Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Daisuke Koga"'
Autor:
Kosuke Kamemura, Rio Kozono, Mizuki Tando, Misako Okumura, Daisuke Koga, Satoshi Kusumi, Kanako Tamai, Aoi Okumura, Sayaka Sekine, Daichi Kamiyama, Takahiro Chihara
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract VAMP-associated protein (VAP) is a type IV integral transmembrane protein at the endoplasmic reticulum (ER). Mutations in human VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS). The N-terminal major sperm protein (MSP) domai
Externí odkaz:
https://doaj.org/article/69ec5106dc09488eac67f4e326fe7e62
Autor:
Shintaro Funasaki, Atsushi Hatano, Hirokazu Nakatsumi, Daisuke Koga, Osamu Sugahara, Kanae Yumimoto, Masaya Baba, Masaki Matsumoto, Keiichi I. Nakayama
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107552- (2023)
Summary: Developing CD4+CD8+ double-positive (DP) thymocytes with randomly generated T cell receptors (TCRs) undergo positive (maturation) or negative (apoptosis) selection on the basis of the strength of TCR stimulation. Selection fate is determined
Externí odkaz:
https://doaj.org/article/55f528e54c80473192fe5df1266a866c
Autor:
Asami Okada, Misuzu Yamada‐Yamashita, Yukari Tominaga, Kyoka Jo, Hiroyasu Mori, Reiko Suzuki, Masashi Ishizu, Motoyuki Tamaki, Yuko Akehi, Yuichi Takashi, Daisuke Koga, Eisuke Shimokita, Fuminori Tanihara, Kiyoe Kurahashi, Sumiko Yoshida, Yukari Mitsui, Shiho Masuda, Itsuro Endo, Ken‐ichi Aihara, Shoji Kagami, Masahiro Abe, Kevin Ferreri, Yoshio Fujitani, Munehide Matsuhisa, Akio Kuroda
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 7, Pp 1140-1148 (2022)
Abstract Aims/Introduction Several research groups have reported methods for quantifying pancreatic beta cell (β‐cell) injury by measuring β‐cell‐specific CpG unmethylation of the insulin gene in circulation using digital droplet PCR or next
Externí odkaz:
https://doaj.org/article/885cf638d27f4b7d8643cfc191e2e4cf
Autor:
Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen, Sylvie Robine, Makoto M. Taketo, Toshiro Sato, Keiichi I. Nakayama
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Rapid turnover and regeneration of intestinal epithelium requires distinct intestinal stem cell (ISC) populations. Here the authors show p57 marks quiescent ISCs, and that differentiated cells revert to stem cell state after injury, through dynamic r
Externí odkaz:
https://doaj.org/article/016b3ef4cf6d4e8f94825f680194ae25
Autor:
Takahiro Sato, Kanae Oishi, Daisuke Koga, Takanori Ida, Yusuke Sakai, Kenji Kangawa, Masayasu Kojima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Ghrelin, a circulating orexigenic hormone secreted from the stomach, stimulates appetite and food intake by activating the hypothalamic arcuate nucleus. Administration of exogenous ghrelin exerts anabolic effects, causing weight gain, increa
Externí odkaz:
https://doaj.org/article/3760edb0716a4432af266d328de19dbe
Autor:
Naoshi Hotta, Takahiro Tadokoro, John Henry, Daisuke Koga, Keisuke Kawata, Hiroyuki Ishida, Yuko Oguma, Akihiro Hirata, Masato Mitsuhashi, Kenji Yoshitani
Publikováno v:
Biomarker Insights, Vol 17 (2022)
Background: Extracellular vesicles (EV) released from neurons into the blood can reflect the state of nervous tissue. Measurement of neuron derived EV (NDE) may serve as an indicator of brain injury. Methods: A sandwich immunoassay was established to
Externí odkaz:
https://doaj.org/article/39559717d92b4efeb4a626cfeb7bc7c1
Autor:
Naohiro Wakabayashi, Takumi Yoshida, Kyohei Oyama, Daisuke Naruse, Masahiro Tsutsui, Yuta Kikuchi, Daisuke Koga, Hiroyuki Kamiya
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The low patency of synthetic vascular grafts hinders their practical applicability. Polyvinyl alcohol (PVA) is a non-toxic, highly hydrophilic polymer; thus, we created a PVA-coated polycaprolactone (PCL) nanofiber vascular graft (PVA–PCL graft). I
Externí odkaz:
https://doaj.org/article/5e6366bd45574e5d987d5ac8b1654926
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Scanning electron microscopy (SEM) has contributed to elucidating the ultrastructure of bio-specimens in three dimensions. SEM imagery detects several kinds of signals, of which secondary electrons (SEs) and backscattered electrons (BSEs) are the mai
Externí odkaz:
https://doaj.org/article/9b1861472feb4e70beb27ea3eae1cf22
Autor:
Chisato Hoshino, Daisuke Koga, Gaku Koyano, Yuki Yamauchi, Tomoko Sakai, Atsushi Okawa, Tetsuya Jinno
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217068 (2019)
Nerve palsy following total hip arthroplasty (THA) can have a serious effect on a patient`s functional prognosis and on cost-effectiveness, and it is the leading cause of THA-associated medical litigation. However, only a few studies focus on femoral
Externí odkaz:
https://doaj.org/article/542506abaf2e466cb34bb1abc8e93ebf
Autor:
Kozo Nagai, Yukari Suyama, Daisuke Koga, Masanori Nishi, Chiaki Iida, Katsuya Tashiro, Atsushi Danjo, Keita Kai, Muneaki Matsuo
Publikováno v:
Case Reports in Oncology, Vol 9, Iss 2, Pp 440-446 (2016)
We described an 11-year-old boy suffering from pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with heart metastasis at diagnosis and arterial tumor embolisms during chemotherapy. Both the heart metastasis and pericardial
Externí odkaz:
https://doaj.org/article/5226fb21aedd4016b3540eaacbdf40ea