Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daichi Onozato"'
Autor:
Anna Nakanishi, Satoshi Toyama, Daichi Onozato, Chihiro Watanabe, Tadahiro Hashita, Takahiro Iwao, Tamihide Matsunaga
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 351-361 (2022)
Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by repeated remissions and relapses. Immunosuppressive drugs have facilitated the induction and maintenance of remission in many patients with UC. However, immunosup
Externí odkaz:
https://doaj.org/article/fc4615f9a90e47e0b02a5bd0a10d9f3c
Autor:
Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Tadahiro Hashita, Hiroshi Takase, Teruaki Sugino, Rei Unno, Kazumi Taguchi, Shuzo Hamamoto, Ryosuke Ando, Kentaro Mizuno, Keiichi Tozawa, Tamihide Matsunaga, Kenjiro Kohri, Takahiro Yasui
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-12 (2019)
Background: We previously discovered that renal macrophages (Mφs) phagocytose renal calcium oxalate monohydrate (COM) crystals. This study investigated the processing of engulfed crystals using in vitro models. Methods: J774.1 mouse Mφs were expose
Externí odkaz:
https://doaj.org/article/6ada40212bbf4039bfbdc2e5015a900d
Autor:
Isamu Ogawa, Daichi Onozato, Shiho Anno, Hisato Hayashi, Tatsuro Kanaki, Takahiro Iwao, Tamihide Matsunaga
Publikováno v:
Biomaterials. 288:121696
Currently, there are many challenges in the culture of human induced pluripotent stem (iPS) cell-derived intestinal organoids (HIOs) for use in drug discovery, disease research, and regenerative medicine. For example, the main culture method, embeddi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768d191100967897e6a52e1fd37fc703
https://doi.org/10.1016/j.biomaterials.2022.121696
https://doi.org/10.1016/j.biomaterials.2022.121696
Autor:
Takahiro Yasui, Keiichi Tozawa, Hiroshi Takase, Tadahiro Hashita, Hiromasa Aoki, Kazumi Taguchi, Shuzo Hamamoto, Ryosuke Ando, Teruaki Sugino, Rei Unno, Taiki Kato, Kenjiro Kohri, Atsushi Okada, Kentaro Mizuno, Daichi Onozato, Tamihide Matsunaga
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-12 (2019)
Background: We previously discovered that renal macrophages (Mφs) phagocytose renal calcium oxalate monohydrate (COM) crystals. This study investigated the processing of engulfed crystals using in vitro models. Methods: J774.1 mouse Mφs were expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fb850b97c0f8593fe16968d3880d0e
https://doi.org/10.1159/000501965
https://doi.org/10.1159/000501965
Autor:
Yuriko Kida, Shota Mizuno, Tadahiro Hashita, Isamu Ogawa, Takahiro Iwao, Daichi Onozato, Tamihide Matsunaga
Publikováno v:
Journal of pharmaceutical sciences. 110(7)
Human induced pluripotent stem (iPS) cell-derived intestinal organoids have low invasiveness; however, the current differentiation method does not reflect the crypt-villus-like structure due to structural immaturity. Here, we generated budding-like o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b961e8ff3bf15a2e1c6b4f2baf9eece2
https://pubmed.ncbi.nlm.nih.gov/33794275
https://pubmed.ncbi.nlm.nih.gov/33794275
Autor:
Takahiro Iwao, Isamu Ogawa, Daichi Onozato, Tamihide Matsunaga, Tadahiro Hashita, Takumi Akagawa, Yuriko Kida
Publikováno v:
Biologicalpharmaceutical bulletin. 43(7)
Inflammatory bowel disease, which typically manifests as Crohn's disease and ulcerative colitis, is caused by the abnormal production of cytokines such as tumor necrosis factor (TNF)-α and transforming growth factor (TGF)-β. These cytokines damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b6a1a03c72a71ae469b0246a7ae9d1
https://pubmed.ncbi.nlm.nih.gov/32612071
https://pubmed.ncbi.nlm.nih.gov/32612071
Autor:
Taiki Kato, Rika Banno, Shigeru Ohshima, Tadahiro Hashita, Hiromasa Aoki, Hiroshi Takase, Atsushi Okada, Kazumi Taguchi, Kenjiro Kohri, Takahiro Yasui, Daichi Onozato, Tamihide Matsunaga
Publikováno v:
Journal of Urology. 203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98facdb6007a84160250773f5d9ea5e0
https://doi.org/10.1097/ju.0000000000000824.011
https://doi.org/10.1097/ju.0000000000000824.011
Autor:
Misaki Yamashita, Takahiro Iwao, Daichi Onozato, Takumi Akagawa, Tamihide Matsunaga, Yuriko Kida, Anna Nakanishi, Isamu Ogawa, Tadahiro Hashita
Publikováno v:
Drug Metabolism and Disposition. 46:1572-1580
Intestinal organoids morphologically resemble intestinal tissues and are expected to be used in both regenerative medicine and drug development studies, including pharmacokinetic studies. However, the pharmacokinetic properties of these organoids rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608afed76795b140796b732c0d338b7a
https://doi.org/10.1124/dmd.118.080374
https://doi.org/10.1124/dmd.118.080374
Autor:
Kazumi Taguchi, Daichi Onozato, Tamihide Matsunaga, Kenjiro Kohri, Tadahiro Hashita, Hiromasa Aoki, Takahiro Yasui, Hiroshi Takase, Taiki Kato, Atsushi Okada
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:We have demonstrated the control of urinary stone formation using macrophages (Mφ) in basic research. The purpose of this study is to establish a method for analysis of ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ee45b5756adcc1dcadb249dcfa491f
https://doi.org/10.1097/01.ju.0000556379.32384.98
https://doi.org/10.1097/01.ju.0000556379.32384.98
Autor:
Ryosuke Fukuyama, Tadahiro Hashita, Takahiro Iwao, Misaki Yamashita, Takumi Akagawa, Yuriko Kida, Akiko Koeda, Daichi Onozato, Tamihide Matsunaga
Publikováno v:
Stem cells and development. 27(15)
In preclinical studies, the cynomolgus monkey (CM) model is frequently used to predict the pharmacokinetics of drugs in the human small intestine, because of its evolutionary closeness to humans. Intestinal organoids that mimic the intestinal tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04e1007c36acf58ee3726627fc37f70
https://pubmed.ncbi.nlm.nih.gov/29742964
https://pubmed.ncbi.nlm.nih.gov/29742964