Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Daici Chen"'
Autor:
Wanjun Liu, Si Chen, Wenqing Xie, Qian Wang, Qianxin Luo, Minghan Huang, Minyi Gu, Ping Lan, Daici Chen
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-22 (2023)
Abstract Background The mitochondrial gene MCCC2, a subunit of the heterodimer of 3-methylcrotonyl-CoA carboxylase, plays a pivotal role in catabolism of leucine and isovaleric acid. The molecular mechanisms and prognostic value still need to be expl
Externí odkaz:
https://doaj.org/article/0108fa6b2c40421fba94feab2fbffa17
Autor:
Zixu Yuan, Xihu Yu, Wenle Chen, Daici Chen, Jian Cai, Yingming Jiang, Xiaoxia Liu, Zhijie Wu, Lei Wang, William M. Grady, Hui Wang
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The screening biomarkers for early detection of colorectal cancer (CRC) is lacking. The aim is to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC. We conducted integrative analyses of epige
Externí odkaz:
https://doaj.org/article/2616435b98904b0ebbc866de67484ed4
Autor:
Wuguo Li, Wei Chen, Jialin Wang, Guangyin Zhao, Lianzhou Chen, Yong Wan, Qianxin Luo, Wenwen Li, Haoji Huang, Wenying Li, Wu Li, Yutong Yang, Daici Chen, Qiao Su
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12518- (2022)
Patient-derived xenograft (PDX) models are more faithful in maintaining the characteristics of human tumors than cell lines and are widely used in drug development, although they have some disadvantages, including their relative low success rate, lon
Externí odkaz:
https://doaj.org/article/34f56be0ed084300863e772e5c118bec
Autor:
Shaoyong Peng, Daici Chen, Jian Cai, Zixu Yuan, Binjie Huang, Yichen Li, Huaiming Wang, Qianxin Luo, Yingyi Kuang, Wenfeng Liang, Zhihang Liu, Qian Wang, Yanmei Cui, Hui Wang, Xiaoxia Liu
Publikováno v:
Molecular Oncology, Vol 15, Iss 5, Pp 1391-1411 (2021)
Most cancer‐related deaths result from the progressive growth of metastases. Patients with peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is still unclear why colorectal cancer (CRC) cells home to and prol
Externí odkaz:
https://doaj.org/article/36472c26909a4c7886ec898c00be9bf6
Autor:
Yanjiong He, Zuolin Zhou, Xiaoyan Huang, Qi Guan, Qiyuan Qin, Miaomiao Zhu, Huaiming Wang, Qinghua Zhong, Daici Chen, Hui Wang, Lekun Fang, Tenghui Ma
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundChronic radiation proctopathy (CRP) is a common complication after radiation therapy for pelvic malignancies. Compared with diversion surgery, resection surgery removes the damaged tissue completely to avoid the risks of recurrence and impr
Externí odkaz:
https://doaj.org/article/3aab6f00ac8f47da871defdb9f697fd0
Autor:
Qian Wang, Wanjun Liu, Si Chen, Qianxin Luo, Yichen Li, Shaoyong Peng, Huaiming Wang, Xiaoxia Liu, Daici Chen
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101171- (2021)
Background: The ORMDL1 gene is known as a crucial negative regulator of sphingolipid biogenesis. However, the ORMDL1 gene has rarely been studied in a tumor-related context. Therefore, its prognostic value and functional significance in colorectal ca
Externí odkaz:
https://doaj.org/article/f011092bce504fe6876757cef69a3b4b
Autor:
Yitao Zhang, Jiaojie Xue, Ling Zhou, Jinhong Si, Shiyao Cheng, Kanglin Cheng, Shuqi Yu, Mao Ouyang, Zhichong Chen, Daici Chen, Weijie Zeng
Publikováno v:
EClinicalMedicine, Vol 40, Iss , Pp 101128- (2021)
Background: The incidence of cardiovascular events in perioperative period of gastrointestinal tumor surgery cannot be ignored, and studies have shown that level of postoperative troponin is related to the postoperative risk of non-cardiac surgery. H
Externí odkaz:
https://doaj.org/article/2df1f74545f54a04848ebd56ffd92f22
Autor:
Zixu Yuan, Xihu Yu, Wenle Chen, Daici Chen, Jian Cai, Yingming Jiang, Xiaoxia Liu, Zhijie Wu, Lei Wang, William M. Grady, Hui Wang
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c03a9c4042f14fc483e948b7b72388eb
Publikováno v:
Translational Oncology, Vol 13, Iss 12, Pp 100874- (2020)
Study rationale: The coexistence of KRAS and PIK3CA mutations in cells implies potential synergistic hyperactivation of the Ras/MAPK and PI3K/Akt oncogenic pathways. Therefore, it is desirable to investigate the concomitant mutations of KRAS and PIK3
Externí odkaz:
https://doaj.org/article/c829a71d95c1465d9f03c07b8901e252
Autor:
Yanmei Cui, Haiyong Wu, Zhihang Liu, Tenghui Ma, Wenfeng Liang, Qingzhi Zeng, Daici Chen, Qiyuan Qin, Binjie Huang, Michael Hu Wang, Xiaoyan Huang, Yanjiong He, Yingyi Kuang, Shinya Sugimoto, Toshiro Sato, Lei Wang
Publikováno v:
The Journal of Pathology. 259:180-193
Radiation enteritis (RE) is a prevalent complication of radiotherapy for pelvic malignant tumors, characterized by severe intestinal epithelial destruction and progressive submucosal fibrosis. However, little is known about the pathogenesis of this d