Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daicia C. Allen"'
Autor:
Vanessa A. Jimenez, Daicia C. Allen, Verginia C. Cuzon Carlson, Kathleen A. Grant, Nicole A.R. Walter, Timothy L. Carlson
Publikováno v:
Neuropsychopharmacology
Circuit manipulation has been a staple technique in neuroscience to identify how the brain functions to control complex behaviors. Chemogenetics, including designer receptors exclusively activated by designer drugs (DREADDs), have proven to be a powe
Autor:
Kathleen A. Grant, Daicia C. Allen
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Animal models are an essential feature of drug and pharmacotherapy development for treating alcohol use disorders (AUDs). The rhesus macaque is a robust animal model for many aspects of AUDs particularly in exploiting individual differenc
Autor:
Daicia C. Allen, Yan Xiong, Timothy L. Carlson, Verginia C. Cuzon Carlson, Jian Jin, Kathleen A. Grant
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 368:199-207
Translating chemogenetic techniques from nonhuman primates to potential clinical applications has been complicated in part due to in vivo conversion of the chemogenetic actuator, clozapine N-oxide (CNO), to its pharmacologically active parent compoun
Autor:
Jung H. Tak, Eduardo Alvarez, Michael D. Nunez, Daicia C. Allen, Elizabeth J. Jun, Michele A. Basso, Alex R. Bautista
Publikováno v:
Nature neuroscience
Trained monkeys performed a two-choice perceptual decision-making task in which they reported the perceived orientation of a dynamic Glass pattern, before and after unilateral, reversible, inactivation of a brainstem area—the superior colliculus (S
Publikováno v:
Psychopharmacology. 234:1881-1889
Hypothalamic-pituitary-adrenal (HPA) axis activity under different social settings in non-human primates is understudied.The aim of this study is to evaluate the response of pituitary-adrenal hormones (adrenocorticotropic hormone (ACTH) and cortisol)
Autor:
Daicia C, Allen, Timothy L, Carlson, Yan, Xiong, Jian, Jin, Kathleen A, Grant, Verginia C, Cuzon Carlson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 368(2)
Translating chemogenetic techniques from nonhuman primates to potential clinical applications has been complicated in part due to in vivo conversion of the chemogenetic actuator, clozapine N-oxide (CNO), to its pharmacologically active parent compoun
Autor:
Matthew M. Ford, Alexander Kuryatov, Kathleen A. Grant, Eliot R. Spindel, Jon Lindstrom, Daicia C. Allen, Lyndsey E. Shorey-Kendrick, Larry J. Wilhelm
Publikováno v:
Neuropharmacology
Nicotinic acetylcholine receptors (nAChRs) are highly conserved between humans and non-human primates. Conservation exists at the level of genomic structure, protein structure and epigenetics. Overall homology of nAChRs at the protein level is 98% in
Publikováno v:
The Behavioral Neuroscience of Drug Discrimination ISBN: 9783319985596
The progress on understanding the pharmacological basis of ethanol’s discriminative stimulus effects has been substantial, but appears to have plateaued in the past decade. Further, the cross-species translational efforts are clear in laboratory an
Autor:
Tatiana A. Shnitko, Kathleen A. Grant, Steven W. Gonzales, Daicia C. Allen, Nicole A.R. Walter
Publikováno v:
Frontiers in Behavioral Neuroscience
Attentional set-shifting ability is an executive function underling cognitive flexibility in humans and animals. In humans, this function is typically observed during a single experimental session where dimensions of playing cards are used to measure
Autor:
Allison R. Coker, Daicia C. Allen, Elyssa B. Margolis, Jennifer M. Mitchell, Howard L. Fields
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:195-203
Background While there is a growing body of evidence that the delta opioid receptor (DOR) modulates ethanol (EtOH) consumption, development of DOR-based medications is limited in part because there are 2 pharmacologically distinct DOR subtypes (DOR-1