Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Daifeng Wang"'
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103375- (2024)
Summary: Here, we present a protocol for using Brain and Organoid Manifold Alignment (BOMA), a cloud-based web app for comparative gene expression data analysis between brains and organoids. We describe steps for performing a global alignment of deve
Externí odkaz:
https://doaj.org/article/54ef7c1284d8427c8f08ec728517462b
Autor:
Pramod Bharadwaj Chandrashekar, Sayali Alatkar, Jiebiao Wang, Gabriel E. Hoffman, Chenfeng He, Ting Jin, Saniya Khullar, Jaroslav Bendl, John F. Fullard, Panos Roussos, Daifeng Wang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive. With emerging multimodal data for these mechanisms,
Externí odkaz:
https://doaj.org/article/c8c7e6c0ecce42439e257b1b9cc4a68e
Autor:
Sayali Anil Alatkar, Daifeng Wang
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Multimodal measurements of single-cell sequencing technologies facilitate a comprehensive understanding of specific cellular and molecular mechanisms. However, simultaneous profiling of multiple modalities of single cells is challenging, and
Externí odkaz:
https://doaj.org/article/982ba05195f44ce88bd1e1bec256abfd
Autor:
Yu Guo, Minjie Shen, Qiping Dong, Natasha M. Méndez-Albelo, Sabrina X. Huang, Carissa L. Sirois, Jonathan Le, Meng Li, Ezra D. Jarzembowski, Keegan A. Schoeller, Michael E. Stockton, Vanessa L. Horner, André M. M. Sousa, Yu Gao, Birth Defects Research Laboratory, Jon E. Levine, Daifeng Wang, Qiang Chang, Xinyu Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the brain. The contribution of these targets to fragile X syndrome (FXS) and related autism spectrum disorder (ASD) remains unclear. Here, we show that FMRP de
Externí odkaz:
https://doaj.org/article/c712033063bc4873a8e01bd8ebf89faa
Publikováno v:
Patterns, Vol 4, Iss 11, Pp 100847- (2023)
Summary: Single-cell techniques like Patch-seq have enabled the acquisition of multimodal data from individual neuronal cells, offering systematic insights into neuronal functions. However, these data can be heterogeneous and noisy. To address this,
Externí odkaz:
https://doaj.org/article/f5b37037b82748f58aba5215da906ada
Autor:
Shuang Liu, Hyejung Won, Declan Clarke, Nana Matoba, Saniya Khullar, Yudi Mu, Daifeng Wang, Mark Gerstein
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Neuropsychiatric disorders afflict a large portion of the global population and constitute a significant source of disability worldwide. Although Genome-wide Association Studies (GWAS) have identified many disorder-associated vari
Externí odkaz:
https://doaj.org/article/f27667976e18464f80dc9bd617221320
Autor:
Daifeng Wang, John R. Pruett
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0d85ef18eb1242b880916ee74d7fee1a
Autor:
Chirag Gupta, Pramod Chandrashekar, Ting Jin, Chenfeng He, Saniya Khullar, Qiang Chang, Daifeng Wang
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-22 (2022)
Abstract Intellectual and Developmental Disabilities (IDDs), such as Down syndrome, Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth or early childhood. IDDs are characterized by significant impairment in int
Externí odkaz:
https://doaj.org/article/a1166f7da22f46679a4d499170c6bf81
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Fragile X syndrome (FXS), the most prevalent inherited intellectual disability and one of the most common monogenic forms of autism, is caused by a loss of fragile X messenger ribonucleoprotein 1 (FMR1). We have previously shown t
Externí odkaz:
https://doaj.org/article/49cda3c0fde74245aada0c716efb5fbd
Publikováno v:
Robotics, Vol 12, Iss 6, p 153 (2023)
In this work, the motion control of a robotic wheelchair to achieve safe and intelligent movement in an unknown scenario is proposed. The primary objective is to develop a comprehensive framework for a robotic wheelchair that combines a global path p
Externí odkaz:
https://doaj.org/article/6538e7ef953745b3b4ac098ae7c57a85