Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Daiki Masukawa"'
Autor:
Hiraku Uchimura, Kaori Kanai, Masami Arai, Miyu Inoue, Akitoyo Hishimoto, Daiki Masukawa, Yoshio Goshima
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 3, Pp 178-181 (2023)
Methylphenidate (MPH) and methamphetamine (METH) are the current treatments of choice for attention deficit/hyperactivity disorder. We previously reported that METH induces the release of dopamine (DA) and of the neurotransmitter candidate L-3,4-dihy
Externí odkaz:
https://doaj.org/article/bf13d8cb1e454bee9ed6ece9b6aa3f36
Autor:
Masayuki Nakano, Motokazu Koga, Tatsuo Hashimoto, Natsuki Matsushita, Daiki Masukawa, Yusuke Mizuno, Hiraku Uchimura, Ryo Niikura, Tomoyuki Miyazaki, Fumio Nakamura, Suo Zou, Takahiro Shimizu, Motoaki Saito, Kouichi Tamura, Takahisa Goto, Yoshio Goshima
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 2, Pp 214-220 (2022)
Pulmonary hypertension (PH) is a severe and progressive disease that causes elevated right ventricular systolic pressure, right ventricular hypertrophy and ultimately right heart failure. However, the underlying pathophysiologic mechanisms are poorly
Externí odkaz:
https://doaj.org/article/0731879c0abe4c7cb92a39d3bebe47cb
Autor:
Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Junichi Sakaguchi, Yoko Ikoma, Yoshimune Sameshima, Yuki Kambe, Akihiro Yamanaka, Tomoyuki Kuwaki
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 4, Pp 881-886 (2022)
In the central nervous system, the A6 noradrenaline (NA) and the B3 serotonin (5-HT) cell groups are well-recognized players in the descending antinociceptive system, while other NA/5-HT cell groups are not well characterized. A5/A7 NA and B2 5-HT ce
Externí odkaz:
https://doaj.org/article/9c1a7e1ecb2e4f21a23d69274957f67f
Autor:
Shunpei Moriya, Hitoshi Takahashi, Daiki Masukawa, Makiko Yamada, Jun Ishigooka, Katsuji Nishimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 2, Pp 198-201 (2021)
The orexinergic system plays a significant role in regulating proper sleep/wake maintenance. Dual orexin receptor antagonist (DORA) is widely prescribed for insomnia symptoms. The antagonist acts on orexin 1 and 2 receptors located in certain brain a
Externí odkaz:
https://doaj.org/article/d78a913b54154781a34bd7ae7f18714b
Autor:
Daiki Masukawa, Daisuke Nishizawa, Kaori Kanai, Satoshi Kitamura, Yuka Kasahara, Tatsuo Hashimoto, Ryo Takahagi, Junko Hasegawa, Kyoko Nakayama, Naomi Sato, Fumihiko Tanioka, Haruhiko Sugimura, Kazutaka Ikeda, Yoshio Goshima
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 2, Pp 89-93 (2020)
l-3,4-dihydroxyphenylalanine (l-DOPA) is a candidate neurotransmitter. l-DOPA is released by nicotine through nicotinic receptors. Recently, G-protein coupled receptor GPR143, was identified as a receptor for l-DOPA. In this study, genetic associatio
Externí odkaz:
https://doaj.org/article/9fc2bc4cfa004a55ab0bbada4d5a0d21
Autor:
Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Honami Setoyama, Yunsu Hwang, Akihiro Yamanaka, Tomoyuki Kuwaki
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract The roles of serotonergic and noradrenergic signaling in nociceptive processing in the central nervous system are well known. However, dopaminergic signaling is also relevant to various physical functions, including nociception. The zona inc
Externí odkaz:
https://doaj.org/article/a1a7f8b7b81f49029b41bdd3fa8c7725
Autor:
Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Yuki Kambe, Junichi Sakaguchi, Honami Setoyama, Akihiro Yamanaka, Tomoyuki Kuwaki
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Nociception is important perception that has harmful influence on daily life of humans. As to main pain management system, some descending pathways are called descending antinociceptive systems (DAS). As main pathways of DAS, it is well know
Externí odkaz:
https://doaj.org/article/de4e0838fea04c0a91397d5bc74e59b7
Publikováno v:
Journal of Pharmacological Sciences, Vol 141, Iss 1, Pp 41-48 (2019)
Neurite outgrowth is a complex differentiation process regulated by external and/or internal mechanisms. Among external mechanisms, G-protein coupled receptors (GPCRs) have been implicated in this process, but the pathways involved are not fully unde
Externí odkaz:
https://doaj.org/article/33a5e71a3538430daa71d80be5cfd89f
Autor:
Shunpei Moriya, Hitoshi Takahashi, Daiki Masukawa, Makiko Yamada, Jun Ishigooka, Katsuji Nishimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 1, Pp 57-59 (2020)
Some psychiatric diseases are associated with disruptions in the circadian clock system. Ziprasidone (ZIP), a second-generation antipsychotic, is widely used for psychiatry-related pharmacotherapy but its mechanism has not been clearly elucidated. We
Externí odkaz:
https://doaj.org/article/1cefc9863f0642c5a85c2f8f24146284
Autor:
Keiichi Yazawa, Fumio Nakamura, Daiki Masukawa, Sho Sato, Yukihiko Hiroshima, Yasuhiro Yabushita, Ryutaro Mori, Ryusei Matsuyama, Ikuma Kato, Hideki Taniguchi, Yoshio Goshima, Itaru Endo
Publikováno v:
Translational Oncology, Vol 13, Iss 3, Pp - (2020)
Pancreatic intraepithelial neoplasia (PanIN), the most common premalignant lesion of the pancreas, is a histologically well-defined precursor to invasive pancreatic ductal adenocarcinoma (PDAC). However, the molecular mechanisms underlying the progre
Externí odkaz:
https://doaj.org/article/0e1ffe5d2cd1447d8abdf173a9c71bca