Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dain W. Jacob"'
Autor:
Anna M. Gonsalves, Sarah E. Baker, Dain W. Jacob, Jennifer L. Harper, Camila M. Manrique‐Acevedo, Jacqueline K. Limberg
Publikováno v:
Physiological Reports, Vol 12, Iss 17, Pp n/a-n/a (2024)
Abstract Endothelin‐1 (ET‐1) and its receptors are linked to increases in sensitivity of the chemoreceptors to hypoxic stress and the development of hypertension in preclinical models. We hypothesized ET receptor antagonism would lower resting bl
Externí odkaz:
https://doaj.org/article/e026846d30c449f5a3ad217d52f3d2aa
Autor:
Sara E. Mascone, Dain W. Jacob, Lauren E. Eagan, Jennifer L. Harper, Jacqueline K. Limberg, Sushant M. Ranadive
Publikováno v:
Experimental Physiology, Vol 108, Iss 12, Pp 1481-1489 (2023)
Abstract The present study evaluated cardiovagal baroreflex sensitivity (BRS) across the menstrual/pill cycle in naturally menstruating women (NAT women) and women using oral hormonal contraceptives (OCP women). In 21 NAT women (23 ± 4 years old) an
Externí odkaz:
https://doaj.org/article/91f5ba2ea11f4f07bf9dbd03044491f9
Autor:
Jacqueline K. Limberg, Sarah E. Baker, Elizabeth P. Ott, Dain W. Jacob, Zachariah M. Scruggs, Jennifer L. Harper, Camila M. Manrique-Acevedo
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(4)
Repeat exposures to low oxygen (intermittent hypoxia, IH), like that observed in sleep apnea, elicit increases in muscle sympathetic nerve activity (MSNA) and blood pressure (BP) in men. Endothelin (ET) receptor antagonists can attenuate the sympathe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36192d8e5b7508b856ec8995dfede9a2
https://pubmed.ncbi.nlm.nih.gov/35952348
https://pubmed.ncbi.nlm.nih.gov/35952348
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08a8d544b70d957963cf99fd220dc88
https://doi.org/10.1096/fasebj.2022.36.s1.l7666
https://doi.org/10.1096/fasebj.2022.36.s1.l7666
Publikováno v:
Am J Physiol Heart Circ Physiol
Acute increases in sympathetic nervous system activity (SNA) often elicit peripheral vasoconstriction and increases in blood pressure (BP). Given sympathetic support of BP is modulated by ovarian sex hormones (e.g., estradiol), we sought to examine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9e4390b5a4d8e7c80f8da5e5edf780
https://europepmc.org/articles/PMC9142154/
https://europepmc.org/articles/PMC9142154/
Autor:
J. Kevin Shoemaker, Walter W. Holbein, Sarah E. Baker, Dain W. Jacob, Jacqueline K. Limberg, Zachariah M. Scruggs, Elizabeth P. Ott
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Bone and Joint Institute
Bone and Joint Institute
We examined the effect of acute intermittent hypoxia (IH) on sympathetic neural firing patterns and the role of the carotid chemoreceptors. We hypothesized exposure to acute IH would increase muscle sympathetic nerve activity (MSNA) via an increase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764c7b7accea6388b0f8017f0654b535
https://doi.org/10.1152/ajpregu.00004.2020
https://doi.org/10.1152/ajpregu.00004.2020
Autor:
Jennifer L. Harper, Dain W. Jacob, Jacqueline K. Limberg, Elizabeth P. Ott, Clayton L. Ivie, Jane S. Edmunds, Camila Manrique-Acevedo, Sarah E. Baker
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Sex-related differences in respiratory modulation of sympathetic activity have been observed in rodent models of sleep apnea [intermittent hypoxia (IH)]. In light of sex disparities in the respiratory response to acute IH in humans as well as changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211b5cf99f605481a3ff7c8ff10f5e24
https://europepmc.org/articles/PMC8714811/
https://europepmc.org/articles/PMC8714811/
Publikováno v:
Exp Physiol
NEW FINDINGS What is the central question of this study? Sympathetically mediated vasoconstriction is preserved during hypoxaemia in humans, but our understanding of vascular control comes from predominantly male cohorts. We tested the hypothesis tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e45de12284a1811e87ec7c7bde12a1e
https://europepmc.org/articles/PMC8324557/
https://europepmc.org/articles/PMC8324557/
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c955e0d512c2e5a48cf104b5e61b187c
https://doi.org/10.1096/fasebj.2021.35.s1.01493
https://doi.org/10.1096/fasebj.2021.35.s1.01493
Autor:
Camila Manrique-Acevedo, Dain W. Jacob, Jaume Padilla, Jaqueline K Limberg, Brian Shariffi, Gavin Power, Rogério Nogueira Soares, Jennifer L. Harper, James A Smith
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Herein we report in a sample of healthy young men ( n = 14) and women ( n = 12) that hyperinsulinemia induces time-dependent decreases in total peripheral resistance and its contribution to the maintenance of blood pressure. In the same participants,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c01bc0bb36f7ba56e583cbf1ff40be
https://europepmc.org/articles/PMC8285614/
https://europepmc.org/articles/PMC8285614/