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pro vyhledávání: '"Daisuke Higashiyama"'
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 82:224-231
BACKGROUND: In humans, fetal ethanol exposure can cause holoprosencephaly (HPE), one of the most common birth defects that is characterized by brain, facial, and oral abnormalities. However, the pathogenesis of HPE is not clear. In the present study,
Autor:
Daisuke Higashiyama, Makoto Ishibashi, Munekazu Komada, Toshiya Takigawa, Kohei Shiota, Hirotomo Saitsu
Publikováno v:
Birth defects research. Part A, Clinical and molecular teratology. 79(7)
BACKGROUND: Prenatal exposure to ethanol induces holoprosencephalic malformations in both humans and laboratory animals. However, its teratogenic window for inducing holoprosencephaly is narrow, and the teratogenic mechanism is not well understood. I