Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Daisuke Fujioka"'
Autor:
Makoto Murakami, Takamitsu Nakamura, Keiji Miyazawa, Yosuke Watanabe, Kiyotaka Kugiyama, Takashi Yokoyama, Daisuke Fujioka
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 29:692-718
Aims It was suggested that group V secretory phospholipase A2 (sPLA2-V) existed in the nucleus. This study examined whether nuclear sPLA2-V plays a role in endocytosis of acetylated low-density lipoprotein (AcLDL) in monocyte/macrophage-like cell lin
Autor:
Kiyotaka Kugiyama, Ken-ichi Kawabata, Manabu Uematsu, Juntaro Deyama, Jun-ei Obata, Yosuke Watanabe, Takamitsu Nakamura, Daisuke Fujioka, Yukio Saito, Toru Yoshizaki, Kazuto Nakamura, Tsuyoshi Kobayashi
Publikováno v:
Journal of Cardiac Failure. 26:733-738
Background Although animal studies showed that Follistatin-like 1 (FSTL1) exerts cardioprotective effects against ischemic injury, little is known in humans. We examined whether FSTL1 is secreted in an infarcted myocardium and whether its production
Autor:
Hiroki Kishi, Kazuyuki Yamaguchi, Kazuto Nakamura, Kazuhiro Watanabe, Kiyotaka Kugiyama, Daisuke Fujioka
Publikováno v:
Inflammation. 43:1097-1109
Secretory phospholipase A2 (sPLA2) plays a critical role in the pathogenesis of various inflammatory diseases through production of pro-inflammatory eicosanoids. PLA2 receptor 1 (PLA2R) acts as a clearance receptor for sPLA2s. This study examined whe
Autor:
Yosuke Watanabe, Yukio Saito, Kiyotaka Kugiyama, Manabu Uematsu, Daichi Inomata, Tsuyoshi Kobayashi, Takeo Horikoshi, Takamitsu Nakamura, Toru Yoshizaki, Daisuke Fujioka, Kazuto Nakamura
Publikováno v:
Free radical biologymedicine. 176
Reactive oxygen species that increase during cardiovascular disease (CVD) react with protein cysteine residues to form a glutathione adduct by S-glutathionylation, which is selectively removed by glutaredoxin-1 (Glrx). We previously showed that S-glu
Autor:
Kazuhiro Watanabe, Kiyotaka Kugiyama, Jun-ei Obata, Takamitsu Nakamura, Yosuke Watanabe, Yuki Fujihara, Daisuke Fujioka, Takeo Horikoshi
Publikováno v:
Circulation Journal. 83:1302-1308
BACKGROUND This study examined the predictive value of remnant lipoprotein levels for cardiovascular events (CVEs) in patients with stable coronary artery disease (CAD) and low-density lipoprotein cholesterol (LDL-C) levels
Autor:
Ken-ichi Kawabata, Juntaro Deyama, Takamitsu Nakamura, Yosuke Watanabe, Jun-ei Obata, Yukio Saito, Manabu Uematsu, Kazuhiro Watanabe, Kiyotaka Kugiyama, Toru Yoshizaki, Daisuke Fujioka, Tsuyoshi Kobayashi, Kazuto Nakamura
Publikováno v:
Clinical and Experimental Nephrology. 23:920-927
Stromal cell-derived factor-1α (SDF-1α) is an inflammatory chemokine that plays a critical role in cardiovascular disease. Although persistent inflammation causes renal dysfunction, it remains unclear whether SDF-1α is related to progression of ch
Autor:
Daisuke, Fujioka, Yosuke, Watanabe, Takamitsu, Nakamura, Takashi, Yokoyama, Keiji, Miyazawa, Makoto, Murakami, Kiyotaka, Kugiyama
Publikováno v:
Journal of atherosclerosis and thrombosis. 29(5)
It was suggested that group V secretory phospholipase ARAW264.7 cells were transfected with shRNA vector targeting sPLAIn immunofluorescence microscopic studies, sPLANuclear sPLA
Autor:
Takamitsu Nakamura, Manabu Uematsu, Yosuke Watanabe, Yukio Saito, Kiyotaka Kugiyama, Jyun-ei Obata, Kazuto Nakamura, Toru Yoshizaki, Takeo Horikoshi, Tsuyoshi Kobayashi, Daisuke Fujioka
Publikováno v:
Journal of cardiology. 78(2)
Renal dysfunction, defined as a lower estimated glomerular filtration rate (eGFR), has been shown to be related to cardiovascular events in patients with myocardial infarction (MI). However, the contribution of renal tubulointerstitial damage to the
Autor:
Kazuto Nakamura, Yosuke Watanabe, Takamitsu Nakamura, Kazuhiro Watanabe, Kiyotaka Kugiyama, Kazunori Watanabe, Daisuke Fujioka, Jun-ei Obata
Publikováno v:
American Journal of Physiology-Cell Physiology. 315:C398-C408
Murine membrane-bound phospholipase A2receptor 1 (PLA2R) is shed and released into plasma in a soluble form that retains all of the extracellular domains. Relatively little is known about human PLA2R. This study examined whether human soluble PLA2R h
Autor:
Manabu Uematsu, Kazuhiro Watanabe, Kiyotaka Kugiyama, Takamitsu Nakamura, Toru Yoshizaki, Jun-ei Obata, Kazuto Nakamura, Daisuke Fujioka
Publikováno v:
Journal of Cardiology. 71:367-374
Although angiotensin II receptor blockers (ARBs) have been shown to have anti-inflammatory effects on infarcted myocardium in experimental models, little is known in humans. Stromal cell-derived factor-1α (SDF-1α), a pro-inflammatory chemokine, is