Výsledky vyhledávání - "Daiane D. Ferreira"

Acetylenic fatty acids from Porcelia macrocarpa (Annonaceae) against trypomastigotes of Trypanosoma cruzi: Effect of octadec-9-ynoic acid in plasma membrane electric potential

Autor: Juliana T. Mesquita, Andre G. Tempone, Kaio S. Gomes, João Henrique G. Lago, Gerold Jerz, Thais A. Costa-Silva, Maria Claudia Marx Young, Daiane D. Ferreira, Vinicius S. Londero

Publikováno v: Bioorganic Chemistry. 78:307-311

Porcelia macrocarpa (Warm.) R. E. Fries (Annonaceae) is an endemic plant in Brazil where its tasty pulp has been eaten fresh. The hexane extract from its flowers was subjected to chromatographic procedures to afford four acetylene derivatives identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9673ca22d5a1f8d74f3a830603ef1c
https://doi.org/10.1016/j.bioorg.2018.03.025

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Rearranged Terpenoids from the Marine Sponge Darwinella cf. oxeata and Its Predator, the Nudibranch Felimida grahami

Autor: Mario F. C. Santos, David E. Williams, Juliana R. Gubiani, Lizbeth Lorena López Parra, Daiane D. Ferreira, Vinicius Padula, Juliana T. Mesquita, Roberto G. S. Berlinck, Andre G. Tempone, Antonio G. Ferreira, Raymond J. Andersen, Eduardo Hajdu, Maria Camila A. Ramirez

Publikováno v: Journal of Natural Products. 80:720-725

Marine sponges are a rich source of terpenoids with rearranged spongian carbon skeletons. Investigation of extracts from the sponge Darwinella cf. oxeata yielded four new rearranged diterpenoids, oxeatine (2) and oxeatamides H-J (3-5), as well as the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4b14c8817599cac146297c9792368b
https://doi.org/10.1021/acs.jnatprod.6b01160

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Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis

Autor: Maiara M. Romanelli, Eduardo Caio Torres-Santos, Andrés Jimenez Galisteo, Juliana Mariotti Guerra, Thais A. Costa-Silva, Erika G. Pinto, Daiane D. Ferreira, Leandro R.S. Barbosa, Edézio Ferreira Cunha-Júnior, Andre G. Tempone

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Frontiers in Cellular and Infection Microbiology

Liposomes containing phosphatidylserine (PS) has been used for the delivery of drugs into the intramacrophage milieu. Leishmania (L.) infantum parasites live inside macrophages and cause a fatal and neglected viscerotropic disease, with a toxic treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e672e1982efac482bf1f80a9db4d125
https://www.frontiersin.org/article/10.3389/fcimb.2019.00353/full

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Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism ofLeishmania (L.) infantum

Autor: Andre G. Tempone, Juliana Quero Reimão, Daiane D. Ferreira, Juliana T. Mesquita

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016)
Evidence-based Complementary and Alternative Medicine : eCAM

Leishmaniasis and Chagas disease are neglected parasitic diseases endemic in developing countries; efforts to find new therapies remain a priority. Calcium channel blockers (CCBs) are drugs in clinical use for hypertension and other heart pathologies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab6c6cbb5ba7e56eacb1b8eb95827b9
https://doi.org/10.1155/2016/1523691

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Antitrypanosomal activity and effect in plasma membrane permeability of (-)-bornyl p-coumarate isolated from Piper cernuum (Piperaceae)

Autor: Andre G. Tempone, Ana Claudia Torrecilhas, Daiane D. Ferreira, João Henrique G. Lago, Bianca J. Novais, Thiago R. Morais, Thais A. Costa-Silva

Publikováno v: Bioorganic chemistry. 89

This work describes the isolation of six metabolites from leaves and branches of Piper cernuum (Piperaceae): (−)-cubebin (1), (−)-hinokinin (2), (−)-kusunokinin (3), trans-dehydroagarofuran (4), 11-hydroxi-4,5-secoeudesmane-4,5-dione (5), and (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab1aeea21dcf227db5a1b6c862c8d8c
https://pubmed.ncbi.nlm.nih.gov/31129501

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Efficacy of sertraline against

Autor: Cleber C. Melo-Filho, Carolina Horta Andrade, Maria de Nazaré Correia Soeiro, Bruno J. Neves, Denise da Gama Jaen Batista, Maiara M. Romanelli, Aline Nefertiti Silva da Gama, Andre G. Tempone, Cristiane França da Silva, Daiane D. Ferreira, Thaís Alves da Costa Silva, Juliana T. Mesquita

Publikováno v: The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases v.24 2018
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-12 (2018)

Background Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. Methods In this work, we studied the activity of the antidepressant drug sertraline against Trypanosoma cruzi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d6046c700b90b129626dbe154f063a
https://pubmed.ncbi.nlm.nih.gov/30450114

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Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae)

Autor: Guilherme Medeiros Antar, Aline F. Barcellos, Paulete Romoff, Thais A. Costa-Silva, João Henrique G. Lago, Daiane D. Ferreira, Juliana T. Mesquita, Andre G. Tempone, Anderson K. Ueno

Publikováno v: Fitoterapia. 125

Baccharis retusa, a medicinal Brazilian plant from Asteraceae, has been used in Brazilian folk medicine to treatment of several illnesses, including parasitic diseases. Bioactivity-guided fractionation of the n-hexane extract from the aerial parts of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec07063f5e09a465f3a92cc71a572b0e
https://pubmed.ncbi.nlm.nih.gov/29269235

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Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi

Autor: Brent R. Copp, Thaís Alves da Costa Silva, Melissa M. Cadelis, Roy Y.L. Lai, Samanta Etel Treiger Borborema, Andre G. Tempone, Angelie J. Russell, Juliana Quero Reimão, Marta L. Lima, Daiane D. Ferreira, Mariana K. Galuppo, Graham Michael Wynne, Juliana Mariotti Guerra

Publikováno v: European journal of medicinal chemistry. 139

The neglected tropical diseases Chagas disease and leishmaniasis affect together more than 20 million people living mainly in developing countries. The mainstay of treatment is chemotherapy, however the drugs of choice, which include benznidazole and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7996d0c0dd4680638e14bf15f7b1be10
https://pubmed.ncbi.nlm.nih.gov/28881289

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Gibbilimbol analogues as antiparasitic agents--Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum

Autor: Andre G. Tempone, João Henrique G. Lago, Anderson K. Ueno, Roberto Z. Dias, Ligia F. Martins, Marina T. Varela, Daiane D. Ferreira, João Paulo S. Fernandes

Publikováno v: Bioorganicmedicinal chemistry letters. 26(4)

The essential oils from leaves of Piper malacophyllum (Piperaceae) showed to be mainly composed by two alkenylphenol derivatives: gibbilimbols A and B. After isolation and structural characterization by NMR and MS data analysis, both compounds were e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fb587e291e0939f1b0229df0972d86
https://pubmed.ncbi.nlm.nih.gov/26821820

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