Výsledky vyhledávání - "Dailan Danforth"

Phase Ia dose escalation study of OBP-801, a cyclic depsipeptide class I histone deacetylase inhibitor, in patients with advanced solid tumors

Autor: Richard S. Ungerleider, Elisabeth I. Heath, Amy Weise, Ulka N. Vaishampayan, Yasuo Urata, Dailan Danforth

Publikováno v: Investigational New Drugs. 40:300-307

Background Dysregulation of histone deacetylases (HDACs) is common in cancer and is critical to the development and progression of the majority of tumors. This first-in-human Phase Ia study assessed the safety, efficacy, and pharmacokinetics (PK) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44631b32dcccb6bc10b1631713c7e829
https://doi.org/10.1007/s10637-021-01180-9

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