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A Latent Propriospinal Network Can Restore Diaphragm Function after High Cervical Spinal Cord Injury
Autor:
Jared M. Cregg, Kevin A. Chu, Lydia E. Hager, Rachel S.J. Maggard, Daimen R. Stoltz, Michaela Edmond, Warren J. Alilain, Polyxeni Philippidou, Lynn T. Landmesser, Jerry Silver
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 654-665 (2017)
Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excita
Externí odkaz:
https://doaj.org/article/994ec695c1454270848206c7b3bfa16f