Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daisuke Aotani"'
Autor:
Akiko Hayakawa‐Iwamoto, Daisuke Aotani, Yuki Shimizu, Shota Kakoi, Chie Hasegawa, Shunsuke Itoh, Asami Fujii, Katsushi Takeda, Takashi Yagi, Hiroyuki Koyama, Kenro Imaeda, Kandai Nozu, China Nagano, Hiromi Kataoka, Tomohiro Tanaka
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 5, Pp 923-926 (2022)
Abstract A 34‐year‐old man visited our Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, because of dry mouth and weight loss. His plasma glucose level was 32.8 mmol/L and se
Externí odkaz:
https://doaj.org/article/33e19e6b176b49a09bb2846e6884f022
Autor:
Ryota Izumi, Toru Kusakabe, Michio Noguchi, Hiroshi Iwakura, Tomohiro Tanaka, Takashi Miyazawa, Daisuke Aotani, Kiminori Hosoda, Kenji Kangawa, Kazuwa Nakao
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1575-1585 (2018)
Angiopoietin-like protein (ANGPTL)8 is a liver- and adipocyte-derived protein that controls plasma triglyceride (TG) levels. Most animal studies have used mouse models. Here, we generated an Angptl8 KO rat model using a clustered regulatory interspac
Externí odkaz:
https://doaj.org/article/b764ac46e3b5465abbc3c35599446ab0
Autor:
Hidenari Nomura, Cheol Son, Daisuke Aotani, Yoshiyuki Shimizu, Goro Katsuura, Michio Noguchi, Toru Kusakabe, Tomohiro Tanaka, Takashi Miyazawa, Kiminori Hosoda, Kazuwa Nakao
Publikováno v:
Neuroscience Research. 177:94-102
While hypothalamic leptin resistance can occur prior to establishment of obesity, clarification is needed as to whether the impaired response to leptin in the reward-related nuclei occurs independently of obesity. To answer this question, we attempte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54974a8f22c9d9933405037a40ef343b
https://doi.org/10.1016/j.neures.2021.12.007
https://doi.org/10.1016/j.neures.2021.12.007
Autor:
Katsushi Takeda, Daisuke Aotani, Yusuke Kuga, Tomoki Jinno, Tingting Guo, Kento Ogawa, Yuki Shimizu, Rei Hattori, Takashi Yagi, Hiroyuki Koyama, Shigenobu Matsumura, Hiromi Kataoka, Tomohiro Tanaka
Publikováno v:
Biochemical and Biophysical Research Communications. 588:140-146
Smoking cessation increases body weight. The underlying mechanisms, however, have not been fully understood. We here report an establishment of a mouse model that exhibits an augmented body weight gain after nicotine withdrawal. High fat diet-fed mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea3761180039e8c3a8d559a73e5f51f
https://doi.org/10.1016/j.bbrc.2021.12.064
https://doi.org/10.1016/j.bbrc.2021.12.064
Autor:
Kento Ogawa, Hiroyuki Koyama, Daisuke Aotani, Kenro Imaeda, Hiromi Kataoka, Tomohiro Tanaka, Takashi Yagi, Hideomi Ohguchi, Katsushi Takeda, Tingting Guo
Publikováno v:
Biochemical and Biophysical Research Communications. 524:385-391
Pemafibrate, a selective peroxisome proliferator-activated receptor (PPAR) α modulator, is a new drug that specifically modulates PPARα conformation and co-activator recruitment, thereby lowers plasma triglycerides with less off-target effects. Cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb5662980a7871a3a17b4d641d94c46
https://doi.org/10.1016/j.bbrc.2020.01.118
https://doi.org/10.1016/j.bbrc.2020.01.118
Autor:
Mari Satoh, Ken Ebihara, Yoshihiro Ogawa, Megumi Aizawa-Abe, Daisuke Aotani, Tomohiro Tanaka, Tohru Yorifuji, Kazuwa Nakao, Toru Kusakabe
Publikováno v:
Endocrine journal. 68(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c6630221988fb612f3ff77f86aa21c
https://pubmed.ncbi.nlm.nih.gov/34373417
https://pubmed.ncbi.nlm.nih.gov/34373417
Autor:
Shinichi Shiona, Shoichiro Kanda, Shuichi Ito, Ryoko Harada, Satoshi Tazoe, Motoshi Hattori, Shinichiro Ohara, Shogo Minamikawa, Naoya Morisada, Kenji Ishikura, Tomohiko Yamamura, Yukiko Mori, Daisuke Aotani, Mayumi Enseki, Hiroyo Kourakata, Katsuaki Kasahara, Miki Washiyama, China Nagano, Kazumoto Iijima, Kandai Nozu, Nana Sakakibara, Yoshinori Araki, Koichi Kamei, Takeshi Yamada, Kenichiro Miura, Ryojiro Tanaka, Akane Seo, Chieko Matsumura, Keisuke Sugimoto
Publikováno v:
Clinical and Experimental Nephrology. 23(9):1119-1129
Background Hepatocyte nuclear factor 1β(HNF1B), located on chromosome 17q12, causes renal cysts and diabetes syndrome (RCAD). Moreover, various phenotypes related to congenital anomalies of the kidney and urinary tract (CAKUT) or Bartter-like electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1808fa9ad048ab66aa9d7a9b2658b6
https://hdl.handle.net/20.500.14094/90007295
https://hdl.handle.net/20.500.14094/90007295
Autor:
Yuki Shimizu, Shota Kakoi, Akiko Hayakawa, Chie Hasegawa, Tomohiro Tanaka, Hiroyuki Koyama, Satoshi Yasuda, Takashi Yagi, Tomoyuki Akiyama, Kenro Imaeda, Hiromi Kataoka, Yasuhisa Ohata, Keiichi Ozono, Daisuke Aotani
Publikováno v:
Internal Medicine
A 40-year-old Japanese woman presented to our hospital with general fatigue and muscle weakness. She had a history of premature loss of deciduous teeth at 4 years old, her serum alkaline phosphatase (ALP) activity was as low as 91 U/L, and radiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69706353165914f6872b0171e226729
https://pubmed.ncbi.nlm.nih.gov/31787692
https://pubmed.ncbi.nlm.nih.gov/31787692
Autor:
Hiromi Kataoka, Daisuke Aotani, Kento Ogawa, Eiji Kubota, Tomohiro Tanaka, Tingting Guo, Hiroyuki Koyama, Takashi Yagi
Publikováno v:
Diabetes. 68
Background: Recent increase in the relative proportion of cancer death in diabetic patients has become a major issue. A hypoglycemic agent, sodium-glucose cotransporter (SGLT) 2 inhibitor has attracted attention because of its potency in reducing car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e699712f2ffa717d5e0d8222f3e786d
https://doi.org/10.2337/db19-166-lb
https://doi.org/10.2337/db19-166-lb
Autor:
Hiroshi Iwakura, Daisuke Aotani, Toru Kusakabe, Kazunobu Sawamoto, Tomo Unzai, Kazuwa Nakao, Tomohiro Tanaka, Yohei Ogino, Tingting Guo, Kentaro Kaneko, Takashi Miyazawa, Mami Matsumoto, Hiroaki Masuzaki, Yasuhiko Minokoshi, Nobuya Inagaki
Publikováno v:
Neuroscience letters. 714
Background Cannabinoid receptor 1 (CB1R) is a GPCR expressed widely in the brain as well as in peripheral metabolic organs. Although pharmacological blockade of CB1R has been effective for the treatment of obesity and tobacco addiction, precise distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b72a902bafe59a37d576854b4dd36d0
https://pubmed.ncbi.nlm.nih.gov/31634502
https://pubmed.ncbi.nlm.nih.gov/31634502