Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daisuke Ikawa"'
Autor:
Yasunari Yamaguchi, Kazuya Okamura, Kazuhiko Yamamuro, Kazuki Okumura, Takashi Komori, Michihiro Toritsuka, Ryohei Takada, Yosuke Nishihata, Daisuke Ikawa, Takahira Yamauchi, Manabu Makinodan, Hiroki Yoshino, Yasuhiko Saito, Hideo Matsuzaki, Toshifumi Kishimoto, Sohei Kimoto
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundSocial isolation during critical periods of development is associated with alterations in behavior and neuronal circuitry. This study aimed to investigate the immediate and developmental effects of social isolation on firing properties, neu
Externí odkaz:
https://doaj.org/article/2399da121464402f9f2969039e6207fe
Autor:
Manabu Makinodan, Daisuke Ikawa, Kazuhiko Yamamuro, Yasunori Yamashita, Michihiro Toritsuka, Sohei Kimoto, Takahira Yamauchi, Kazuki Okumura, Takashi Komori, Shin-ichi Fukami, Hiroki Yoshino, Shigenobu Kanba, Akio Wanaka, Toshifumi Kishimoto
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Social isolation is an important factor in the development of psychiatric disorders. It is necessary to develop an effective psychological treatment, such as cognitive rehabilitation, for children who have already suffered from social isolat
Externí odkaz:
https://doaj.org/article/c39060ba5fae40cba5473af9a2eb09b9
Autor:
Yasunori Yamashita, Manabu Makinodan, Michihiro Toritsuka, Takahira Yamauchi, Daisuke Ikawa, Sohei Kimoto, Takashi Komori, Ryohei Takada, Yoshinori Kayashima, Kaori Hamano-Iwasa, Masatsugu Tsujii, Hideo Matsuzaki, Toshifumi Kishimoto
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
The gut hormone ghrelin has been implicated in a variety of functional roles in the central nervous system through the brain-gut axis, one of which is an anti-inflammatory effect. An aberrant brain-gut axis producing immune dysfunction has been impli
Externí odkaz:
https://doaj.org/article/d288a3c1d56c4636aaef041d6704bc8e
Autor:
Manabu Makinodan, Kazuki Okumura, Daisuke Ikawa, Yasunori Yamashita, Kazuhiko Yamamuro, Michihiro Toritsuka, Sohei Kimoto, Takahira Yamauchi, Takashi Komori, Yoshinori Kayashima, Hiroki Yoshino, Akio Wanaka, Toshifumi Kishimoto
Publikováno v:
Heliyon, Vol 3, Iss 11, Pp e00468- (2017)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction, poor communication skills, and repetitive/restrictive behaviors. Recent studies have indicated that early rehabilitative intervention can al
Externí odkaz:
https://doaj.org/article/d4131f4f7f77488887906761e88a93dd
Autor:
Kuniaki Kiuchi, Soichiro Kitamura, Toshiaki Taoka, Fumihiko Yasuno, Masami Tanimura, Kiwamu Matsuoka, Daisuke Ikawa, Michihiro Toritsuka, Kazumichi Hashimoto, Manabu Makinodan, Jun Kosaka, Masayuki Morikawa, Kimihiko Kichikawa, Toshifumi Kishimoto
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104007 (2014)
Subjective cognitive impairment may be a very early at-risk period of the continuum of dementia. However, it is difficult to discriminate at-risk states from normal aging. Thus, detection of the early pathological changes in the subjective cognitive
Externí odkaz:
https://doaj.org/article/5bf415b12ab34c9e87c2acbfa3dea683
Autor:
Manabu Makinodan, Aya Okuda-Yamamoto, Daisuke Ikawa, Michihiro Toritsuka, Tomohiko Takeda, Sohei Kimoto, Kouko Tatsumi, Hiroaki Okuda, Yu Nakamura, Akio Wanaka, Toshifumi Kishimoto
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66124 (2013)
Demyelination is generally regarded as a consequence of oligodendrocytic cell death. Oligodendrocyte processes that form myelin sheaths may, however, degenerate and regenerate independently of the cell body, in which case cell death does not necessar
Externí odkaz:
https://doaj.org/article/04b2c59c936b4fd1b5c5595f30b349bf
Autor:
Shohei Tanaka, Toyosaku Ota, Toshifumi Kishimoto, Sohei Kimoto, Michihiro Toritsuka, Manabu Makinodan, Junzo Iida, Yasunori Yamashita, Kazuhiko Yamamuro, Hiroki Yoshino, Naoko Kishimoto, Daisuke Ikawa
Publikováno v:
Journal of Affective Disorders. 234:45-53
Background Schizophrenia (SZ) and bipolar disorder (BD) are characterized by different clinical symptoms, and have previously been considered as categorically separate. However, several lines of evidence controversially suggest that these two disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19928843ec3549d926f89d7b72ef3937
https://doi.org/10.1016/j.jad.2018.02.065
https://doi.org/10.1016/j.jad.2018.02.065
Autor:
Sohei Kimoto, Manabu Makinodan, Kaori Hamano-Iwasa, Daisuke Ikawa, Hideo Matsuzaki, Michihiro Toritsuka, Takashi Komori, Yasunori Yamashita, Takahira Yamauchi, Toshifumi Kishimoto
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 54:523-527
Lymphoblastoid cell lines (LCLs) are nearly immortalized B lymphocytes that are used as long-lasting supply of human cells for studies on gene expression analyses. However, studies on the stability of the cellular features of LCLs are scarce. To addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a313abbd50604435a51b045958f87b6c
https://doi.org/10.1007/s11626-018-0267-1
https://doi.org/10.1007/s11626-018-0267-1
Autor:
Takuya Matsumoto, Kazumichi Hashimoto, Wado Akamatsu, Yasuhiko Saito, Daisuke Ikawa, Shin ichi Fukami, Kyosuke Watanabe, Yohei Okada, Manabu Makinodan, Chieko Aoki, Ryohei Takada, Yoichi Ogawa, Michihiro Toritsuka, Hideyuki Okano, Kazuhiko Yamamuro, Sohei Kimoto, Hiroki Yoshino, Kazuya Okamura, Toshifumi Kishimoto, Kaori Hamano-Iwasa
Publikováno v:
Neurochemistry International. 150:105179
Schizophrenia is a major psychiatric disorder, but the molecular mechanisms leading to its initiation or progression remain unclear. To elucidate the pathophysiology of schizophrenia, we used an in vitro neuronal cell culture model involving human in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf74332dece541609414399bfd1883c
https://doi.org/10.1016/j.neuint.2021.105179
https://doi.org/10.1016/j.neuint.2021.105179
Autor:
Ryohei Takada, Takashi Komori, Yasunori Yamashita, Yoshinori Kayashima, Takahira Yamauchi, Toshifumi Kishimoto, Kaori Hamano-Iwasa, Hideo Matsuzaki, Manabu Makinodan, Masatsugu Tsujii, Sohei Kimoto, Daisuke Ikawa, Michihiro Toritsuka
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 10 (2019)
Frontiers in Psychiatry, Vol 10 (2019)
The gut hormone ghrelin has been implicated in a variety of functional roles in the central nervous system through the brain-gut axis, one of which is an anti-inflammatory effect. An aberrant brain-gut axis producing immune dysfunction has been impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593c59e6a50f7c4c2d9d62f72578aded
https://doi.org/10.3389/fpsyt.2019.00152
https://doi.org/10.3389/fpsyt.2019.00152