Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Dairu Liu"'
Autor:
Yuan Yao, Fan Li, Mao Zhang, Li Jin, Peng Xie, Dairu Liu, Junxia Zhang, Xinli Hu, Fengxiang Lv, Haibao Shang, Wen Zheng, Xueting Sun, Jiaxin Duanmu, Fujian Wu, Feng Lan, Rui-Ping Xiao, Yan Zhang
Publikováno v:
Circ Res
Background: CaMKII (Ca 2+ /calmodulin-dependent kinase II) plays a central role in cardiac ischemia/reperfusion (I/R) injury—an important therapeutic target for ischemic heart disease. In the heart, CaMKII-δ is the predominant isoform and further
Publikováno v:
British Journal of Pharmacology
Excessive death of cardiac myocytes leads to many cardiac diseases, including myocardial infarction, arrhythmia, heart failure and sudden cardiac death. For the last several decades, most work on cell death has focused on apoptosis, which is generall
Autor:
Li Jin, Chuan-Yun Li, Feng Lan, Xiaolu Shi, Yajie Tang, Lei Song, Hua Gao, Mao Zhang, Rui-Ping Xiao, Yan Zhang, Peng Yu, Xinli Hu, Dairu Liu, Yunhu Song, Jinghao Liu, Xiaoming Zhong, Fujian Wu, Jun Qin, Yun Liu
Publikováno v:
Nature cell biology. 21(9)
Ca2+/calmodulin-dependent kinase II (CaMKII) is a multifunctional serine/threonine kinase family, and its δ isoform is predominant in the heart. Excessive CaMKII activation plays a pivotal role in the pathogenesis of severe heart conditions, includi