Výsledky vyhledávání - "Daisaku Nakamura"

Design, Synthesis, and Preliminary Evaluation of SPECT Probes for Imaging β-Amyloid in Alzheimer's Disease Affected Brain

Autor: Yoshinari Shoyama, Daisaku Nakamura, Takako Onishi, Yasushi Arano, Akihiro Tanaka, Yoshifumi Maya, Shigeyuki Tanifuji, Hiroki Matsumoto, Yuki Okumura, Izawa Akihiro

Publikováno v: ACS chemical neuroscience. 9(6)

In this study, we synthesized of a series of 2-phenyl- and 2-pyridyl-imidazo[1,2-a]pyridine derivatives and examine their suitability as novel probes for single-photon emission computed tomography (SPECT)-based imaging of β-amyloid (Aβ). Among the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25730ad2fd64fc75d1fcd83d1e711672
https://pubmed.ncbi.nlm.nih.gov/29580057

Zobrazit plný text záznamu

Novel asymmetric dealkoxycarbonylation of 3-oxo-8-azabicyclo[3.2.1]-octane-2,4-dicar☐ylates using porcine liver esterase: A new route to (−)-anhydroecgonine methyl ester

Autor: Manabu Node, Takahiro Katoh, Kiyoharu Nishide, Daisaku Nakamura, Soichi Nakamura

Publikováno v: Tetrahedron Letters. 40:5357-5360

The porcine liver esterase-catalyzed dealkoxycarbonylation of 8-benzyl-3-oxo-8-azabicyclo[3.2.1]octane-2,4-dicar☐ylates (4) was found to give high enantiomeric excess of the desymmetrized keto ester (5). This novel dealkoxyl-carbonylation opened a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e81df706ca4a3a193bb2e0bc145330e1
https://doi.org/10.1016/s0040-4039(99)00976-4

Zobrazit plný text záznamu

Lipase-catalyzed asymmetric demethoxycarbonylation: Formal syntheses of (+)-carbacyclin, (−)-ajmalicine, and (−)-tetrahydroalstonine

Autor: T. Inoue, Mamoru Araki, Manabu Node, Daisaku Nakamura, Kiyoharu Nishide

Publikováno v: Tetrahedron: Asymmetry. 9:157-167

Both enantiomers of C 2 -symmetric dimethyl 3,7-dihydroxybicyclo[3.3.0]-octa-2,6-diene-2,6-dicarboxylate 3 were prepared in enantiomerically pure form from symmetric tetraester 1 by the lipase-catalyzed demethoxycarbonylation, respectively. Double as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee13e0d6b39248b4107f61b2409236e
https://doi.org/10.1016/s0957-4166(97)00616-2

Zobrazit plný text záznamu

A new entry for the deprotection of monothioacetals and dithioacetals: Silver nitrite - iodine system

Autor: K. Yokota, Kaoru Fuji, T. Sumiya, Manabu Node, Masaru Ueda, Kiyoharu Nishide, Daisaku Nakamura

Publikováno v: Tetrahedron Letters. 34:3425-3428

A new reagent system (silver nitrite-iodine) was developed for demonothioacetalization and dedithioacetalization reactions. The reaction using this reagent afforded the parent carbonyl compound in excellent yield under mild conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a9c0ef528a5496ee34d99993cb240bb
https://doi.org/10.1016/s0040-4039(00)79173-8

Zobrazit plný text záznamu