Výsledky vyhledávání - "Daiane da Rocha Janner"

Dehydroepiandrosterone improves hepatic antioxidant reserve and stimulates Akt signaling in young and old rats

Autor: Adriane Belló-Klein, Tarsila Barros Moraes, Carlos Severo Dutra Filho, Matheus Parmegiani Jahn, Maria Helena Vianna Metello Jacob, Alex Sander da Rosa Araujo, Luiz Carlos Rios Kucharski, Maria Flavia Marques Ribeiro, Daiane da Rocha Janner

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 127:331-336

This study examined, in the liver of young and old (3- and 24-month-old, respectively) healthy Wistar rats, the in vivo effect of dehydroepiandrosterone (DHEA) (10mg/kg body weight) administered subcutaneously for 5 weeks. Reduced (GSH) and oxidized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fe4b7a2c677d3e45386c0de9f25ae4
https://doi.org/10.1016/j.jsbmb.2011.07.007

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The effect of dehydroepiandrosterone (DHEA) on renal function and metabolism in diabetic rats

Autor: Luana Ferreira Gomes, Luiz Carlos Rios Kucharski, Alex Sander da Rosa Araujo, Maria Helena Vianna Metello Jacob, Maria Flavia Marques Ribeiro, Daiane da Rocha Janner, Matheus Parmegiani Jahn, Adriane Belló-Klein

Publikováno v: Steroids. 76:564-570

Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone involved in a number of biological actions in humans and rodents, but its effects on renal tissue have not yet been fully understood. The aim of this study is to assess the effect of DHEA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0012040cfc43cd16426bc3a50d5e0753
https://doi.org/10.1016/j.steroids.2011.02.006

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Autor: Daiane da Rocha Janner, Luiz Carlos Rios Kucharski, Maria Flavia Marques Ribeiro, Maria Helena Vianna Metello Jacob, Matheus Parmegiani Jahn, Adriane Belló-Klein

Publikováno v: Cell Biochemistry and Function. 28:52-57

Ageing is an inevitable biological process characterized by a general decline in various physiological functions. DHEA and DHEAS levels are maximal between the second and third life decades, then start to decline 2% per year, leaving a residual of 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97afc6468d1d8d3706d9088ce3f4b99d
https://doi.org/10.1002/cbf.1619

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Dehydroepiandrosterone modulates antioxidant enzymes and Akt signaling in healthy Wistar rat hearts

Autor: Daiane da Rocha Janner, Maria Helena Vianna Metello Jacob, Susana Llesuy, Maria Flavia Marques Ribeiro, Adriane Belló-Klein

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 112:138-144

Dehydroepiandrosterone (DHEA) is an endogenous steroid synthesized mainly in the adrenal cortex. It is known that DHEA is a precursor of sex steroids and that part of its effects depends on its conversion to estrogens and androgens. Sex steroids exer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dce8c764a384e57f4c8cbde2659f188
https://doi.org/10.1016/j.jsbmb.2008.09.008

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Redox imbalance influence in the myocardial Akt activation in aged rats treated with DHEA

Autor: Maria Flavia Marques Ribeiro, Carlos Severo Dutra Filho, Daiane da Rocha Janner, Luiz Carlos Rios Kucharski, Tarsila Barros Moraes, Adriane Belló-Klein, Alex Sander da Rosa Araujo, Matheus Parmegiani Jahn, Maria Helena Vianna Metello Jacob

Publikováno v: Experimental gerontology. 45(12)

This study examined, in young and old (3 and 24 month-old, respectively) healthy Wistar rats, the in vivo effect of DHEA (10 mg/kg body weight) administered subcutaneously for 5 weeks. Reduced (GSH) and oxidized (GSSG) glutathione levels, glucose-6-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708bd8e005fed8d5b72e89d0cd615d5a
https://pubmed.ncbi.nlm.nih.gov/20832465

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Dehydroepiandrosterone effects on Akt signaling modulation in central nervous system of young and aged healthy rats

Autor: Daiane da Rocha Janner, Maria Flavia Marques Ribeiro, Maria Helena Vianna Metello Jacob, Luiz Carlos Rios Kucharski, Matheus Parmegiani Jahn

Publikováno v: The Journal of steroid biochemistry and molecular biology. 122(4)

Dehydroepiandrosterone (DHEA) is a steroid synthesized in adrenal cortex as well as in the nervous system. DHEA effects on central nervous system (CNS) have been associated with several brain functions such as marked neurotrophic and neuroprotective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d746d5e246f509e0b8307c7d2d29f4c
https://pubmed.ncbi.nlm.nih.gov/20691781

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DHEA effects on myocardial Akt signaling modulation and oxidative stress changes in aged rats

Autor: Adriane Belló-Klein, Maria Flavia Marques Ribeiro, Maria Helena Vianna Metello Jacob, Daiane da Rocha Janner, Matheus Parmegiani Jahn, Luiz Carlos Rios Kucharski

Publikováno v: Steroids. 74(13-14)

The secretion of DHEA-synthesized mainly in the adrenal cortex-increases in the postnatal aging, peaks in the twenties and decreases with age afterwards. Exogenous DHEA can exert a dual effect depending on dose and on tissue. Akt is a serine/threonin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791d66365cce3d0d5616006efc1a6dc6
https://pubmed.ncbi.nlm.nih.gov/19699218

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