Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daishiro Kobayashi"'
Autor:
Dr. Daishiro Kobayashi, Dr. Masaya Denda, Junya Hayashi, Kota Hidaka, Yutaka Kohmura, Dr. Takaaki Tsunematsu, Dr. Kohei Nishino, Dr. Harunori Yoshikawa, Dr. Kento Ohkawachi, Dr. Kiyomi Nigorikawa, Dr. Tetsuro Yoshimaru, Prof. Naozumi Ishimaru, Prof. Wataru Nomura, Prof. Toyomasa Katagiri, Prof. Hidetaka Kosako, Prof. Akira Otaka
Publikováno v:
ChemistryEurope, Vol 2, Iss 3-4, Pp n/a-n/a (2024)
Abstract A method was developed that enables the magnesium chloride (MgCl2)‐activated S‐acetamidomethyl cysteine sulfoxide (Cys(Acm)(O)) to induce the sp2(C−H) sulfenylation of the indole of Trp residues. The reaction operates under mild acidic
Externí odkaz:
https://doaj.org/article/222723dbb8234764ba71bc9a59b8809f
Autor:
Daishiro Kobayashi, Eisuke Kuraoka, Junya Hayashi, Takuma Yasuda, Yutaka Kohmura, Masaya Denda, Norio Harada, Nobuya Inagaki, Akira Otaka
Publikováno v:
ACS Medicinal Chemistry Letters. 13(7):1125-1130
Lipidation of peptides is a promising means of modification that can improve the therapeutic character of biologically active peptides. Here a novel lipidation protocol for peptides is described. The C−H sulfenylation of indole in peptides using S-
Autor:
Kento Ohkawachi, Kaito Anzaki, Daishiro Kobayashi, Ryuji Kyan, Takuma Yasuda, Masaya Denda, Norio Harada, Akira Shigenaga, Nobuya Inagaki, Akira Otaka
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Kento Ohkawachi, Kaito Anzaki, Daishiro Kobayashi, Ryuji Kyan, Takuma Yasuda, Masaya Denda, Norio Harada, Akira Shigenaga, Nobuya Inagaki, Akira Otaka
Publikováno v:
Chemistry – A European Journal. 29
A tyrosine (Tyr)- or tryptophan (Trp)-selective metal-free C−H sulfenylation reaction using an acid-activated Sacetamidomethyl cysteine (Cys) sulfoxide, Cys(Acm)(O), has been achieved. The dually protonated intermediate produced from the Cys(Acm)(O
Autor:
Eisuke Kuraoka, Toshimichi Fujiwara, Masaya Denda, Daishiro Kobayashi, Akira Otaka, Yutaka Kohmura, Toshihiko Sugiki
Publikováno v:
Chemistry – A European Journal. 27:14092-14099
Covalent linking of side chains provides a method to produce cyclic or stapling peptides that are important in developing peptide-based drugs. A variety of crosslinking formats contribute to fixing the active conformer and prolonging its biological a
Autor:
Masaya Denda, Kenzo Yamatsugu, Akira Shigenaga, Daishiro Kobayashi, Motomu Kanai, Akira Otaka, Kento Ohkawachi, Kyohei Morimoto
Publikováno v:
Organic Letters. 22:5289-5293
Sulfanylmethyl-installed dimethylaminopyridine, 2-sulfanylmethyl-4-dimthylaminopyridine (SMDMAP) (2), has an acidic thiol group comparable to that in aryl thiols due to the formation of a zwitterion consisting of a thiolate anion and a pyridinium cat
Publikováno v:
Organicbiomolecular chemistry. 18(42)
Ring-opening by CuSO4 of a 1,3-thiazolidine carbonyl structure (Thz) as an N-terminal cysteine (Cys) residue revealed that an intramolecular S-acetamidomethyl cysteine (Cys(Acm)) can also be deprotected with concomitant formation of a disulphide bond
Autor:
Yuko Aono, Yoshiki Nakamura, Shun Akaike, Masanori Hiratsuka, Tohru Hayakawa, Daishiro Kobayashi, Atsushi Hirata
Publikováno v:
Diamond and Related Materials. 61:109-114
In orthodontics, it is important to reduce the static friction between brackets and wires in order to enable easy tooth movement. The goal of the present study was to deposit diamond-like carbon (DLC), fluorine-doped DLC (F-DLC), and silicon-doped DL
Autor:
Tohru Hayakawa, Daishiro Kobayashi, Yoshiki Nakamura, Shun Akaike, Yuko Aono, Atsushi Hirata, Masanori Hiratsuka
Publikováno v:
Dental Materials Journal. 34:888-895
In orthodontics, a reduction in static friction between the brackets and wire is important to enable easy tooth movement. The aim of this study was to examine the effects of a homogeneous diamond-like carbon (DLC) coating on the whole surfaces of slo
Publikováno v:
Therapeutic Apheresis and Dialysis. 11:74-77
A 64-year-old man was admitted because of abdominal fullness, edema and anorexia. He had come to our hospital for treatment of liver cirrhosis and diabetic nephropathy for 1 year. We started diuretics and human albumin intravenous administration. Alt