Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daichi, Sadatomi"'
Autor:
Peilin Li, Yusuke Inoue, Daisuke Miyamoto, Toshiyuki Adachi, Satomi Okada, Tomohiko Adachi, Akihiko Soyama, Masaaki Hidaka, Kengo Kanetaka, Shinichiro Ito, Daichi Sadatomi, Sachiko Mogami, Naoki Fujitsuka, Weili Gu, Susumu Eguchi
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283626 (2023)
BackgroundDaikenchuto (DKT) has positive therapeutic effects on improving various gastrointestinal disorders. The present study investigated whether or not DKT has a potential therapeutic effect on chemotherapy-induced acute small intestinal mucositi
Externí odkaz:
https://doaj.org/article/56de2469e52044a49bd7fff4df3734d2
Autor:
Kunitsugu Kubota, Yumi Harada, Hitomi Sekine, Naoki Fujitsuka, Seiichi Iizuka, Daichi Sadatomi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111860-(2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Autor:
Taro, Oshiro, Yumi, Harada, Kunitsugu, Kubota, Daichi, Sadatomi, Hitomi, Sekine, Mitsue, Nishiyama, Naoki, Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy. 152:113263
Changes in the intestinal microbiota are known to occur in constipated patients. Dietary fiber restriction presents obstacles to appropriate defecation and affects fecal properties, but the relationship between fecal microbiota and fecal morphologica
Publikováno v:
Scientific Reports
The role of weak acids with pH values in the range of 4–7 has been implicated in the symptoms of gastroesophageal reflux disease (GERD). Prostaglandin E2 (PGE2) is associated with heartburn symptom in GERD patients; however, the precise productive
Autor:
Itasu Ninomiya, Tomoharu Miyashita, John W. Harmon, Sachio Fushida, Keishi Nakamura, Koichi Okamoto, Ken-ichi Mukaisho, Tetsuo Ohta, Daichi Sadatomi, Shinichi Nakanuma, Katsunobu Oyama, Daisuke Matsui, Yuki Yamazaki, Hidehiro Tajima, Toru Kono, Naoki Fujitsuka, Isamu Makino, Hiroyuki Takamura, Jun Kinoshita
Publikováno v:
Surgery. 164:49-55
Background Prostaglandin E2 is one of the potential products that promotes development of tumors and also is a strong inducer of M2 phenotype macrophages, which contribute to tumor development in the immunosuppressed microenvironment. Hangeshashinto
Autor:
Daichi Sadatomi1, Kazutaka Nakashioya1, Sayaka Mamiya1, Shino Honda1, Yuka Kameyama1, Yasuo Yamamura1, Susumu Tanimura1, Kohsuke Takeda1 takeda-k@nagasaki-u.ac.jp
Publikováno v:
Journal of Biochemistry. Jun2017, Vol. 161 Issue 6, p503-512. 10p.
Autor:
Shino Honda, Daichi Sadatomi, Kohsuke Takeda, Yasuo Yamamura, Kazutaka Nakashioya, Susumu Tanimura
Publikováno v:
Cancer Science
The compound WP1066 was originally synthesized by modifying the structure of AG490, which inhibits the activation of signal transducer and activator of transcription 3 (STAT3) by directly targeting Janus kinases (JAKs). WP1066 exhibits stronger anti-
Publikováno v:
Gastroenterology. 160:S-633
Autor:
Sayaka Mamiya, Daichi Sadatomi, Tomo Yonezawa, Susumu Tanimura, Kohsuke Takeda, Mana Furuoka, Kei-ichi Ozaki
Publikováno v:
Journal of Cellular Physiology. 231:2761-2767
The intracellular cysteine protease caspase-1 is critically involved in obesity-induced inflammation in adipose tissue. A substantial body of evidence from immune cells, such as macrophages, has shown that caspase-1 activation depends largely on a pr
Autor:
Kunitsugu Kubota, Seiichi Iizuka, Yumi Harada, Hitomi Sekine, Daichi Sadatomi, Naoki Fujitsuka
Publikováno v:
Gastroenterology. 158:S-1159