Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Daichi Yokoi"'
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Various wearable devices for objectively evaluating motor symptoms of patients with Parkinson’s disease (PD) have been developed. Importantly, previous studies have suggested protective effects of physical activity in PD. Howeve
Externí odkaz:
https://doaj.org/article/64cf261dbe3840c3a2ef6627a52ff3b5
Publikováno v:
Journal of the Neurological Sciences. 405:39-42
Publikováno v:
BMC Neurology
BMC Neurology, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Neurology, Vol 20, Iss 1, Pp 1-10 (2020)
Background Various wearable devices for objectively evaluating motor symptoms of patients with Parkinson’s disease (PD) have been developed. Importantly, previous studies have suggested protective effects of physical activity in PD. However, the re
Autor:
Osamu Onodera, Akira Taniguchi, Gen Sobue, Yuishin Izumi, Osamu Kano, Satoshi Kuwabara, Naoki Suzuki, Nobutaka Hattori, Koichi Okamoto, Kazuaki Kanai, Ikuko Aiba, Masao Nagasaki, Ryuji Kaji, Ryoichi Nakamura, Kouichi Mizoguchi, Masashi Aoki, Yoichiro Kamatani, Yasuyuki Ohta, Kazuharu Misawa, Yukihide Momozawa, Masahiro Nakatochi, Kazuko Hasegawa, Rina Hashimoto, Kenji Nakashima, Koji Abe, Hazuki Watanabe, Naoki Atsuta, Hirohisa Watanabe, Daichi Yokoi, Tomohiko Ishihara, Michiaki Kubo, Mitsuya Morita, Shiro Ikegawa, Kazumoto Shibuya, Naoko Minegishi, Sho Furuhashi, Yohei Okada, Noriko Ishida, Masahisa Katsuno, Toru Yamashita, Naoki Hayashi, Genki Tohnai, Masaya Oda
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Amyotrophic lateral sclerosis (ALS) is a devastating progressive motor neuron disease that affects people of all ethnicities. Approximately 90% of ALS cases are sporadic and thought to have multifactorial pathogenesis. To understand the genetics of s
Autor:
Hisashi Okada, Kazuo Mano, Kazuhiro Hara, Yoji Goto, Jun Sone, Yohei Iguchi, Takashi Ando, Ayuka Murakami, Yumiko Harada, Tomoo Ogi, Haruki Koike, Masashi Suzuki, Satoshi Okuda, Seiya Noda, Seigo Kimura, Gen Sobue, Naoki Atsuta, Daichi Yokoi, Makoto Hattori, Ichizo Nishino, Ryoichi Nakamura, Yusuke Yoshida, Tomohiko Nakamura, Satoshi Kuru, Masahisa Katsuno
Publikováno v:
Neurobiology of aging. 100
Mutations in the valosin-containing protein (VCP) gene are known to cause various neurodegenerative disorders. Here, we report 8 Japanese patients [6 men, 2 women; median age at onset: 49.5 (range, 35–58) years] from 5 unrelated families with VCP m
Autor:
Naoki Atsuta, Daichi Yokoi, Hirohisa Watanabe, Shinji Naganawa, Masahisa Katsuno, Hazuki Watanabe, Yuichi Riku, Michihito Masuda, Joe Senda, Mizuki Ito, Epifanio Bagarinao, Ryoichi Nakamura, Kazunori Imai, Gen Sobue
Publikováno v:
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 88(11):901-907
Purpose Amyotrophic lateral sclerosis (ALS) presents with varying degrees of brain degeneration that can extend beyond the corticospinal tract (CST). Furthermore, the clinical course and progression of ALS varies widely. Brain degeneration detected u
Autor:
Masaya Oda, Kazuaki Kanai, Kazumoto Shibuya, Naoki Atsuta, Ryuji Kaji, Satoshi Kuwabara, Mitsuya Morita, Naoki Suzuki, Ikuko Aiba, Nobutaka Hattori, Masahisa Katsuno, Kouichi Mizoguchi, Daichi Yokoi, Akira Taniguchi, Gen Sobue, Osamu Kano, Naoki Hayashi, Masahiro Nakatochi, Ryoichi Nakamura, Masashi Aoki, Yuishin Izumi
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry. 91(3)
ObjectiveThe aim of this study is to describe and clarify the factors affecting the prognosis of Japanese patients with amyotrophic lateral sclerosis (ALS) undergoing tracheostomy invasive ventilation (TIV) therapy.MethodsWe conducted a prospective l
Autor:
Yuishin Izumi, Koichi Okamoto, Ikuko Aiba, Naoki Atsuta, Mitsuya Morita, Koji Abe, Masahiro Nakatochi, Masaya Oda, Ryuji Kaji, Satoshi Kuwabara, Naoki Hayashi, Akira Taniguchi, Daichi Yokoi, Hirohisa Watanabe, Masahisa Katsuno, Gen Sobue, Kenji Nakashima, Kouichi Mizoguchi, Osamu Kano, Kazuaki Kanai, Nobutaka Hattori, Hazuki Watanabe, Genki Tohnai, Ryoichi Nakamura, Masashi Aoki
Publikováno v:
Neurobiology of Aging. 97:147.e11-147.e17
Two recent genetic studies reported that loss-of-function mutation of the C-terminal cargo-binding tail domain of the KIF5A gene cause amyotrophic lateral sclerosis (ALS). The aim of this study is to investigate the frequency of KIF5A variants in Jap
Autor:
Koji Abe, Koichi Mizoguchi, Satoshi Kuwabara, Ryoichi Nakamura, Masashi Aoki, Masaya Oda, Masahisa Katsuno, Daichi Yokoi, Takashi Imai, Ryuji Kaji, Yuishin Izumi, Mizuki Ito, Kazuaki Kanai, Shiro Ikegawa, Michiaki Kubo, Akihiro Hirakawa, Aritoshi Iida, Koichi Okamoto, Ikuko Aiba, Shinsuke Ishigaki, Kenji Nakashima, Shoji Tsuji, Naoki Atsuta, Mitsuya Morita, Masahiro Nakatochi, Kazuko Hasegawa, Hazuki Watanabe, Akihiro Kawata, Akira Taniguchi, Gen Sobue, Osamu Kano, Hirohisa Watanabe
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 87:851-858
Objective To classify the patterns of functional decline in patients with sporadic amyotrophic lateral sclerosis (ALS) and explore the genetic backgrounds that modified these patterns. Methods We included 465 patients with sporadic ALS in the analysi
Autor:
Kaori Kawai, Naoki Atsuta, Mitsuya Morita, Akihiro Hirakawa, Ryoichi Nakamura, Masahisa Katsuno, Yasuhiro Maeda, Akira Taniguchi, Kazunori Kimura, Gen Sobue, Yuji Hotta, Daichi Yokoi, Kensuke Ikenaka, Kouichi Mizoguchi, Hideki Mochizuki
Publikováno v:
Neurology. 92(16)
ObjectiveTo investigate whether arginine methylation is altered in patients with amyotrophic lateral sclerosis (ALS) and how it affects disease severity, progression, and prognosis.MethodsWe compared the immunoreactivity of protein arginine methyltra