Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Daisuke, Ohshima"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 153, Iss 3, Pp 130-141 (2023)
Diabetes mellitus is a prevalent risk factor for congestive heart failure. Diabetic cardiomyopathy patients present with left ventricular (LV) diastolic dysfunction at an early stage, then systolic dysfunction as the disease progresses. The mechanism
Externí odkaz:
https://doaj.org/article/779ad662343d45e9bfd73c537184376e
Autor:
Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The stromal fibroblast population in the colon is composed of heterogeneous and distinct cell subtypes that play a crucial role in the development of colitis and colon cancer. Here the authors generate IL-11 reporter mice and characterize the origin
Externí odkaz:
https://doaj.org/article/3db3ac661ebb40e88567f28d3824a2f8
Autor:
Toshihiko Kobayashi, Daisuke Ohshima, Noriko Toyama-Sorimachi, Hitomi Karyu, Dat Nguyen-Tien, Shiho Shimabukuro-Demoto, Reiko Yoshida-Sugitani
Publikováno v:
International Immunology. 33:399-406
Solute carrier family 15 member 4 (SLC15A4) is an endolysosome-resident amino acid transporter that regulates innate immune responses, and is genetically associated with inflammatory diseases such as systemic lupus erythematosus (SLE) and colitis. SL
Autor:
Daisuke Ohshima, Kyoko Arimoto-Matsuzaki, Taichiro Tomida, Mutsuhiro Takekawa, Kazuhisa Ichikawa
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 6, p e1004326 (2015)
Stress granules (SGs) are non-membranous cytoplasmic aggregates of mRNAs and related proteins, assembled in response to environmental stresses such as heat shock, hypoxia, endoplasmic reticulum (ER) stress, chemicals (e.g. arsenite), and viral infect
Externí odkaz:
https://doaj.org/article/07a2c2ccdb4d4b34b4a0f51b942e472d
Autor:
Daisuke Ohshima, Kazuhisa Ichikawa
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127633 (2015)
The activated transcription factor NF-κB shuttles between the cytoplasm and the nucleus resulting in the oscillation of nuclear NF-κB (NF-κBn). The oscillation pattern of NF-κBn is implicated in the regulation of gene expression profiles. Using c
Externí odkaz:
https://doaj.org/article/82f987501e7741c2adb219671784136b
Autor:
Daisuke Ohshima, Masatoshi Tokushima, Akio Ukita, Akihiro Noriki, Takeru Amano, Koichi Takemura, Daisuke Okamoto, Daisuke Shimura, Jun Ushida, Tsuyoshi Aoki
Publikováno v:
2021 International Conference on Electronics Packaging (ICEP).
We propose silicon (Si)-photonics-embedded interposers to minimize the Si photonics chip size and achieve highly precise optical fiber alignment. The interposers are organic interposer substrates that have Si photonics transceiver dies buried in the
Autor:
Daisuke Ohshima, Kazuhisa Ichikawa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109895 (2014)
The transcription factor NF-κB shuttles between the cytoplasm and the nucleus, and nuclear NF-κB is known to oscillate with a cycle of 1.5-2.5 h following the application of external stimuli. Oscillation pattern of NF-κB is implicated in regulatio
Externí odkaz:
https://doaj.org/article/a9bf0ec765c94bedae46900be267c9b4
Autor:
Kouji Matsushima, Mizuho Hasegawa, Eri Nakamura, Kazutoshi Shibuya, Takashi Nishina, Daisuke Ohshima, Wakami Takeda, Norihiro Tada, Chiharu Nishiyama, Tetuo Mikami, Mizuho Nakayama, Shigeyuki Shichino, Hiroyasu Nakano, Mika Kawauchi, Masato Ohtsuka, Hideo Yagita, Naohiro Inohara, Satomi Adachi-Akahane, Masanobu Oshima, Soh Yamazaki, Yuko Kojima, Yutaka Deguchi, Satoshi Ueha
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Interleukin (IL)-11 is a member of the IL-6 family of cytokines and is involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood. To characterize
Autor:
Hiroyasu Nakano, Yutaka Deguchi, Eri Nakamura, Masato Ohtsuka, Kazutoshi Shibuya, Takashi Nishina, Hideo Yagita, Daisuke Ohshima, Mizuho Nakayama, Mika Kawauchi, Wakami Takeda, Norihiro Tada, Mizuho Hasegawa, Chiharu Nishiyama, Naohiro Inohara, Satomi Adachi-Akahane, Masanobu Oshima, Soh Yamazaki, Yuko Kojima, Tetuo Mikami
SUMMARYInterleukin (IL)-11 is a member of the IL-6 family of cytokines and involved in multiple cellular responses, including tumor development. However, the origin and functions of IL-11-producing (IL-11+) cells are not fully understood. To characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e3cada8a9e1f5b821661058025f529
Autor:
Yuto, Tei, Yoshinori, Mikami, Masanori, Ito, Taichiro, Tomida, Daisuke, Ohshima, Yuichi, Hori, Satomi, Adachi-Akahane
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Dry eye–induced chronic ocular pain is also called ocular neuropathic pain. However, details of the pathogenic mechanism remain unknown. The purpose of this study was to elucidate the pathogenic mechanism of dry eye–induced chronic pain i