Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daisaku Tomioka"'
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective A dual inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor 1 receptor (IGF-1R), TAE226, was evaluated in a panel of cancer cell lines, MIA PaCa-2 human pancreatic tumor and 4T1 murine breast tumor models. The pr
Externí odkaz:
https://doaj.org/article/f6300bd517b0413780d8f644353baa66
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Objective A dual inhibitor of focal adhesion kinase (FAK) and insulin-like growth factor 1 receptor (IGF-1R), TAE226, was evaluated in a panel of cancer cell lines, MIA PaCa-2 human pancreatic tumor and 4T1 murine breast tumor models. The profiling d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b9e17a5b801d86d731bdfbaf1b60f8
https://doi.org/10.1186/s13104-019-4389-7
https://doi.org/10.1186/s13104-019-4389-7
Additional file 2: Table S2. Effects of TAE226 on MIA PaCa-2 subcutaneous tumor growth and body weight change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4f85b0b95c10e3b27dd1248af10808
Publikováno v:
Cancer Gene Therapy. 11:419-430
Hepatocyte growth factor (HGF) is involved in malignant behavior of cancer cells by enhancing invasion and metastasis. We earlier found that NK4, a four-kringle fragment of HGF, functions as both an HGF antagonist and an angiogenesis inhibitor. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6562cee82bea43f84565e9b6c7c4644d
https://doi.org/10.1038/sj.cgt.7700705
https://doi.org/10.1038/sj.cgt.7700705
Publikováno v:
Biochemical and biophysical research communications. 358(1)
NK4, originally prepared as a competitive antagonist for hepatocyte growth factor (HGF), is a bifunctional molecule that acts as an HGF-antagonist and angiogenesis inhibitor. When the expression plasmid for NK4 gene was administered into mice by hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0741b3f55ab776901190affedd9d3908
https://pubmed.ncbi.nlm.nih.gov/17467663
https://pubmed.ncbi.nlm.nih.gov/17467663
Autor:
Daisaku Tomioka, Kazuhiko Bessho, Kunio Matsumoto, Saho Yoshida, Kunihiko Yoshikawa, Toshikazu Nakamura, Satoshi Itami
Publikováno v:
Growth factors (Chur, Switzerland). 22(2)
We examined effects of recombinant hepatocyte growth factor (HGF) on cutaneous wound healing, using a full-thickness cutaneous excision model in diabetic mice. Topical administration of HGF, as well as basic fibroblast growth factor (bFGF), promoted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d2748d7403f0336f84fa12e9ed226e
https://pubmed.ncbi.nlm.nih.gov/15253387
https://pubmed.ncbi.nlm.nih.gov/15253387