Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Daiju Tsuchiya"'
Autor:
Masatoshi Inden, Takahiro Taira, Yoshihisa Kitamura, Takashi Yanagida, Daiju Tsuchiya, Kazuyuki Takata, Daijiro Yanagisawa, Kaneyasu Nishimura, Takashi Taniguchi, Yoshiaki Kiso, Kanji Yoshimoto, Tomohiro Agatsuma, Shizuyo Koide-Yoshida, Sanae M.M. Iguchi-Ariga, Shun Shimohama, Hiroyoshi Ariga
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 144-158 (2006)
DJ-1 has recently been shown to be responsible for onset of familial Parkinson’s disease (PD), PARK7. DJ-1 has been shown to play roles in transcriptional regulation and anti-oxidative stress, and loss of its function is thought to trigger onset of
Externí odkaz:
https://doaj.org/article/d682fd55d046410e8c9d64fd45de4687
Autor:
Daiju Tsuchiya, Yoshihisa Kitamura, Kazuyuki Takata, Takashi Taniguchi, Kengo Uemura, Hiroaki Miki, Tadaomi Takenawa, Shun Shimohama
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 3, Pp 354-358 (2006)
Presenilin 1 (PS1) is a multifunctional protein, and its mutations are highly related to familial Alzheimer’s disease (AD). In this study, we examined the effects of PS1 overexpression on neuronal morphology using SH-SY5Y cells. Overexpression of d
Externí odkaz:
https://doaj.org/article/d864c7f69f124a9e9bafc27d90d99f6f
Autor:
Yoshihisa Kitamura, Daijiro Yanagisawa, Masatoshi Inden, Kazuyuki Takata, Daiju Tsuchiya, Toshiyuki Kawasaki, Takashi Taniguchi, Shun Shimohama
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 2, Pp 289-293 (2005)
The function of microglia in the brain parenchyma is not fully understood. Occlusion of the middle cerebral artery (MCA) and reperfusion caused behavioral dysfunction with massive neuronal loss in the rat cerebral cortex and striatum. When exogenous
Externí odkaz:
https://doaj.org/article/17acb7e0dc994f9b9fc91d3e7ad571d6
Autor:
Yoshihisa Kitamura, Kazuyuki Takata, Masatoshi Inden, Daiju Tsuchiya, Daijiro Yanagisawa, Junko Nakata, Takashi Taniguchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 2, Pp 203-206 (2004)
Microglia are macrophage-like phagocytic cells in the brain parenchyma. However, microglial function after neurodegeneration is not fully understood. In this study, occlusion of the middle cerebral artery (MCA) and reperfusion caused massive neuronal
Externí odkaz:
https://doaj.org/article/3930895d7fc44d31a4f86baf0e629af7
Autor:
Masatoshi Inden, Dohoon Kim, Yuanjin Gu, Yoshihisa Kitamura, Jun-ichi Kondo, Daiju Tsuchiya, Takashi Taniguchi, Shun Shimohama, Akinori Akaike, Shoichiro Sumi, Kazutomo Inoue
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 1, Pp 53-64 (2004)
Embryonic stem (ES) cells have many of the characteristics of an optimal cell source for cell-replacement therapy. Although the usefulness of the in vitro generation of dopamine (DA)-neural precursors from ES cells has been widely discussed, function
Externí odkaz:
https://doaj.org/article/1965c6f15ed049679c6154dcd79f0a23
Autor:
Yoshihisa Kitamura, Atsushi Miyamura, Kazuyuki Takata, Masatoshi Inden, Daiju Tsuchiya, Kumi Nakamura, Takashi Taniguchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 228-236 (2003)
Recently, it has been shown that endoplasmic reticulum (ER) stress causes apoptosis. However, the mechanism of the ER stress-dependent pathway is not fully understood. In human neuroblastoma SH-SY5Y cells, we detected a caspase-12-like protein that h
Externí odkaz:
https://doaj.org/article/12de6b2b2f50462087604c10c3731648
Autor:
Yoshihisa Kitamura, Keiichi Shibagaki, Kazuyuki Takata, Daiju Tsuchiya, Takashi Taniguchi, Peter J. Gebicke-Haerter, Hiroaki Miki, Tadaomi Takenawa, Shun Shimohama
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 2, Pp 115-123 (2003)
Alzheimer’s disease (AD) is characterized by the accumulation of extracellular amyloid-β (Aβ) fibrils with microglia. Recently, there has been great interest in the microglial phagocytosis of Aβ, because the microglial pathway is considered to b
Externí odkaz:
https://doaj.org/article/d71193bdf1de434b9487bcc5f1d4da3d
Autor:
Kazuyuki Takata, Yoshihisa Kitamura, Masaaki Umeki, Daiju Tsuchiya, Jun-ichi Kakimura, Takashi Taniguchi, Peter J. Gebicke-Haerter, Shun Shimohama
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 4, Pp 330-333 (2003)
In Alzheimer’s disease, fibrillar amyloid-β (Aβ) peptides form senile plaques associated with microglia. However, the relationship between Aβ peptides and microglia is not fully understood. In this study, the incubation of Aβ1-40 (Aβ40) produc
Externí odkaz:
https://doaj.org/article/1ff8472ac39a457aa10d2b06f551ca4e
Autor:
Masahiro Yamada, Takayuki Arakawa, Jun Kamishikiryou, Aki Morihiro, Yasuhiro Tanida, Hiroshi Onoue, Naotaka Son, Kouji Tokumo, Hiroaki Nishio, Eijiro Kojima, Hiroshi Kazuno, Masahiro Okada, Daiju Tsuchiya, Narumi Sugihara, Itsuko Yokota, Tetsurou Tanaka
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 42:113-121
Autor:
Mutsumi Miyauchi, Masatoshi Ohnishi, Atsuko Inoue, Takashi Takata, Chiharu Fukutomi, Hiroaki Nishio, Daiju Tsuchiya, Miho Kanoh
Publikováno v:
Journal of Molecular Neuroscience. 48:541-549
The neurotrophic effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on rat sensory neuronal cell line ND7/23 cells were investigated. PACAP caused a concentration-dependent increase in the number of neurite-bearing cells and the ex