Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Daisuke, Kohno"'
Autor:
Naoki Kuramoto, Kazuhiro Nomura, Daisuke Kohno, Tadahiro Kitamura, Gerard Karsenty, Tetsuya Hosooka, Wataru Ogawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Phosphatidylinositol 3-kinase (PI3K) plays an important role in protein metabolism and cell growth. We here show that mice (M-PDK1KO mice) with skeletal muscle–specific deficiency of 3′-phosphoinositide–dependent kinase 1 (PDK1), a key
Externí odkaz:
https://doaj.org/article/0c29e639e6c14990af1ddb5203233689
Autor:
Teppei Fujikawa, Yun-Hee Choi, Dong Joo Yang, Dong Min Shin, Jose Donato, Daisuke Kohno, Charlotte E. Lee, Carol F. Elias, Syann Lee, Ki Woo Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-9 (2019)
Metabolism: Enzymatic subunit essential to brain’s glucose responses A particular subunit of a critical signaling enzyme is needed for neurons inside the brain’s hypothalamus to properly regulate energy metabolism. Ki Woo Kim from Yonsei Universi
Externí odkaz:
https://doaj.org/article/140c2a65c43e419cb301c26994d328f7
Autor:
Sho Matsui, Tsutomu Sasaki, Daisuke Kohno, Keisuke Yaku, Ayumu Inutsuka, Hiromi Yokota-Hashimoto, Osamu Kikuchi, Takayoshi Suga, Masaki Kobayashi, Akihiro Yamanaka, Akihiro Harada, Takashi Nakagawa, Tatsushi Onaka, Tadahiro Kitamura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
SIRT1 is a NAD+-dependent deacetylase whose functions have been linked to organismal longevity, aging and metabolism. Here, Matsui and colleagues show that neuronal SIRT1 can affect nutrient-related dietary choice in mice, and this effect is mediated
Externí odkaz:
https://doaj.org/article/0e6908642176438fbd24e41a6c8e07f1
Autor:
Xavier Brenachot, Giorgio Ramadori, Rafael M. Ioris, Christelle Veyrat-Durebex, Jordi Altirriba, Ebru Aras, Sanda Ljubicic, Daisuke Kohno, Salvatore Fabbiano, Sophie Clement, Nicolas Goossens, Mirko Trajkovski, Sheila Harroch, Francesco Negro, Roberto Coppari
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
During obesity, chronic inflammation leads to insulin resistance and diabetes. Here, Brenachot et al. show that Protein Tyrosine Phosphatase Receptor Gamma is upregulated in obesity by inflammatory signals and correlates with insulin resistance in hu
Externí odkaz:
https://doaj.org/article/c9087c97e4584399b00b49105c3d6c1d
Publikováno v:
Journal of Obesity & Metabolic Syndrome; Dec2023, Vol. 32 Issue 4, p303-311, 9p
Autor:
Daisuke Kohno, Gerard Karsenty, Wataru Ogawa, Kazuhiro Nomura, Tetsuya Hosooka, Naoki Kuramoto, Tadahiro Kitamura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Phosphatidylinositol 3-kinase (PI3K) plays an important role in protein metabolism and cell growth. We here show that mice (M-PDK1KO mice) with skeletal muscle–specific deficiency of 3′-phosphoinositide–dependent kinase 1 (PDK1), a key componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8651d9df35310104b3bafb746cfbe8fe
https://doaj.org/article/0c29e639e6c14990af1ddb5203233689
https://doaj.org/article/0c29e639e6c14990af1ddb5203233689
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
The hypothalamic feeding center plays an important role in energy homeostasis. In the feeding center, whole-body energy signals including hormones and nutrients are sensed, processed, and integrated. As a result, food intake and energy expenditure ar
Externí odkaz:
https://doaj.org/article/ee070cfeb16e457cb8758781ca938b23
Autor:
Tadahiro Kitamura, Kazuko Saeki, Yoshio Fujitani, Tsutomu Sasaki, Hirotaka Watada, Takehiko Yokomizo, Daisuke Kohno, Tomoaki Koga, Takeshi Miyatsuka, Toshiaki Okuno, Saiko Kazuno, Airi Jo-Watanabe, Ayako Fukunaka, Hirotsugu Uzawa
Publikováno v:
The FASEB Journal. 34:13949-13958
Obesity is a health problem worldwide, and brown adipose tissue (BAT) is important for energy expenditure. Here, we explored the role of leukotriene A4 hydrolase (LTA4 H), a key enzyme in the synthesis of the lipid mediator leukotriene B4 (LTB4 ), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e66973eb750df029b28449162b79732
https://doi.org/10.1096/fj.202001148r
https://doi.org/10.1096/fj.202001148r
Autor:
Atsushi Ozawa, Daisuke Kohno, Hideo Akiyama, Akihiro Harada, Nobuyuki Shibusawa, Masanobu Yamada, Tsutomu Sasaki, Sayaka Yamada, Hideaki Yokoo, Yuri Kondo, Kazuhiko Horiguchi, Yasuyo Nakajima, Kazuma Saito, Tadahiro Kitamura, Battsetseg Buyandalai
Publikováno v:
Thyroid.
Background Thyrotropin-releasing hormone (TRH) was the first hypothalamic hormone isolated that stimulates pituitary thyroid-stimulating hormone (TSH) secretion. TRH was also later found to be a stimulator of pituitary prolactin and distributed throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94209e5c9cf7bc4e00ffdf5a6dcf86d1
https://doi.org/10.1089/thy.2021.0444
https://doi.org/10.1089/thy.2021.0444
Autor:
Yuri Kondo, Atsushi Ozawa, Daisuke Kohno, Kazuhiko Horiguchi, Nobuyuki Shibusawa, Hideaki Yokoo, Tadahiro Kitamura, Yamada Masanobu
Publikováno v:
Journal of the Endocrine Society. 6:A485-A485
Objectives Thyrotropin-releasing hormone (TRH) was the first hypothalamic hormone isolated that stimulates pituitary thyroid-stimulating hormone (TSH) secretion. TRH was later found to be distributed throughout the brain, gastrointestinal tract and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1974db4bc8799980fdf374a4693ed09a
https://doi.org/10.1210/jendso/bvac150.1007
https://doi.org/10.1210/jendso/bvac150.1007