Engineered Escherichia coli platforms for tyrosine-derivative production from phenylalanine using phenylalanine hydroxylase and tetrahydrobiopterin-regeneration system

Autor: Yasuharu Satoh, Keita Fukui, Daisuke Koma, Ning Shen, Taek Soon Lee

Publikováno v: Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-13 (2023)

Abstract Background Aromatic compounds derived from tyrosine are important and diverse chemicals that have industrial and commercial applications. Although these aromatic compounds can be obtained by extraction from natural producers, their growth is

Externí odkaz: https://doaj.org/article/cac91dd9dbd94188941cfd1797d88d71

Chromosome Engineering To Generate Plasmid-Free Phenylalanine- and Tyrosine-Overproducing Escherichia coli Strains That Can Be Applied in the Generation of Aromatic-Compound-Producing Bacteria

Autor: Eiji Nagamori, Hiroyuki Ohashi, Takashi Ohmoto, Hayato Yamanaka, Eisuke Yoshida, Kunihiko Moriyoshi, Takahiro Kishida, Daisuke Koma

Publikováno v: Applied and Environmental Microbiology. 86

Many phenylalanine- and tyrosine-producing strains have used plasmid-based overexpression of pathway genes. The resulting strains achieved high titers and yields of phenylalanine and tyrosine. Chromosomally engineered, plasmid-free producers have sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c32df361397416e723a7344e7ed7cdea
https://doi.org/10.1128/aem.00525-20

Promoted performance of microbial fuel cells using Escherichia coli cells with multiple-knockout of central metabolism genes

Autor: Masayuki Azuma, Ryota Kikuchi, Takashi Ohmoto, Kazuma Terao, Taichi Kawaguchi, Yoshihiro Ojima, Daisuke Koma, Saki Fukui

Publikováno v: Bioprocess and biosystems engineering. 43(2)

The effect of central metabolic activity of Escherichia coli cells acting as biocatalysts on the performance of microbial fuel cells (MFCs) was studied with glucose used as the energy source. Milliliter-scale two-chambered MFCs were used with 2-hydro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e00345ab6c50c2ed35203240f691047
https://pubmed.ncbi.nlm.nih.gov/31606755

Biological Production of Lactobionic Acid for Food

Autor: Daisuke Koma, Hiromi Murakami, Shigemitsu Tanaka, Taro Kiso, Hirofumi Nakano, Takaaki Kiryu

Publikováno v: Nippon Shokuhin Kagaku Kogaku Kaishi. 63:137-141

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::071ad0be1ffd848b5ff6432ee9908d4a
https://doi.org/10.3136/nskkk.63.137

Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway

Autor: Leanne Jade G. Chan, Qijun Hu, Lars K. Nielsen, Christopher J. Petzold, Jay D. Keasling, Claudia E. Vickers, Jorge Alonso-Gutierrez, Yuchen Yang, Taek Soon Lee, Paul D. Adams, Daisuke Koma

Publikováno v: Alonso-Gutierrez, J, Koma, D, Hu, Q, Yang, Y, Chan, L J G, Petzold, C J, Adams, P D, Vickers, C E, Nielsen, L K, Keasling, J D & Lee, T S 2018, ' Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway ', Biotechnology and Bioengineering, vol. 115, no. 4, pp. 1000-1013 . https://doi.org/10.1002/bit.26530
Biotechnology and bioengineering, vol 115, iss 4
Alonso-Gutierrez, J; Koma, D; Hu, Q; Yang, Y; Chan, LJG; Petzold, CJ; et al.(2018). Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway. Biotechnology and Bioengineering, 115(4), 1000-1013. doi: 10.1002/bit.26530. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/3f32n3dx

© 2017 Wiley Periodicals, Inc. Escherichia coli has been the organism of choice for the production of different chemicals by engineering native and heterologous pathways. In the present study, we simultaneously address some of the main issues associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ea0f3c0a504a5e1a9515292663373a
https://orbit.dtu.dk/en/publications/3cded7e7-99c0-42c9-821f-08c1d88b35d7