Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Daichi, Nagai"'
Autor:
Daichi Nagai, Taku Shoji, Miwa Tanaka, Takanori Araki, Tetsuo Okujima, Shunji Ito, Akira Ohta, Shigeki Mori, Ryuta Sekiguchi
Publikováno v:
Chemistry - A European Journal. 23:5126-5136
Synthesis of 2-aminofuran derivatives with an azulene or N,N-dimethylanilino substituent was established by the formal [2+2] cycloaddition-retroelectrocyclization of 3-(1-azulenyl or N,N-dimethylanilino)-2-propyn-1-ols with tetracyanoethylene, follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5fea8af095bbd802a2ff66ea5febc9
https://doi.org/10.1002/chem.201700121
https://doi.org/10.1002/chem.201700121
Autor:
Takeshi Onda, Hitomi Hayashi, Hiroko Mashiba, Iwao Nakamura, Akira Masuda, Daichi Nagai, Eiji Ichimura, Hirofumi Yokoyama, Rika Goda
Publikováno v:
International Journal of Nanomedicine
Iwao Nakamura, Eiji Ichimura, Rika Goda, Hitomi Hayashi, Hiroko Mashiba, Daichi Nagai, Hirofumi Yokoyama, Takeshi Onda, Akira Masuda Nanomedicine Group, Pharmaceutical Research Laboratories, Nippon Kayaku Co., Ltd., Tokyo, Japan Abstract: In our prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58635e692dc4ed29ea396d12a62685c
https://doi.org/10.2147/ijn.s114356
https://doi.org/10.2147/ijn.s114356
Autor:
Miwa Tanaka, Ryuta Sekiguchi, Akifumi Maruyama, Taku Shoji, Daichi Nagai, Tetsuo Okujima, Shunji Ito, Mitsuhisa Maruyama
Publikováno v:
HETEROCYCLES. 95(1):353-369
Azulene-substituted tetracyanobutadienes (AzTCBDs) and dicyanoquinodimethanes (AzDCNQs) connected with naphthalene cores were prepared by the reaction of 1-azulenylalkynes with tetracyanoethylene (TCNE) and 7,7,8,8-tetracyanoquinodimethane (TCNQ) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8a9fe2286b116688951ee59ba0f2ea
https://soar-ir.repo.nii.ac.jp/records/19897
https://soar-ir.repo.nii.ac.jp/records/19897
Autor:
Taku Shoji, Masafumi Yasunami, Daichi Nagai, Kunihide Fujimori, Tetsuo Okujima, Miwa Tanaka, Shunji Ito, Kozo Toyota, Erika Shimomura, Akifumi Maruyama
Publikováno v:
ChemistrySelect. 1:49-57
Tris[(3-phenyl-1-azulenyl)tetracyanobutadiene]s and tris(aryltetracyanobutadiene)s connected to a 1,3,5-tri(1-azulenyl)benzene core (tris-AzTCBDs) have been prepared by the Pd-catalyzed alkynylation of tris(3-iodo-1-azulenyl)benzene derivative with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13c1cd2ffc9315c2a9e365583b1e20d
https://doi.org/10.1002/slct.201500036
https://doi.org/10.1002/slct.201500036
Autor:
Makiko Motoi-Ohtsuji, Hisakazu Iwai, Kunihiro Ohta, Jun Katagi, Tadayoshi Ueda, Motoharu Kakiki, Takuo Ogihara, Takuya Nagao, Sho Tanaka, Kumiko Kusumoto, Norihito Matsumoto, Daichi Nagai, Hiroshi Arakawa, Takako Ohkura, Shinya Kaneda, Emiko Ozeki, Tomoko Jomura, Yukiko Inoue
Publikováno v:
Fundamental Toxicological Sciences. 2:41-48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0df2b9662009558989cfac5b75c0e45
https://doi.org/10.2131/fts.2.41
https://doi.org/10.2131/fts.2.41
Autor:
Daichi Nagai, Osamu Miyazaki, Kazuya Okamoto, Eiji Ichimura, Yoshitaka Miyakawa, Tomio Morino, Keiko Ebara, Takeshi Onda, Keiko Sekine, Naoko Nakajima
Publikováno v:
International Journal of Cancer. 134:218-223
NK012 is a micelle-forming macromolecular prodrug of 7-ethyl-10-hydroxy camptothecin (SN-38), an active metabolite of irinotecan. It is accumulated and retained in tumor tissues and gradually releases SN-38 in an enzyme-independent manner. NK012 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::960c4d238a6c9a93120d26a162743376
https://doi.org/10.1002/ijc.28333
https://doi.org/10.1002/ijc.28333
Autor:
Yasushi Matsuzaki, Mikio Doi, Eiji Ichimura, Kiyohiro Nishikawa, Arihiro Tomura, Daichi Nagai, Rika Goda
Publikováno v:
Journal of Gastroenterology. 41:231-239
Flutamide, a nonsteroidal antiandrogen used for treatment of prostate cancer, causes a temporary increase in transaminase and in some cases severe liver dysfunction. It is dominantly metabolized by cytochrome P450 (CYP) 1A2 into 2-hydroxyflutamide (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e66bef58b7cb37e45b56ba75e9bf9ee
https://doi.org/10.1007/s00535-005-1749-y
https://doi.org/10.1007/s00535-005-1749-y
Autor:
Osamu, Miyazaki, Keiko, Sekine, Naoko, Nakajima, Eiji, Ichimura, Keiko, Ebara, Daichi, Nagai, Takeshi, Onda, Yoshitaka, Miyakawa, Kazuya, Okamoto, Tomio, Morino
Publikováno v:
International journal of cancer. 134(1)
NK012 is a micelle-forming macromolecular prodrug of 7-ethyl-10-hydroxy camptothecin (SN-38), an active metabolite of irinotecan. It is accumulated and retained in tumor tissues and gradually releases SN-38 in an enzyme-independent manner. NK012 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a166c5dbe4373c49fe0cee7da092e241
https://pubmed.ncbi.nlm.nih.gov/23775066
https://pubmed.ncbi.nlm.nih.gov/23775066
Autor:
Hiroko Mashiba, Hitomi Hayashi, Daichi Nagai, Norio Wake, Hiroaki Kobayashi, Eiji Ichimura, Kiyohiro Nishikawa, Iwao Nakamura, Kazuya Okamoto, Keiko Ebara
Publikováno v:
Arzneimittel-Forschung. 60(4)
Paclitaxel Inj. [NK] (test; paclitaxel, CAS 33069-62-4) is a generic version of the drug from the originator (reference). Both drugs contain the same active ingredient and showed identical pharmacokinetics in patients in the previous study; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7adb2253616a6f985b4263fc5c3592
https://pubmed.ncbi.nlm.nih.gov/20486471
https://pubmed.ncbi.nlm.nih.gov/20486471
Autor:
Yasushi Yamazoe, Daichi Nagai, Kouichi Yoshinari, Miki Shimada, Masato Ohbuchi, Masaaki Miyata
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 37(1)
Flutamide is used for prostate cancer therapy but occasionally induces severe liver injury. Flutamide is hydrolyzed in the body into 5-amino-2-nitrobenzotrifluoride (FLU-1) and then further oxidized. In our previous study, N-hydroxy FLU-1 (FLU-1 N-OH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2b9d8f629a7d71ffbbdf7743e7aea6
https://pubmed.ncbi.nlm.nih.gov/18832480
https://pubmed.ncbi.nlm.nih.gov/18832480