Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Daisuke, Nakada"'
Autor:
Yu-Jung Tseng, Yuki Kageyama, Rebecca L. Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A. Hoegenauer, Jonathan Tiessen, Mackenzie H. Smith, Hidetaka Uryu, Koichi Takahashi, James F. Martin, Md Abul Hassan Samee, Daisuke Nakada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hematopoietic stem cells (HSCs) are capable of regenerating the blood system, but the instructive cues that direct HSCs to regenerate particular lineages lost to the injury remain elusive. Here, we show that iron is increasingly taken up by
Externí odkaz:
https://doaj.org/article/e2f9fc0f56c34621b4e2cc5d8cfc94a7
Autor:
Koichi Takahashi1 ktakahashi@mdanderson.org, Daisuke Nakada2, Goodell, Margaret3 goodell@bcm.edu
Publikováno v:
Journal of Clinical Investigation. Oct2024, Vol. 134 Issue 19, p1-10. 10p.
Autor:
Yuewei Wang, Tong Huo, Yu-Jung Tseng, Lan Dang, Zhili Yu, Wenjuan Yu, Zachary Foulks, Rebecca L. Murdaugh, Steven J. Ludtke, Daisuke Nakada, Zhao Wang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Wang et al characterise platelets in a mouse model of acute myeloid leukemia (AML) using Cryo-electron tomography (Cryo-ET) and find that 23% of platelets in pre-leukemic cells exhibit abnormal, round mitochondria with unfolded cristae. They also det
Externí odkaz:
https://doaj.org/article/b644d925817f401c8f961301fc653c0d
Autor:
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A. Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P. Patel, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge Cortes, Kapil Bhalla, Guillermo Garcia-Manero, Hagop Kantarjian, Marina Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P. Andrew Futreal, Koichi Takahashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Understanding the evolutionary trajectory of cancer samples may enable understanding resistance to treatment. Here, the authors used single cell sequencing of a cohort of acute myeloid leukemia tumours and identify features of linear and branching ev
Externí odkaz:
https://doaj.org/article/c334158e79f74f09bd8df84c3b7562c1
Autor:
Tianyuan Hu, Ayumi Kitano, Victor Luu, Brian Dawson, Kevin A. Hoegenauer, Brendan H. Lee, Daisuke Nakada
Publikováno v:
Stem Cell Reports, Vol 13, Iss 3, Pp 545-558 (2019)
Summary: Bone marrow stromal cells (BMSCs) that express high levels of stem cell factor (SCF) and CXC chemokine ligand 12 (CXCL12) are one crucial component of the hematopoietic stem cell (HSC) niche. While the secreted factors produced by BMSCs to s
Externí odkaz:
https://doaj.org/article/c8c428a2d16c435485b011926466eb70
Autor:
Richard H. Chapple, Yu-Jung Tseng, Tianyuan Hu, Ayumi Kitano, Makiko Takeichi, Kevin A. Hoegenauer, Daisuke Nakada
Publikováno v:
Blood Advances, Vol 2, Iss 11, Pp 1220-1228 (2018)
Abstract: Characterization of hematopoietic stem cells (HSCs) has advanced largely owing to transplantation assays, in which the developmental potential of HSCs is assessed generally in nonhomeostatic conditions. These studies established that adult
Externí odkaz:
https://doaj.org/article/17faef94eeb64608a045a97281fc5f72
Publikováno v:
Genes & Development. 36:887-900
The polycomb complex component Bmi1 promotes the maintenance of stem cells in multiple postnatal tissues, partly by negatively regulating the expression of p16Ink4a and p19Arf, tumor suppressors associated with cellular senescence. However, deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59af54c523bdd96b1273e6363c91274c
https://doi.org/10.1101/gad.349917.122
https://doi.org/10.1101/gad.349917.122
Autor:
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A. Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P. Patel, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge Cortes, Kapil Bhalla, Guillermo Garcia-Manero, Hagop Kantarjian, Marina Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P. Andrew Futreal, Koichi Takahashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6d484e9b6c754f81b3920dc715a23a3d
Autor:
Michael C. Gundry, Lorenzo Brunetti, Angelique Lin, Allison E. Mayle, Ayumi Kitano, Dimitrios Wagner, Joanne I. Hsu, Kevin A. Hoegenauer, Cliona M. Rooney, Margaret A. Goodell, Daisuke Nakada
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1453-1461 (2016)
Summary: Our understanding of the mechanisms that regulate hematopoietic stem/progenitor cells (HSPCs) has been advanced by the ability to genetically manipulate mice; however, germline modification is time consuming and expensive. Here, we describe
Externí odkaz:
https://doaj.org/article/a84ef1ca22b448db80fbb63ddf1b86b6
Autor:
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A. Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P. Patel, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge Cortes, Kapil Bhalla, Guillermo Garcia-Manero, Hagop Kantarjian, Marina Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P. Andrew Futreal, Koichi Takahashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-19902-7
Externí odkaz:
https://doaj.org/article/a2fbc9c066164b95929bcb1212c87e28