozomi Hatanaka, Fumiki Katsuoka, Mitsuharu Okutsu, Yutaka Yabe, Yoshihiro Hagiwara, Makoto Kanzaki, Takeshi Bamba, Eiji Itoi, Hozumi Motohashi
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101966- (2021)
Skeletal muscle health is important for the prevention of various age-related diseases. The loss of skeletal muscle mass, which is known as sarcopenia, underlies physical disability, poor quality of life and chronic diseases in elderly people. The tr
Externí odkaz:
https://doaj.org/article/b1814c52341d47f589155d4a01d72b57
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101603- (2020)
Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva. In particular, unstimulated basal salivary flow decreases with ag
Externí odkaz:
https://doaj.org/article/2a11545f42cd4c038bb5db966d93b3f3
Autor:
Daisuke Matsumaru, Hozumi Motohashi
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1929 (2021)
Aging is inevitable, but the inherently and genetically programmed aging process is markedly influenced by environmental factors. All organisms are constantly exposed to various stresses, either exogenous or endogenous, throughout their lives, and th
Externí odkaz:
https://doaj.org/article/6e2083b5450e48b8a7a889c08df79958
Autor:
Keito Okazaki, Hayato Anzawa, Zun Liu, Nao Ota, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Takuma Suzuki, Fumiki Katsuoka, Shu Tadaka, Ikuko Motoike, Mika Watanabe, Kazuki Hayasaka, Akira Sakurada, Yoshinori Okada, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-20927-9.
Externí odkaz:
https://doaj.org/article/139e41cc1a864ed2a000c137c48e2d9e
Autor:
Shigeru Makino, Olena Zhulyn, Rong Mo, Vijitha Puviindran, Xiaoyun Zhang, Takuya Murata, Ryutaro Fukumura, Yuichi Ishitsuka, Hayato Kotaki, Daisuke Matsumaru, Shunsuke Ishii, Chi-Chung Hui, Yoichi Gondo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119455 (2015)
Hedgehog signaling is primarily transduced by two transcription factors: Gli2, which mainly acts as a full-length activator, and Gli3, which tends to be proteolytically processed from a full-length form (Gli3FL) to an N-terminal repressor (Gli3REP).
Externí odkaz:
https://doaj.org/article/5366ddfafc8c445db67a20a837d067f6
Autor:
Ryuma Haraguchi, Daisuke Matsumaru, Naomi Nakagata, Shinichi Miyagawa, Kentaro Suzuki, Sohei Kitazawa, Gen Yamada
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42245 (2012)
Congenital diseases of the urinary tract are frequently observed in infants. Such diseases present a number of developmental anomalies such as hydroureter and hydronephrosis. Although some genetically-modified mouse models of growth factor signaling
Externí odkaz:
https://doaj.org/article/c35f56cb0e704907a6b0e05f2cb08553
Autor:
Daisuke Matsumaru, Ryuma Haraguchi, Shinichi Miyagawa, Jun Motoyama, Naomi Nakagata, Frits Meijlink, Gen Yamada
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16260 (2011)
An omphalocele is one of the major ventral body wall malformations and is characterized by abnormally herniated viscera from the body trunk. It has been frequently found to be associated with other structural malformations, such as genitourinary malf
Externí odkaz:
https://doaj.org/article/ba1541f9af4542b29a51dbbcc0ce5aad
Publikováno v:
Development, Growth & Differentiation. 65:132-140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85eb6bb1df7088cd68cef12dccb95097
https://doi.org/10.1111/dgd.12840
https://doi.org/10.1111/dgd.12840