Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Dai-Shi Tian"'
Autor:
Yue Tang, Ming-Hao Dong, Xiao-Wei Pang, Hang Zhang, Yun-Hui Chu, Luo-Qi Zhou, Sheng Yang, Lu-Yang Zhang, Yun-Fan You, Li-Fang Zhu, Wei Wang, Chuan Qin, Dai-Shi Tian
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Circulating miR-30c-2-3p has been closely related to vascular diseases, however, its role and underlying mechanisms in ischemic stroke remained unclear. Our study addressed this gap by observing elevated levels of exosomal miR-30c-2-3p in pa
Externí odkaz:
https://doaj.org/article/1ef79620e5954a4292516fb148491c7b
Autor:
Lu-Lu Xu, Sheng Yang, Luo-Qi Zhou, Yun-Hui Chu, Xiao-Wei Pang, Yun-Fan You, Hang Zhang, Lu-Yang Zhang, Li-Fang Zhu, Lian Chen, Ke Shang, Jun Xiao, Wei Wang, Dai-Shi Tian, Chuan Qin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Chronic cerebral hypoperfusion (CCH), a disease afflicting numerous individuals worldwide, is a primary cause of cognitive deficits, the pathogenesis of which remains poorly understood. Bruton’s tyrosine kinase inhibition (BTKi) is conside
Externí odkaz:
https://doaj.org/article/116ae8d96fbb4adba3e3cbc90badd584
Autor:
Lu‐Yang Zhang, Yun‐Hui Chu, Yun‐Fan You, Ming‐Hao Dong, Xiao‐Wei Pang, Lian Chen, Li‐Fang Zhu, Sheng Yang, Luo‐Qi Zhou, Ke Shang, Gang Deng, Jun Xiao, Wei Wang, Chuan Qin, Dai‐Shi Tian
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Background Stroke is a leading cause of death worldwide, with a lack of effective treatments for improving the prognosis. The aim of the present study was to identify novel therapeutic targets for functional outcome after ischemic stroke . Methods an
Externí odkaz:
https://doaj.org/article/e483fbd106114773a1a7c85bb90ee18b
Autor:
Dai-Shi Tian, Chuan Qin, Ming-Hao Dong, Michael Heming, Luo-Qi Zhou, Wen Wang, Song-Bai Cai, Yun-Fan You, Ke Shang, Jun Xiao, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Gerd Meyer zu Hörste, Wei Wang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 966-987 (2024)
Abstract B-cell maturation antigen (BCMA), expressed in plasmablasts and plasma cells, could serve as a promising therapeutic target for autoimmune diseases. We reported here chimeric antigen receptor (CAR) T cells targeting BCMA in two patients with
Externí odkaz:
https://doaj.org/article/bbc6bbd3f3864e94abcc50e72aa7cf93
Autor:
Sheng Yang, Chuan Qin, Man Chen, Yun‐Hui Chu, Yue Tang, Luo‐Qi Zhou, Hang Zhang, Ming‐Hao Dong, Xiao‐Wei Pang, Lian Chen, Long‐Jun Wu, Dai‐Shi Tian, Wei Wang
Publikováno v:
Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract Microglia, the major resident immune cells in the central nervous system, serve as the frontline soldiers against cerebral ischemic injuries, possibly along with metabolic alterations. However, signaling pathways involved in the regulation o
Externí odkaz:
https://doaj.org/article/f6b9009f4a954c11b65cd093810c441d
Autor:
Lian Chen, Li-Fang Zhu, Lu-Yang Zhang, Yun-Hui Chu, Ming-Hao Dong, Xiao-Wei Pang, Sheng Yang, Luo-Qi Zhou, Ke Shang, Jun Xiao, Wei Wang, Chuan Qin, Dai-Shi Tian
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundGrowing evidence links immunological responses to Multiple sclerosis (MS), but specific immune factors are still unclear.MethodsMendelian randomization (MR) was performed to investigate the association between peripheral hematological trait
Externí odkaz:
https://doaj.org/article/89127e06f18348a79ec470760056cb25
Autor:
Yun-Fan You, Man Chen, Yue Tang, Wen-Xiang Yu, Xiao-Wei Pang, Yun-Hui Chu, Hang Zhang, Ke Shang, Gang Deng, Luo-Qi Zhou, Sheng Yang, Wei Wang, Jun Xiao, Dai-Shi Tian, Chuan Qin
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are activated and play a pivotal role in response to tissue injury. Tr
Externí odkaz:
https://doaj.org/article/640bed233aa54a44b7d224c0af3bb0b4
Autor:
Chuan Qin, Dai-Shi Tian, Luo-Qi Zhou, Ke Shang, Liang Huang, Ming-Hao Dong, Yun-Fan You, Jun Xiao, Ying Xiong, Wen Wang, Hao Pang, Jing-Jing Guo, Song-Bai Cai, Di Wang, Chun-Rui Li, Min Zhang, Bi-Tao Bu, Wei Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA) have great potentials in autoimmune diseases and could be novel therapeutics for relapsed/refractory neuromyelitis optica spectrum disorder (NMOSD).
Externí odkaz:
https://doaj.org/article/1eb0bdae0281405d8d2cb3547cd24f23
Autor:
Xin Chen, Jun Xiao, Luo-Qi Zhou, Wen-Xiang Yu, Man Chen, Yun-Hui Chu, Ke Shang, Gang Deng, Wen-Hui Song, Chuan Qin, Deng-Ji Pan, Dai-Shi Tian
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating diseases of the central nervous system, have drawn the attention of many researchers due to the relapsing courses and cumulative disability. A first bibliometric analysis of NMOSD was
Externí odkaz:
https://doaj.org/article/80c8f03c939b4a40bad7b049b48a1d37
Autor:
Chuan Qin, Sheng Yang, Yun-Hui Chu, Hang Zhang, Xiao-Wei Pang, Lian Chen, Luo-Qi Zhou, Man Chen, Dai-Shi Tian, Wei Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-29 (2022)
Abstract Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces severe neural injuries, and is one of the leading causes of death and disability worldwide. Thus, it is of great necessity to further detailly eluci
Externí odkaz:
https://doaj.org/article/e6255712a6c74304a8ce785719fbc11d