Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Daisuke Kawaba"'
1
Akademický článek
Cleaved Form of Osteopontin in Urine as a Clinical Marker of Lupus Nephritis.
Autor: Koji Kitagori, Hajime Yoshifuji, Takuma Oku, Chiyomi Sasaki, Hitomi Miyata, Keita P Mori, Toshiki Nakajima, Koichiro Ohmura, Daisuke Kawabata, Naoichiro Yukawa, Yoshitaka Imura, Kosaku Murakami, Ran Nakashima, Takashi Usui, Takao Fujii, Kaoru Sakai, Motoko Yanagita, Yoshitaka Hirayama, Tsuneyo Mimori
Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167141 (2016)
We assessed the utility of two forms of osteopontin (OPN), OPN full and its cleaved form (OPN N-half), in plasma and urine as markers of disease activity in lupus nephritis (LN). Samples were collected from patients with systemic lupus erythematosus
Externí odkaz: https://doaj.org/article/43bb310ce9454fd8b32286dcc2edc487
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3
Akademický článek
Three groups in the 28 joints for rheumatoid arthritis synovitis--analysis using more than 17,000 assessments in the KURAMA database.
Autor: Chikashi Terao, Motomu Hashimoto, Keiichi Yamamoto, Kosaku Murakami, Koichiro Ohmura, Ran Nakashima, Noriyuki Yamakawa, Hajime Yoshifuji, Naoichiro Yukawa, Daisuke Kawabata, Takashi Usui, Hiroyuki Yoshitomi, Moritoshi Furu, Ryo Yamada, Fumihiko Matsuda, Hiromu Ito, Takao Fujii, Tsuneyo Mimori
Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59341 (2013)
Rheumatoid arthritis (RA) is a joint-destructive autoimmune disease. Three composite indices evaluating the same 28 joints are commonly used for the evaluation of RA activity. However, the relationship between, and the frequency of, the joint involve
Externí odkaz: https://doaj.org/article/9198ec5ae8a746a5a59f84d6c76f05ea
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4
Akademický článek
Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.
Autor: Masaki Katayama, Koichiro Ohmura, Naoichiro Yukawa, Chikashi Terao, Motomu Hashimoto, Hajime Yoshifuji, Daisuke Kawabata, Takao Fujii, Yoichiro Iwakura, Tsuneyo Mimori
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e62231 (2013)
OBJECTIVE: Th17 has been shown to have a pivotal role in the development of arthritis. However, the role of IL-17 in the T cell-independent effector phase has not fully been examined. We investigated whether IL-17 is involved in the effector phase of
Externí odkaz: https://doaj.org/article/35fde644ce85449aaa9cbe09c8ce32d2
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5
Akademický článek
Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals.
Autor: Mikiko Iguchi-Hashimoto, Takashi Usui, Hajime Yoshifuji, Masakazu Shimizu, Shio Kobayashi, Yoshinaga Ito, Kosaku Murakami, Aoi Shiomi, Naoichiro Yukawa, Daisuke Kawabata, Takaki Nojima, Koichiro Ohmura, Takao Fujii, Tsuneyo Mimori
Publikováno v: PLoS ONE, Vol 6, Iss 10, p e27020 (2011)
Calpain, a calcium-dependent cysteine protease, is reportedly involved in the pathophysiology of autoimmune diseases such as rheumatoid arthritis (RA). In addition, autoantibodies against calpastatin, a natural and specific inhibitor of calpain, are
Externí odkaz: https://doaj.org/article/fc568a9b5fea4f299c5dba66942677f7
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6
Akademický článek
Enhanced selection of high affinity DNA-reactive B cells following cyclophosphamide treatment in mice.
Autor: Daisuke Kawabata, Jeganathan Venkatesh, Meera Ramanujam, Anne Davidson, Christine M Grimaldi, Betty Diamond
Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8418 (2010)
A major goal for the treatment of patients with systemic lupus erythematosus with cytotoxic therapies is the induction of long-term remission. There is, however, a paucity of information concerning the effects of these therapies on the reconstituting
Externí odkaz: https://doaj.org/article/58da7bd4436b44b5a446b14125210b1d
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